Future perspectives in melanoma research. Meeting report from the " Melanoma Bridge. Napoli, December 2nd-4th 2012"

Paolo A. Ascierto, Antonio M. Grimaldi, Nicolas Acquavella, Lorenzo Borgognoni, Luana Calabrò, Natale Cascinelli, Alessandra Cesano, Michele Del Vecchio, Alexander M. Eggermont, Mark Faries, Soldano Ferrone, Bernard A. Fox, Thomas F. Gajewski, Jérôme Galon, Sacha Gnjatic, Helen Gogas, Mohammed Kashani-Sabet, Howard L. Kaufman, James Larkin, Roger S. LoAlberto Mantovani, Kim Margolin, Cornelis Melief, Grant McArthur, Giuseppe Palmieri, Igor Puzanov, Antoni Ribas, Barbara Seliger, Jeff Sosman, Peter Suenaert, Ahmad A. Tarhini, Giorgio Trinchieri, Fernando Vidal-Vanaclocha, Ena Wang, Gennaro Ciliberto, Nicola Mozzillo, Francesco M. Marincola, Magdalena Thurin

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Abstract

Recent insights into the genetic and somatic aberrations have initiated a new era of rapidly evolving targeted and immune-based treatments for melanoma. After decades of unsuccessful attempts to finding a more effective cure in the treatment of melanoma now we have several drugs active in melanoma. The possibility to use these drugs in combination to improve responses to overcome the resistance, to potentiate the action of immune system with the new immunomodulating antibodies, and identification of biomarkers that can predict the response to a particular therapy represent new concepts and approaches in the clinical management of melanoma. The third " Melanoma Research: " A bridge from Naples to the World" meeting, shortened as " Bridge Melanoma Meeting" took place in Naples, December 2 to 4th, 2012. The four topics of discussion at this meeting were: advances in molecular profiling and novel biomarkers, combination therapies, novel concepts toward integrating biomarkers and therapies into contemporary clinical management of patients with melanoma across the entire spectrum of disease stage, and the knowledge gained from the biology of tumor microenvironment across different tumors as a bridge to impact on prognosis and response to therapy in melanoma. This international congress gathered more than 30 international faculty members who in an interactive atmosphere which stimulated discussion and exchange of their experience regarding the most recent advances in research and clinical management of melanoma patients.

Original languageEnglish
Article number137
JournalJournal of translational medicine
Volume11
Issue number1
DOIs
Publication statusPublished - 3 Jun 2013

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Ascierto, P. A., Grimaldi, A. M., Acquavella, N., Borgognoni, L., Calabrò, L., Cascinelli, N., Cesano, A., Del Vecchio, M., Eggermont, A. M., Faries, M., Ferrone, S., Fox, B. A., Gajewski, T. F., Galon, J., Gnjatic, S., Gogas, H., Kashani-Sabet, M., Kaufman, H. L., Larkin, J., ... Thurin, M. (2013). Future perspectives in melanoma research. Meeting report from the " Melanoma Bridge. Napoli, December 2nd-4th 2012". Journal of translational medicine, 11(1), [137]. https://doi.org/10.1186/1479-5876-11-137