Failure to define the pathogenesis and treatment of human diabetic neuropathy

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2 Citations (Scopus)


The clinical manifestations, underlying pathology and aetiology of human diabetic neuropathy are varied and complex. Much data has been generated from preclinical models to provide a conceptual framework for the cause and treatment of human diabetic neuropathy. Despite this there remains much debate and controversy on the pathophysiology of the condition. Furthermore, many of the interventions reaching phase III clinical trials have failed to prove effective. To date we have no evidence-based and effective treatment(s) for human diabetic neuropathy.

Original languageEnglish
Pages (from-to)107-111
Number of pages5
JournalBritish Journal of Diabetes and Vascular Disease
Issue number2
Publication statusPublished - 1 Jan 2003



  • Clinical trials
  • Diabetes
  • Metabolic
  • Neuropathy
  • Vascular

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine

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