Excess weight and sleep-disordered breathing

Terry Young, Paul E. Peppard, Shahrad Taheri

Research output: Contribution to journalReview article

466 Citations (Scopus)

Abstract

Excess weight is a well-established predictor of sleep-disordered breathing (SDB). Clinical observations and population studies throughout the United States, Europe, Asia, and Australia have consistently shown a graded increase in the prevalence of SDB as body mass index, neck girth, or other measures of body habitus increases. Clinical studies of weight loss and longitudinal population studies provide strong support for a causal association. The role of excess body weight, a modifiable risk factor, with SDB raises many questions relevant to clinical practice and public health. The topic takes on added importance with the alarming rate of weight gain in children as well as adults in industrialized nations. Among adults ages 30-69 yr, averaging over the estimated United States 2003 age, sex, and BMI distributions, we estimate that ∼17% of adults have mild or worse SDB (apnea-hypopnea index ≥ 5) and that 41% of those adults have SDB " attributable" to having a body mass index of ≥25 kg/m2. Similarly, we estimate that -5.7% of adults have moderate or worse SDB (apnea-hypopnea index ≥ 15) and that 58% of those adults have SDB attributable to excess weight. Clearly, if the expanding epidemic of obesity seen in the United States continues, the prevalence of, SDB will almost certainly increase, along with the proportion of SDB attributable to obesity.

Original languageEnglish
Pages (from-to)1592-1599
Number of pages8
JournalJournal of Applied Physiology
Volume99
Issue number4
DOIs
Publication statusPublished - 1 Oct 2005

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Keywords

  • Apnea-hypopnea index
  • Body mass index

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

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