Evidence of curcumin and curcumin analogue effects in skin diseases: A narrative review

Yunes Panahi, Omid Fazlolahzadeh, Stephen Atkin, Muhammed Majeed, Alexandra E. Butler, Thomas P. Johnston, Amirhossein Sahebkar

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Curcumin, a natural polyphenolic and yellow pigment obtained from the spice turmeric, has strong antioxidative, anti-inflammatory, and antibacterial properties. Due to these properties, curcumin has been used as a remedy for the prevention and treatment of skin aging and disorders such as psoriasis, infection, acne, skin inflammation, and skin cancer. Curcumin has protective effects against skin damage caused by chronic ultraviolet B radiation. One of the challenges in maximizing the therapeutic potential of curcumin is its low bioavailability, limited aqueous solubility, and chemical instability. In this regard, the present review is focused on recent studies concerning the use of curcumin for the treatment of skin diseases, as well as offering new and efficient strategies to optimize its pharmacokinetic profile and increase its bioavailability.

Original languageEnglish
JournalJournal of Cellular Physiology
DOIs
Publication statusAccepted/In press - 1 Jan 2018

    Fingerprint

Keywords

  • curcumin
  • dermatology
  • inflammation
  • skin
  • topical use

ASJC Scopus subject areas

  • Physiology
  • Clinical Biochemistry
  • Cell Biology

Cite this

Panahi, Y., Fazlolahzadeh, O., Atkin, S., Majeed, M., Butler, A. E., Johnston, T. P., & Sahebkar, A. (Accepted/In press). Evidence of curcumin and curcumin analogue effects in skin diseases: A narrative review. Journal of Cellular Physiology. https://doi.org/10.1002/jcp.27096