Evidence for lateral gene transfer between archaea and bacteria from genome sequence of Thermotoga maritima

Karen E. Nelson, Rebecca A. Clayton, Steven R. Gill, Michelle L. Gwinn, Robert J. Dodson, Daniel H. Haft, Erin K. Hickey, Jeremy D. Peterson, William C. Nelson, Karen A. Ketchum, Lisa McDonald, Teresa R. Utterback, Joel Malek, Katja D. Linher, Mina M. Garrett, Ashley M. Stewart, Matthew D. Cotton, Matthew S. Pratt, Cheryl A. Phillips, Delwood Richardson & 9 others John Heidelberg, Granger G. Sutton, Robert D. Fleischmann, Jonathan A. Eisen, Owen White, Steven L. Salzberg, Hamilton O. Smith, J. Craig Venter, Claire M. Fraser

Research output: Contribution to journalArticle

1124 Citations (Scopus)

Abstract

The 1,860,725-base-pair genome of Thermotoga maritima MSB8 contains 1,877 predicted coding regions, 1,014 (54%) of which have functional assignments and 863 (46%) of which are of unknown function. Genome analysis reveals numerous pathways Involved in degradation of sugars and plant polysaccharides, and 108 genes that have orthologues only in the genomes of other thermophilic Eubacteria and Archaea. Of the Eubacteria sequenced to date, T. maritima has the highest percentage (24%) of genes that are most similar to archaeal genes. Eighty-one archaeal-like genes are clustered in 15 regions of the T. maritima genome that range In size from 4 to 20 kilobases. Conservation of gene order between T. maritima and Archaea In many of the clustered regions suggests that lateral gene transfer may have occurred between thermophilic Eubacteria and Archaea.

Original languageEnglish
Pages (from-to)323-329
Number of pages7
JournalNature
Volume399
Issue number6734
DOIs
Publication statusPublished - 27 May 1999
Externally publishedYes

Fingerprint

Thermotoga maritima
Horizontal Gene Transfer
Archaea
Archaeal Genes
Genome
Bacteria
Gene Order
Base Pairing
Genes
Polysaccharides

ASJC Scopus subject areas

  • General

Cite this

Nelson, K. E., Clayton, R. A., Gill, S. R., Gwinn, M. L., Dodson, R. J., Haft, D. H., ... Fraser, C. M. (1999). Evidence for lateral gene transfer between archaea and bacteria from genome sequence of Thermotoga maritima. Nature, 399(6734), 323-329. https://doi.org/10.1038/20601

Evidence for lateral gene transfer between archaea and bacteria from genome sequence of Thermotoga maritima. / Nelson, Karen E.; Clayton, Rebecca A.; Gill, Steven R.; Gwinn, Michelle L.; Dodson, Robert J.; Haft, Daniel H.; Hickey, Erin K.; Peterson, Jeremy D.; Nelson, William C.; Ketchum, Karen A.; McDonald, Lisa; Utterback, Teresa R.; Malek, Joel; Linher, Katja D.; Garrett, Mina M.; Stewart, Ashley M.; Cotton, Matthew D.; Pratt, Matthew S.; Phillips, Cheryl A.; Richardson, Delwood; Heidelberg, John; Sutton, Granger G.; Fleischmann, Robert D.; Eisen, Jonathan A.; White, Owen; Salzberg, Steven L.; Smith, Hamilton O.; Venter, J. Craig; Fraser, Claire M.

In: Nature, Vol. 399, No. 6734, 27.05.1999, p. 323-329.

Research output: Contribution to journalArticle

Nelson, KE, Clayton, RA, Gill, SR, Gwinn, ML, Dodson, RJ, Haft, DH, Hickey, EK, Peterson, JD, Nelson, WC, Ketchum, KA, McDonald, L, Utterback, TR, Malek, J, Linher, KD, Garrett, MM, Stewart, AM, Cotton, MD, Pratt, MS, Phillips, CA, Richardson, D, Heidelberg, J, Sutton, GG, Fleischmann, RD, Eisen, JA, White, O, Salzberg, SL, Smith, HO, Venter, JC & Fraser, CM 1999, 'Evidence for lateral gene transfer between archaea and bacteria from genome sequence of Thermotoga maritima', Nature, vol. 399, no. 6734, pp. 323-329. https://doi.org/10.1038/20601
Nelson KE, Clayton RA, Gill SR, Gwinn ML, Dodson RJ, Haft DH et al. Evidence for lateral gene transfer between archaea and bacteria from genome sequence of Thermotoga maritima. Nature. 1999 May 27;399(6734):323-329. https://doi.org/10.1038/20601
Nelson, Karen E. ; Clayton, Rebecca A. ; Gill, Steven R. ; Gwinn, Michelle L. ; Dodson, Robert J. ; Haft, Daniel H. ; Hickey, Erin K. ; Peterson, Jeremy D. ; Nelson, William C. ; Ketchum, Karen A. ; McDonald, Lisa ; Utterback, Teresa R. ; Malek, Joel ; Linher, Katja D. ; Garrett, Mina M. ; Stewart, Ashley M. ; Cotton, Matthew D. ; Pratt, Matthew S. ; Phillips, Cheryl A. ; Richardson, Delwood ; Heidelberg, John ; Sutton, Granger G. ; Fleischmann, Robert D. ; Eisen, Jonathan A. ; White, Owen ; Salzberg, Steven L. ; Smith, Hamilton O. ; Venter, J. Craig ; Fraser, Claire M. / Evidence for lateral gene transfer between archaea and bacteria from genome sequence of Thermotoga maritima. In: Nature. 1999 ; Vol. 399, No. 6734. pp. 323-329.
@article{fb6c13617fca40148966759ace99b943,
title = "Evidence for lateral gene transfer between archaea and bacteria from genome sequence of Thermotoga maritima",
abstract = "The 1,860,725-base-pair genome of Thermotoga maritima MSB8 contains 1,877 predicted coding regions, 1,014 (54{\%}) of which have functional assignments and 863 (46{\%}) of which are of unknown function. Genome analysis reveals numerous pathways Involved in degradation of sugars and plant polysaccharides, and 108 genes that have orthologues only in the genomes of other thermophilic Eubacteria and Archaea. Of the Eubacteria sequenced to date, T. maritima has the highest percentage (24{\%}) of genes that are most similar to archaeal genes. Eighty-one archaeal-like genes are clustered in 15 regions of the T. maritima genome that range In size from 4 to 20 kilobases. Conservation of gene order between T. maritima and Archaea In many of the clustered regions suggests that lateral gene transfer may have occurred between thermophilic Eubacteria and Archaea.",
author = "Nelson, {Karen E.} and Clayton, {Rebecca A.} and Gill, {Steven R.} and Gwinn, {Michelle L.} and Dodson, {Robert J.} and Haft, {Daniel H.} and Hickey, {Erin K.} and Peterson, {Jeremy D.} and Nelson, {William C.} and Ketchum, {Karen A.} and Lisa McDonald and Utterback, {Teresa R.} and Joel Malek and Linher, {Katja D.} and Garrett, {Mina M.} and Stewart, {Ashley M.} and Cotton, {Matthew D.} and Pratt, {Matthew S.} and Phillips, {Cheryl A.} and Delwood Richardson and John Heidelberg and Sutton, {Granger G.} and Fleischmann, {Robert D.} and Eisen, {Jonathan A.} and Owen White and Salzberg, {Steven L.} and Smith, {Hamilton O.} and Venter, {J. Craig} and Fraser, {Claire M.}",
year = "1999",
month = "5",
day = "27",
doi = "10.1038/20601",
language = "English",
volume = "399",
pages = "323--329",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "6734",

}

TY - JOUR

T1 - Evidence for lateral gene transfer between archaea and bacteria from genome sequence of Thermotoga maritima

AU - Nelson, Karen E.

AU - Clayton, Rebecca A.

AU - Gill, Steven R.

AU - Gwinn, Michelle L.

AU - Dodson, Robert J.

AU - Haft, Daniel H.

AU - Hickey, Erin K.

AU - Peterson, Jeremy D.

AU - Nelson, William C.

AU - Ketchum, Karen A.

AU - McDonald, Lisa

AU - Utterback, Teresa R.

AU - Malek, Joel

AU - Linher, Katja D.

AU - Garrett, Mina M.

AU - Stewart, Ashley M.

AU - Cotton, Matthew D.

AU - Pratt, Matthew S.

AU - Phillips, Cheryl A.

AU - Richardson, Delwood

AU - Heidelberg, John

AU - Sutton, Granger G.

AU - Fleischmann, Robert D.

AU - Eisen, Jonathan A.

AU - White, Owen

AU - Salzberg, Steven L.

AU - Smith, Hamilton O.

AU - Venter, J. Craig

AU - Fraser, Claire M.

PY - 1999/5/27

Y1 - 1999/5/27

N2 - The 1,860,725-base-pair genome of Thermotoga maritima MSB8 contains 1,877 predicted coding regions, 1,014 (54%) of which have functional assignments and 863 (46%) of which are of unknown function. Genome analysis reveals numerous pathways Involved in degradation of sugars and plant polysaccharides, and 108 genes that have orthologues only in the genomes of other thermophilic Eubacteria and Archaea. Of the Eubacteria sequenced to date, T. maritima has the highest percentage (24%) of genes that are most similar to archaeal genes. Eighty-one archaeal-like genes are clustered in 15 regions of the T. maritima genome that range In size from 4 to 20 kilobases. Conservation of gene order between T. maritima and Archaea In many of the clustered regions suggests that lateral gene transfer may have occurred between thermophilic Eubacteria and Archaea.

AB - The 1,860,725-base-pair genome of Thermotoga maritima MSB8 contains 1,877 predicted coding regions, 1,014 (54%) of which have functional assignments and 863 (46%) of which are of unknown function. Genome analysis reveals numerous pathways Involved in degradation of sugars and plant polysaccharides, and 108 genes that have orthologues only in the genomes of other thermophilic Eubacteria and Archaea. Of the Eubacteria sequenced to date, T. maritima has the highest percentage (24%) of genes that are most similar to archaeal genes. Eighty-one archaeal-like genes are clustered in 15 regions of the T. maritima genome that range In size from 4 to 20 kilobases. Conservation of gene order between T. maritima and Archaea In many of the clustered regions suggests that lateral gene transfer may have occurred between thermophilic Eubacteria and Archaea.

UR - http://www.scopus.com/inward/record.url?scp=0033609333&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033609333&partnerID=8YFLogxK

U2 - 10.1038/20601

DO - 10.1038/20601

M3 - Article

VL - 399

SP - 323

EP - 329

JO - Nature

JF - Nature

SN - 0028-0836

IS - 6734

ER -