Evaluation of shear stress accumulation on blood components in normal and dysfunctional bileaflet mechanical heart valves using smoothed particle hydrodynamics

S. Shahriari, H. Maleki, Ibrahim Hassan, L. Kadem

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Evaluating shear induced hemodynamic complications is one of the major concerns in design of the mechanical heart valves (MHVs). The monitoring of these events relies on both numerical simulations and experimental measurements. Currently, numerical approaches are mainly based on a combined Eulerian-Lagrangian approach. A more straightforward evaluation can be based on the Lagrangian analysis of the whole blood. As a consequence, Lagrangian meshfree methods are more adapted to such evaluation. In this study, smoothed particle hydrodynamics (SPH), a fully meshfree particle method originated to simulate compressible astrophysical flows, is applied to study the flow through a normal and a dysfunctional bileaflet mechanical heart valves (BMHVs). The SPH results are compared with the reference data. The accumulation of shear stress patterns on blood components illustrates the important role played by non-physiological flow patterns and mainly vortical structures in this issue. The statistical distribution of particles with respect to shear stress loading history provides important information regarding the relative number of blood components that can be damaged. This can be used as a measure of the response of blood components to the presence of the valve implant or any implantable medical device. This work presents the first attempt to simulate pulsatile flow through BMHVs using SPH method.

Original languageEnglish
Pages (from-to)2637-2644
Number of pages8
JournalJournal of Biomechanics
Volume45
Issue number15
DOIs
Publication statusPublished - 11 Oct 2012
Externally publishedYes

Fingerprint

Heart Valves
Hydrodynamics
Shear stress
Blood
Statistical Distributions
Pulsatile Flow
Pulsatile flow
Compressible flow
Hemodynamics
Flow patterns
History
Equipment and Supplies
Monitoring
Computer simulation

Keywords

  • Bileaflet mechanical heart valve
  • Blood components damage
  • Fully Lagrangian meshfree method
  • Hemodynamics
  • Shear stress accumulation
  • Smoothed particle hydrodynamics

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Rehabilitation
  • Biophysics
  • Biomedical Engineering

Cite this

Evaluation of shear stress accumulation on blood components in normal and dysfunctional bileaflet mechanical heart valves using smoothed particle hydrodynamics. / Shahriari, S.; Maleki, H.; Hassan, Ibrahim; Kadem, L.

In: Journal of Biomechanics, Vol. 45, No. 15, 11.10.2012, p. 2637-2644.

Research output: Contribution to journalArticle

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