Environmental lung disease and the interstitium

P. B. Bitterman, S. I. Rennard, Ronald Crystal

Research output: Contribution to journalReview article

17 Citations (Scopus)


The purpose of this review is to describe the importance of the interstitium in lung disorders caused by the inhalation of foreign materials. To do so, we first describe the cellular and noncellular components of the normal interstitium. With this as a background, we then review the current concepts of those mechanisms by which inhaled agents may induce acute and chronic lung disease. Whenever possible, the data and concepts presented will be those established in humans.

Original languageEnglish
Pages (from-to)393-412
Number of pages20
JournalClinics in Chest Medicine
Issue number3
Publication statusPublished - 1 Dec 1981
Externally publishedYes


ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Bitterman, P. B., Rennard, S. I., & Crystal, R. (1981). Environmental lung disease and the interstitium. Clinics in Chest Medicine, 2(3), 393-412.