Endoplasmic reticulum in the heart, a forgotten organelle?

Nasrin Mesaeli, K. Nakamura, M. Opas, M. Michalak

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Our hypothesis is that sarcoplasmic and endoplasmic reticulum Ca 2+ stores may be functionally distinct compartments in cardiomyocytes. Sarcoplasmic reticulum Ca 2+ store is responsible for control of excitation-contraction coupling whereas endoplasmic reticulum compartment may provide Ca 2+ for housekeeping and transcriptional functions.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalMolecular and Cellular Biochemistry
Volume225
Issue number1-2
DOIs
Publication statusPublished - 2001
Externally publishedYes

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Keywords

  • Calreticulin
  • Cardiac development
  • Endoplasmic reticulum
  • Sarcoplasmic reticulum

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

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