Electroencephalographic and cranial ultrasound studies in neonates treated with extracorporeal membrane oxygenation

L. J. Graziani, Leopold Streletz, M. S. Kornhauser, D. G. Mitchell, P. J. Wolfson, D. A. Merton, H. J. Desai, S. A. Desai, J. Cullen, A. Bhat, N. B. Robinson

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Forty-six neonatal infants treated with extracorporeal membrane oxygenation (ECMO) because of respiratory failure had cranial ultrasound (US) and EEG studies during and within one week following ECMO. All had US studies and 12 had EEGs prior to ECMO therapy. An EEG was also obtained in three infants during cannulation of the right common carotid artery (RCCA). The purpose of the studies was to determine whether focal EEG and/or localized US abnormalities follow cannulation and permanent ligation of the RCCA and right internal jugular vein (RIJV). The EEGs were examined for focality and degree of abnormality. Though not statistically significant, EEG abnormalities were more often preponderant over the right than the left hemisphere, but were usually generalized. EEG abnormalities were frequently noted during and following ECMO, but also occurred in 10 of the 12 infants studied prior to ECMO. Within five days following termination of ECMO, there was a statistically significant decrease in the severity and frequency of EEG abnormalities. Cranial ultrasound abnormalities were not significantly lateralized, though abnormalities were noted in many infants before ECMO and in most during and immediately following the procedure. We conclude that there were no consistently lateralized US or EEG abnormalities related to ligation of the RCCA and RIJV during and following ECMO in the present series. The abnormal EEG and US findings, which are probably related to the pre-existing respiratory failure, require further studies to determine their pathogenesis and prognosis.

Original languageEnglish
Pages (from-to)71-75
Number of pages5
JournalPediatric Reviews and Communications
Volume4
Issue number1-2
Publication statusPublished - 1989
Externally publishedYes

Fingerprint

Extracorporeal Membrane Oxygenation
Electroencephalography
Newborn Infant
Common Carotid Artery
Jugular Veins
Catheterization
Respiratory Insufficiency
Ligation

Keywords

  • Cranial ultrasound
  • ECMO
  • Neonatal EEG
  • Neonatal respiratory failure
  • Newborn

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Graziani, L. J., Streletz, L., Kornhauser, M. S., Mitchell, D. G., Wolfson, P. J., Merton, D. A., ... Robinson, N. B. (1989). Electroencephalographic and cranial ultrasound studies in neonates treated with extracorporeal membrane oxygenation. Pediatric Reviews and Communications, 4(1-2), 71-75.

Electroencephalographic and cranial ultrasound studies in neonates treated with extracorporeal membrane oxygenation. / Graziani, L. J.; Streletz, Leopold; Kornhauser, M. S.; Mitchell, D. G.; Wolfson, P. J.; Merton, D. A.; Desai, H. J.; Desai, S. A.; Cullen, J.; Bhat, A.; Robinson, N. B.

In: Pediatric Reviews and Communications, Vol. 4, No. 1-2, 1989, p. 71-75.

Research output: Contribution to journalArticle

Graziani, LJ, Streletz, L, Kornhauser, MS, Mitchell, DG, Wolfson, PJ, Merton, DA, Desai, HJ, Desai, SA, Cullen, J, Bhat, A & Robinson, NB 1989, 'Electroencephalographic and cranial ultrasound studies in neonates treated with extracorporeal membrane oxygenation', Pediatric Reviews and Communications, vol. 4, no. 1-2, pp. 71-75.
Graziani, L. J. ; Streletz, Leopold ; Kornhauser, M. S. ; Mitchell, D. G. ; Wolfson, P. J. ; Merton, D. A. ; Desai, H. J. ; Desai, S. A. ; Cullen, J. ; Bhat, A. ; Robinson, N. B. / Electroencephalographic and cranial ultrasound studies in neonates treated with extracorporeal membrane oxygenation. In: Pediatric Reviews and Communications. 1989 ; Vol. 4, No. 1-2. pp. 71-75.
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