Efficacy of selective arterial embolisation for the treatment of life-threatening post-partum haemorrhage in a large population

Cyril Touboul, Wassim Badiou, Julien Saada, Jean Pierre Pelage, Didier Payen, Eric Vicaut, Denis Jacob, Arash Rafii Tabrizi

Research output: Contribution to journalArticle

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Abstract

Background: The objective of this study was to assess efficacy and determine the optimal indication of selective arterial embolisation (SAE) in patients with life-threatening post-partum haemorrhage (PPH). Methodology/Principal Findings:One hundred and two patients with PPH underwent SAE and were included from January 1998 to January 2002 in our university care center. Embolisation was considered effective when no other surgical procedure was required. Univariate and multivariate statistical analysis were performed. SAE was effective for 73 patients (71.5%), while 29 required surgical procedures. SAE was effective in 88.6% of women with uterine atony that was associated with positive outcome (OR 4.13, 1.35-12.60), whereas caesarean deliveries (OR 0.16, 0.04-0.5) and haemodynamic shock (OR 0.21, 0.07-0.60) were associated with high failure rates, 47.6% and 39.1%, respectively. Conclusions/Significance:Success rate for SAE observed in a large population is lower than previously reported. It is most likely to succeed for uterine atony but not recommended in case of haemodynamic shock or after caesarean section.

Original languageEnglish
Article numbere3819
JournalPLoS One
Volume3
Issue number11
DOIs
Publication statusPublished - 26 Nov 2008
Externally publishedYes

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Hemodynamics
Uterine Inertia
hemorrhage
hemodynamics
Hemorrhage
Shock
surgery
Population
Statistical methods
cesarean section
Cesarean Section
multivariate analysis
Therapeutics
Multivariate Analysis
methodology

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Efficacy of selective arterial embolisation for the treatment of life-threatening post-partum haemorrhage in a large population. / Touboul, Cyril; Badiou, Wassim; Saada, Julien; Pelage, Jean Pierre; Payen, Didier; Vicaut, Eric; Jacob, Denis; Tabrizi, Arash Rafii.

In: PLoS One, Vol. 3, No. 11, e3819, 26.11.2008.

Research output: Contribution to journalArticle

Touboul, Cyril ; Badiou, Wassim ; Saada, Julien ; Pelage, Jean Pierre ; Payen, Didier ; Vicaut, Eric ; Jacob, Denis ; Tabrizi, Arash Rafii. / Efficacy of selective arterial embolisation for the treatment of life-threatening post-partum haemorrhage in a large population. In: PLoS One. 2008 ; Vol. 3, No. 11.
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