Manufacturing high-performance cathodes requires optimization of conventional processing techniques to novel ones capable of controlling the microstructure. Spray pyrolysis is one of those promising techniques for tailoring microstructure of the electrodes for better performance of solid oxide fuel cells (SOFCs). This paper reports the effect of solvent and precursor type, deposition temperature and spray speed on morphology and compositional homogeneity of the lanthanum strontium manganite (LSM) cathode. Results show that metal-organic precursors and organic solvent create a homogeneous crack-free deposition as opposed to aqueous solution. By changing the temperature gradually from 540 to 580°C and spray speed from 0.73 to 1.58 ml/min, an appreciable trend was observed in amount of porosity in LSM cathode microstructure. It was shown that increasing the temperature and spray speed results in formation of more porous microstructure. The microstructure, morphology and the compositional homogeneity of the fabricated cathodes were characterized using SEM, EDS and XRD.