Does Equol production determine soy endocrine effects?

Dana Shor, Thozhukat Sathyapalan, Stephen Atkin, Natalie J. Thatcher

Research output: Contribution to journalReview article

35 Citations (Scopus)

Abstract

Isoflavones, a group of phytoestrogens, are selective oestrogen receptor (ER) modulators. They may positively impact endocrine-related conditions but the current evidence is sparse. Equol, a non-steroidal oestrogen, is produced by the metabolism of the isoflavone daidzein by intestinal bacteria. In Western countries, 30-50% of individuals metabolize daidzein into equol and are known as equol producers. Equol production may be the source of benefit from isoflavones in endocrine disease.

Original languageEnglish
Pages (from-to)389-398
Number of pages10
JournalEuropean Journal of Nutrition
Volume51
Issue number4
DOIs
Publication statusPublished - Jun 2012
Externally publishedYes

Fingerprint

Equol
Isoflavones
Non-Steroidal Estrogens
Endocrine System Diseases
Selective Estrogen Receptor Modulators
Phytoestrogens
Bacteria

Keywords

  • Breast cancer
  • Cardiovascular disease
  • Equol
  • Isoflavone
  • Osteoporosis
  • Phytoestrogen
  • Soy

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Does Equol production determine soy endocrine effects? / Shor, Dana; Sathyapalan, Thozhukat; Atkin, Stephen; Thatcher, Natalie J.

In: European Journal of Nutrition, Vol. 51, No. 4, 06.2012, p. 389-398.

Research output: Contribution to journalReview article

Shor, Dana ; Sathyapalan, Thozhukat ; Atkin, Stephen ; Thatcher, Natalie J. / Does Equol production determine soy endocrine effects?. In: European Journal of Nutrition. 2012 ; Vol. 51, No. 4. pp. 389-398.
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