Diversity in polyp pathology and distribution in familial juvenile polyposis syndrome

Tareq M. Al-Jaberi, Hatem El-Shanti

    Research output: Contribution to journalArticle

    4 Citations (Scopus)

    Abstract

    Objective: Juvenile polyposis syndrome is a rare autosomal dominant disorder with incomplete penetrance. The aim of this study was to review our experience with juvenile polyposis syndrome with emphasis on the diversity of polyp pathology and distribution and the recommended treatment. Methods: Over the period January 1994 through February 2001, 10 family members were managed at Princess Basma Teaching Hospital, Irbid, Jordan. Two siblings with juvenile polyposis syndrome are discussed. Results: The polyps were unusually concentrated in the rectum. In one patient the polyps were purely of the adenomatous type. The father suffered from non-polyposis colon cancer at the age of 35. Conclusion: Proctocolectomy and ileal pouch-anal anastomosis is recommended as the treatment of choice. Screening of juvenile polyposis syndrome patients and their relatives is emphasized for early detection of malignancy.

    Original languageEnglish
    Pages (from-to)328-331
    Number of pages4
    JournalSaudi Medical Journal
    Volume23
    Issue number3
    Publication statusPublished - 22 Apr 2002

      Fingerprint

    Keywords

    • Colon cancer
    • Hereditary mixed polyposis syndrome
    • Juvenile polyposis syndrome
    • Polyposis

    ASJC Scopus subject areas

    • Medicine(all)

    Cite this