Diversity in polyp pathology and distribution in familial juvenile polyposis syndrome

Tareq M. Al-Jaberi, Hatem El-Shanti

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: Juvenile polyposis syndrome is a rare autosomal dominant disorder with incomplete penetrance. The aim of this study was to review our experience with juvenile polyposis syndrome with emphasis on the diversity of polyp pathology and distribution and the recommended treatment. Methods: Over the period January 1994 through February 2001, 10 family members were managed at Princess Basma Teaching Hospital, Irbid, Jordan. Two siblings with juvenile polyposis syndrome are discussed. Results: The polyps were unusually concentrated in the rectum. In one patient the polyps were purely of the adenomatous type. The father suffered from non-polyposis colon cancer at the age of 35. Conclusion: Proctocolectomy and ileal pouch-anal anastomosis is recommended as the treatment of choice. Screening of juvenile polyposis syndrome patients and their relatives is emphasized for early detection of malignancy.

Original languageEnglish
Pages (from-to)328-331
Number of pages4
JournalSaudi Medical Journal
Volume23
Issue number3
Publication statusPublished - 2002
Externally publishedYes

Fingerprint

Adenomatous Polyposis Coli
Polyps
Pathology
Colonic Pouches
Jordan
Penetrance
Rectum
Teaching Hospitals
Fathers
Colonic Neoplasms
Siblings
Juvenile polyposis syndrome
Therapeutics
Neoplasms

Keywords

  • Colon cancer
  • Hereditary mixed polyposis syndrome
  • Juvenile polyposis syndrome
  • Polyposis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Diversity in polyp pathology and distribution in familial juvenile polyposis syndrome. / Al-Jaberi, Tareq M.; El-Shanti, Hatem.

In: Saudi Medical Journal, Vol. 23, No. 3, 2002, p. 328-331.

Research output: Contribution to journalArticle

Al-Jaberi, Tareq M. ; El-Shanti, Hatem. / Diversity in polyp pathology and distribution in familial juvenile polyposis syndrome. In: Saudi Medical Journal. 2002 ; Vol. 23, No. 3. pp. 328-331.
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