Diabetic neuropathy and painful diabetic neuropathy in the Middle East and North Africa (MENA) region: Much work needs to be done

Ioannis N. Petropoulos, Saad Javed, Shazli Azmi, Adnan Khan, Georgios Ponirakis, Rayaz Malik

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

The prevalence of diabetic peripheral neuropathy and painful diabetic peripheral neuropathy in the Middle East shows huge variability. This reflects the differing diagnostic techniques employed to diagnose neuropathy, but also the heterogeneity of the populations studied and the selection of populations from primary and secondary care. The treatment of diabetic neuropathy per se is inadequate as reflected by the poor control of risk factors such as glucose control, blood pressure and lipids in this region, which translates into the high rates of foot ulceration and amputation. In relation to symptomatic treatment, recommendations based on trials conducted in the West are without question, endorsed for the treatment of populations in the Middle East. Surely the demographics and patient responses both in terms of efficacy and side effects differ and therefore warrant local clinical trials. There is an over reliance on the prescription of B vitamins with the claim that they induce nerve repair. Whilst there is evidence for the relief of neuropathic symptoms with both vitamin B and D, again clinical trials are required in this region to establish their role in the treatment of diabetic neuropathy and painful diabetic neuropathy.

Original languageEnglish
Pages (from-to)284-294
Number of pages11
JournalJournal of Taibah University Medical Sciences
Volume11
Issue number4
DOIs
Publication statusPublished - 1 Aug 2016

Fingerprint

Northern Africa
Eastern Africa
Middle East
Diabetic Neuropathies
Peripheral Nervous System Diseases
Clinical Trials
Secondary Care
Vitamin B Complex
Population Characteristics
Therapeutics
Amputation
Vitamin D
Population
Prescriptions
Foot
Primary Health Care
Demography
Blood Pressure
Lipids
Glucose

Keywords

  • Arab world
  • Diabetic neuropathy
  • MENA
  • Painful diabetic neuropathy
  • Vitamin D

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Diabetic neuropathy and painful diabetic neuropathy in the Middle East and North Africa (MENA) region : Much work needs to be done. / Petropoulos, Ioannis N.; Javed, Saad; Azmi, Shazli; Khan, Adnan; Ponirakis, Georgios; Malik, Rayaz.

In: Journal of Taibah University Medical Sciences, Vol. 11, No. 4, 01.08.2016, p. 284-294.

Research output: Contribution to journalReview article

@article{430dc24837cd4b36a6b78bd5be86949a,
title = "Diabetic neuropathy and painful diabetic neuropathy in the Middle East and North Africa (MENA) region: Much work needs to be done",
abstract = "The prevalence of diabetic peripheral neuropathy and painful diabetic peripheral neuropathy in the Middle East shows huge variability. This reflects the differing diagnostic techniques employed to diagnose neuropathy, but also the heterogeneity of the populations studied and the selection of populations from primary and secondary care. The treatment of diabetic neuropathy per se is inadequate as reflected by the poor control of risk factors such as glucose control, blood pressure and lipids in this region, which translates into the high rates of foot ulceration and amputation. In relation to symptomatic treatment, recommendations based on trials conducted in the West are without question, endorsed for the treatment of populations in the Middle East. Surely the demographics and patient responses both in terms of efficacy and side effects differ and therefore warrant local clinical trials. There is an over reliance on the prescription of B vitamins with the claim that they induce nerve repair. Whilst there is evidence for the relief of neuropathic symptoms with both vitamin B and D, again clinical trials are required in this region to establish their role in the treatment of diabetic neuropathy and painful diabetic neuropathy.",
keywords = "Arab world, Diabetic neuropathy, MENA, Painful diabetic neuropathy, Vitamin D",
author = "Petropoulos, {Ioannis N.} and Saad Javed and Shazli Azmi and Adnan Khan and Georgios Ponirakis and Rayaz Malik",
year = "2016",
month = "8",
day = "1",
doi = "10.1016/j.jtumed.2016.06.002",
language = "English",
volume = "11",
pages = "284--294",
journal = "Journal of Taibah University Medical Sciences",
issn = "1658-3612",
publisher = "Elsevier BV",
number = "4",

}

TY - JOUR

T1 - Diabetic neuropathy and painful diabetic neuropathy in the Middle East and North Africa (MENA) region

T2 - Much work needs to be done

AU - Petropoulos, Ioannis N.

AU - Javed, Saad

AU - Azmi, Shazli

AU - Khan, Adnan

AU - Ponirakis, Georgios

AU - Malik, Rayaz

PY - 2016/8/1

Y1 - 2016/8/1

N2 - The prevalence of diabetic peripheral neuropathy and painful diabetic peripheral neuropathy in the Middle East shows huge variability. This reflects the differing diagnostic techniques employed to diagnose neuropathy, but also the heterogeneity of the populations studied and the selection of populations from primary and secondary care. The treatment of diabetic neuropathy per se is inadequate as reflected by the poor control of risk factors such as glucose control, blood pressure and lipids in this region, which translates into the high rates of foot ulceration and amputation. In relation to symptomatic treatment, recommendations based on trials conducted in the West are without question, endorsed for the treatment of populations in the Middle East. Surely the demographics and patient responses both in terms of efficacy and side effects differ and therefore warrant local clinical trials. There is an over reliance on the prescription of B vitamins with the claim that they induce nerve repair. Whilst there is evidence for the relief of neuropathic symptoms with both vitamin B and D, again clinical trials are required in this region to establish their role in the treatment of diabetic neuropathy and painful diabetic neuropathy.

AB - The prevalence of diabetic peripheral neuropathy and painful diabetic peripheral neuropathy in the Middle East shows huge variability. This reflects the differing diagnostic techniques employed to diagnose neuropathy, but also the heterogeneity of the populations studied and the selection of populations from primary and secondary care. The treatment of diabetic neuropathy per se is inadequate as reflected by the poor control of risk factors such as glucose control, blood pressure and lipids in this region, which translates into the high rates of foot ulceration and amputation. In relation to symptomatic treatment, recommendations based on trials conducted in the West are without question, endorsed for the treatment of populations in the Middle East. Surely the demographics and patient responses both in terms of efficacy and side effects differ and therefore warrant local clinical trials. There is an over reliance on the prescription of B vitamins with the claim that they induce nerve repair. Whilst there is evidence for the relief of neuropathic symptoms with both vitamin B and D, again clinical trials are required in this region to establish their role in the treatment of diabetic neuropathy and painful diabetic neuropathy.

KW - Arab world

KW - Diabetic neuropathy

KW - MENA

KW - Painful diabetic neuropathy

KW - Vitamin D

UR - http://www.scopus.com/inward/record.url?scp=84979010888&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84979010888&partnerID=8YFLogxK

U2 - 10.1016/j.jtumed.2016.06.002

DO - 10.1016/j.jtumed.2016.06.002

M3 - Review article

AN - SCOPUS:84979010888

VL - 11

SP - 284

EP - 294

JO - Journal of Taibah University Medical Sciences

JF - Journal of Taibah University Medical Sciences

SN - 1658-3612

IS - 4

ER -