Curcumin in heart failure

A choice for complementary therapy?

Amin Saeidinia, Faeze Keihanian, Alexandra E. Butler, Ramin Khameneh Bagheri, Stephen Atkin, Amirhossein Sahebkar

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Heart failure is a major public health concern and one of the most common reasons for a cardiac hospital admission. Heart failure may be classified as having a reduced or preserved ejection fraction and its severity is based on the symptom score. Given the aging population, it is predicted that admissions with heart failure will increase. Whilst pharmacological therapy has improved the associated morbidity and mortality, there is a need for additional therapies to improve the clinical outcome as the death rate remains high. Curcumin is a natural product derived from turmeric that appears to have cardiovascular benefit through a number of mechanisms. In this review, we have assessed the mechanisms by which curcumin may exert its effects in different models of heart failure and show that it has promise as a complementary treatment in heart failure.

Original languageEnglish
Pages (from-to)112-119
Number of pages8
JournalPharmacological Research
Volume131
DOIs
Publication statusPublished - 1 May 2018

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Curcumin
Complementary Therapies
Heart Failure
Curcuma
Mortality
Biological Products
Therapeutics
Public Health
Pharmacology
Morbidity
Population

Keywords

  • Cardiovascular disorders
  • Complementary medicine
  • Curcumin
  • Heart failure

ASJC Scopus subject areas

  • Pharmacology

Cite this

Saeidinia, A., Keihanian, F., Butler, A. E., Bagheri, R. K., Atkin, S., & Sahebkar, A. (2018). Curcumin in heart failure: A choice for complementary therapy? Pharmacological Research, 131, 112-119. https://doi.org/10.1016/j.phrs.2018.03.009

Curcumin in heart failure : A choice for complementary therapy? / Saeidinia, Amin; Keihanian, Faeze; Butler, Alexandra E.; Bagheri, Ramin Khameneh; Atkin, Stephen; Sahebkar, Amirhossein.

In: Pharmacological Research, Vol. 131, 01.05.2018, p. 112-119.

Research output: Contribution to journalReview article

Saeidinia, A, Keihanian, F, Butler, AE, Bagheri, RK, Atkin, S & Sahebkar, A 2018, 'Curcumin in heart failure: A choice for complementary therapy?', Pharmacological Research, vol. 131, pp. 112-119. https://doi.org/10.1016/j.phrs.2018.03.009
Saeidinia, Amin ; Keihanian, Faeze ; Butler, Alexandra E. ; Bagheri, Ramin Khameneh ; Atkin, Stephen ; Sahebkar, Amirhossein. / Curcumin in heart failure : A choice for complementary therapy?. In: Pharmacological Research. 2018 ; Vol. 131. pp. 112-119.
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