Cross-Validation of the Arabic Mini International Neuropsychiatric Interview, Module K, for Diagnosis of Schizophrenia and the Arabic Positive and Negative Syndrome Scale

Rifka Chamali, Suhaila Ghuloum, David V. Sheehan, Ziyad Mahfoud, Arij Yehya, Mark G.A. Opler, Anzalee Khan, Samer Hammoudeh, Yahya Hani, Hassen Al Amin

Research output: Contribution to journalArticle

Abstract

The Mini International Neuropsychiatric Interview, version 6, module K (MINI6-Mod-K) is a diagnostic tool to confirm schizophrenia; whereas the Positive and Negative Syndrome Scale in Schizophrenia (PANSS) is a scale to assess psychotic symptoms severity. The objective of this study was to cross-validate the diagnostic questions (categorical) from the Arabic MINI6-Mod-K with the corresponding items’ scores (dimensional) from Arabic PANSS. Arab subjects (N = 101) were recruited from the Psychiatry Hospital in Qatar. MINI6-Mod-K was used to confirm schizophrenia diagnosis, and PANSS was administered to assess psychopathology by an independent rater. The most common symptoms according to MINI6-Mod-K were the delusions and hallucinations but the PANSS items scores ≥2.5 captured more positive responses on all the diagnostic features of schizophrenia. The cut-off PANSS scores that significantly distinguished between the presence or absence of schizophrenia features on MINI6-Mod-K were mostly between 2.5 and 3.5. Multivariate linear regression showed that negative symptoms and disorganized/catatonic behaviors independently contributed to the PANSS score on positive symptoms subscale. However, none of the symptom questions in the MINI6-Mod-K were significant predictors of the PANSS negative score. Our results showed that there is very good cross-validation between the diagnostic questions of Arabic MINI6-Mod-K and the corresponding positive cut-off scores in Arabic PANSS.

Original languageEnglish
JournalJournal of Psychopathology and Behavioral Assessment
DOIs
Publication statusAccepted/In press - 1 Jan 2019

Fingerprint

Schizophrenia
Interviews
Qatar
Delusions
Hallucinations
Psychopathology
Psychiatry
Linear Models

Keywords

  • Arabic MINI6
  • Arabic PANSS
  • Psychopathology
  • Schizophrenia

ASJC Scopus subject areas

  • Clinical Psychology

Cite this

Cross-Validation of the Arabic Mini International Neuropsychiatric Interview, Module K, for Diagnosis of Schizophrenia and the Arabic Positive and Negative Syndrome Scale. / Chamali, Rifka; Ghuloum, Suhaila; Sheehan, David V.; Mahfoud, Ziyad; Yehya, Arij; Opler, Mark G.A.; Khan, Anzalee; Hammoudeh, Samer; Hani, Yahya; Al Amin, Hassen.

In: Journal of Psychopathology and Behavioral Assessment, 01.01.2019.

Research output: Contribution to journalArticle

Chamali, Rifka ; Ghuloum, Suhaila ; Sheehan, David V. ; Mahfoud, Ziyad ; Yehya, Arij ; Opler, Mark G.A. ; Khan, Anzalee ; Hammoudeh, Samer ; Hani, Yahya ; Al Amin, Hassen. / Cross-Validation of the Arabic Mini International Neuropsychiatric Interview, Module K, for Diagnosis of Schizophrenia and the Arabic Positive and Negative Syndrome Scale. In: Journal of Psychopathology and Behavioral Assessment. 2019.
@article{b308328072cb4030b834b148f53aee94,
title = "Cross-Validation of the Arabic Mini International Neuropsychiatric Interview, Module K, for Diagnosis of Schizophrenia and the Arabic Positive and Negative Syndrome Scale",
abstract = "The Mini International Neuropsychiatric Interview, version 6, module K (MINI6-Mod-K) is a diagnostic tool to confirm schizophrenia; whereas the Positive and Negative Syndrome Scale in Schizophrenia (PANSS) is a scale to assess psychotic symptoms severity. The objective of this study was to cross-validate the diagnostic questions (categorical) from the Arabic MINI6-Mod-K with the corresponding items’ scores (dimensional) from Arabic PANSS. Arab subjects (N = 101) were recruited from the Psychiatry Hospital in Qatar. MINI6-Mod-K was used to confirm schizophrenia diagnosis, and PANSS was administered to assess psychopathology by an independent rater. The most common symptoms according to MINI6-Mod-K were the delusions and hallucinations but the PANSS items scores ≥2.5 captured more positive responses on all the diagnostic features of schizophrenia. The cut-off PANSS scores that significantly distinguished between the presence or absence of schizophrenia features on MINI6-Mod-K were mostly between 2.5 and 3.5. Multivariate linear regression showed that negative symptoms and disorganized/catatonic behaviors independently contributed to the PANSS score on positive symptoms subscale. However, none of the symptom questions in the MINI6-Mod-K were significant predictors of the PANSS negative score. Our results showed that there is very good cross-validation between the diagnostic questions of Arabic MINI6-Mod-K and the corresponding positive cut-off scores in Arabic PANSS.",
keywords = "Arabic MINI6, Arabic PANSS, Psychopathology, Schizophrenia",
author = "Rifka Chamali and Suhaila Ghuloum and Sheehan, {David V.} and Ziyad Mahfoud and Arij Yehya and Opler, {Mark G.A.} and Anzalee Khan and Samer Hammoudeh and Yahya Hani and {Al Amin}, Hassen",
year = "2019",
month = "1",
day = "1",
doi = "10.1007/s10862-019-09759-6",
language = "English",
journal = "Journal of Psychopathology and Behavioral Assessment",
issn = "0882-2689",
publisher = "Springer New York",

}

TY - JOUR

T1 - Cross-Validation of the Arabic Mini International Neuropsychiatric Interview, Module K, for Diagnosis of Schizophrenia and the Arabic Positive and Negative Syndrome Scale

AU - Chamali, Rifka

AU - Ghuloum, Suhaila

AU - Sheehan, David V.

AU - Mahfoud, Ziyad

AU - Yehya, Arij

AU - Opler, Mark G.A.

AU - Khan, Anzalee

AU - Hammoudeh, Samer

AU - Hani, Yahya

AU - Al Amin, Hassen

PY - 2019/1/1

Y1 - 2019/1/1

N2 - The Mini International Neuropsychiatric Interview, version 6, module K (MINI6-Mod-K) is a diagnostic tool to confirm schizophrenia; whereas the Positive and Negative Syndrome Scale in Schizophrenia (PANSS) is a scale to assess psychotic symptoms severity. The objective of this study was to cross-validate the diagnostic questions (categorical) from the Arabic MINI6-Mod-K with the corresponding items’ scores (dimensional) from Arabic PANSS. Arab subjects (N = 101) were recruited from the Psychiatry Hospital in Qatar. MINI6-Mod-K was used to confirm schizophrenia diagnosis, and PANSS was administered to assess psychopathology by an independent rater. The most common symptoms according to MINI6-Mod-K were the delusions and hallucinations but the PANSS items scores ≥2.5 captured more positive responses on all the diagnostic features of schizophrenia. The cut-off PANSS scores that significantly distinguished between the presence or absence of schizophrenia features on MINI6-Mod-K were mostly between 2.5 and 3.5. Multivariate linear regression showed that negative symptoms and disorganized/catatonic behaviors independently contributed to the PANSS score on positive symptoms subscale. However, none of the symptom questions in the MINI6-Mod-K were significant predictors of the PANSS negative score. Our results showed that there is very good cross-validation between the diagnostic questions of Arabic MINI6-Mod-K and the corresponding positive cut-off scores in Arabic PANSS.

AB - The Mini International Neuropsychiatric Interview, version 6, module K (MINI6-Mod-K) is a diagnostic tool to confirm schizophrenia; whereas the Positive and Negative Syndrome Scale in Schizophrenia (PANSS) is a scale to assess psychotic symptoms severity. The objective of this study was to cross-validate the diagnostic questions (categorical) from the Arabic MINI6-Mod-K with the corresponding items’ scores (dimensional) from Arabic PANSS. Arab subjects (N = 101) were recruited from the Psychiatry Hospital in Qatar. MINI6-Mod-K was used to confirm schizophrenia diagnosis, and PANSS was administered to assess psychopathology by an independent rater. The most common symptoms according to MINI6-Mod-K were the delusions and hallucinations but the PANSS items scores ≥2.5 captured more positive responses on all the diagnostic features of schizophrenia. The cut-off PANSS scores that significantly distinguished between the presence or absence of schizophrenia features on MINI6-Mod-K were mostly between 2.5 and 3.5. Multivariate linear regression showed that negative symptoms and disorganized/catatonic behaviors independently contributed to the PANSS score on positive symptoms subscale. However, none of the symptom questions in the MINI6-Mod-K were significant predictors of the PANSS negative score. Our results showed that there is very good cross-validation between the diagnostic questions of Arabic MINI6-Mod-K and the corresponding positive cut-off scores in Arabic PANSS.

KW - Arabic MINI6

KW - Arabic PANSS

KW - Psychopathology

KW - Schizophrenia

UR - http://www.scopus.com/inward/record.url?scp=85071750496&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071750496&partnerID=8YFLogxK

U2 - 10.1007/s10862-019-09759-6

DO - 10.1007/s10862-019-09759-6

M3 - Article

AN - SCOPUS:85071750496

JO - Journal of Psychopathology and Behavioral Assessment

JF - Journal of Psychopathology and Behavioral Assessment

SN - 0882-2689

ER -