Correlating 2D histological slice with 3D MRI image volume using smart phone as an interactive tool for muscle study

Aydin Eresen, Peng Li, Jim Ji

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

In muscle dystrophy studies, registration of histological image with MRI image volume enables cross validation of MRI biomarkers using pathological result. However, correlation of 2D histology slice with 3D MRI volume is technically challenging due to the potentially non-orthogonal slice plane and incomplete or distorted histological slice. This paper presents an efficient method to directly perform the 2D-3D registration. The method is unique in that it uses smart phone as a navigation tool for initial alignment followed by an overlap invariant mutual information-based refinement. Experimental results using animal muscle samples images from a 3T MRI and HE stained histological images show that the proposed method is capable of aligning the histological slice with an oblique slice in MR volume.

Original languageEnglish
Title of host publication2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages6418-6421
Number of pages4
ISBN (Electronic)9781424479290
DOIs
Publication statusPublished - 2 Nov 2014
Externally publishedYes
Event2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, United States
Duration: 26 Aug 201430 Aug 2014

Other

Other2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
CountryUnited States
CityChicago
Period26/8/1430/8/14

Fingerprint

Magnetic resonance imaging
Muscle
Muscles
Histology
Biomarkers
Animals
Navigation
Smartphone

ASJC Scopus subject areas

  • Health Informatics
  • Computer Science Applications
  • Biomedical Engineering

Cite this

Eresen, A., Li, P., & Ji, J. (2014). Correlating 2D histological slice with 3D MRI image volume using smart phone as an interactive tool for muscle study. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 (pp. 6418-6421). [6945097] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2014.6945097

Correlating 2D histological slice with 3D MRI image volume using smart phone as an interactive tool for muscle study. / Eresen, Aydin; Li, Peng; Ji, Jim.

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc., 2014. p. 6418-6421 6945097.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Eresen, A, Li, P & Ji, J 2014, Correlating 2D histological slice with 3D MRI image volume using smart phone as an interactive tool for muscle study. in 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014., 6945097, Institute of Electrical and Electronics Engineers Inc., pp. 6418-6421, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, Chicago, United States, 26/8/14. https://doi.org/10.1109/EMBC.2014.6945097
Eresen A, Li P, Ji J. Correlating 2D histological slice with 3D MRI image volume using smart phone as an interactive tool for muscle study. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc. 2014. p. 6418-6421. 6945097 https://doi.org/10.1109/EMBC.2014.6945097
Eresen, Aydin ; Li, Peng ; Ji, Jim. / Correlating 2D histological slice with 3D MRI image volume using smart phone as an interactive tool for muscle study. 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc., 2014. pp. 6418-6421
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