Computer analysis of EEG activity in dementia of the Alzheimer's type and Huntington's disease

Leopold Streletz, Patricio F. Reyes, Margaret Zalewska, Leonard Katz, Ruggero G. Fariello

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50 Citations (Scopus)

Abstract

Computer analysis of the EEG was obtained in the course of evaluation of 35 patients with Dementia of the Alzheimer's Type (DAT) and Huntington's disease (HD), and compared to 20 age-matched normal controls. On-line computer analysis of the EEG consisted of: 1) compressed spectral array (CSA) displays (2-6 channels); 2) relative frequency power (4 bands) and 3) an averaged frequency power function {[alpha/alpha + theta power (μV2)] × 100 = % EEG Power function}. Frequency power reflected increased theta, and reduced alpha components, in patient groups. Significant correlation was obtained between % EEG Power function, and clinical stage of dementia. This function correctly identified 17/25 DAT, and 7/10 HD patients, and gave additional quantification to the primary EEG.

Original languageEnglish
Pages (from-to)15-20
Number of pages6
JournalNeurobiology of Aging
Volume11
Issue number1
DOIs
Publication statusPublished - 1990
Externally publishedYes

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Keywords

  • Alzheimer's disease
  • Computer analysis
  • Dementia
  • EEG
  • EEG power
  • Huntington's disease

ASJC Scopus subject areas

  • Neuroscience(all)
  • Ageing
  • Developmental Biology
  • Geriatrics and Gerontology
  • Clinical Neurology

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