Computational fluid–structure interaction analysis of blood flow on patient-specific reconstructed aortic anatomy and aneurysm treatment with Dacron graft

Raja Jayendiran, Bakr Nour, Annie Ruimi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We use the fluid–structure interaction (FSI) capability in Abaqus to evaluate radial displacements, von Mises stresses and wall shear stresses (WSS) on the human aorta in response to the blood flowing through it. Complications arise when aneurysm is detected and causes the wall to thinner so much that rupture may result. We use the Materialise suite, a specialty software to reconstruct a three-dimensional geometry of the aorta from two-dimensional computerized axial tomography (CAT) images. Results are compared to those obtained on a healthy individual. Blood is assumed to be a Newtonian and incompressible medium and the blood flow is taken as pulsatile, fully developed and turbulent. The model used for aorta is Holzapfel–Gasser–Ogden (HGO), a sophisticated hyperelastic model that can describe biological tissues. We also study the behavior of Dacron, a polyester fabric used as graft in aortic surgical repair. Here, Dacron is represented by a neo-Hookean (isotropic) hyperelastic model. Time-dependent pressure conditions are assumed at the inlet and outlet of the resulting structure. Results indicate that using a patient-specific geometry for the aorta yields additional insight on the state of the stresses applied on the aortic walls. In addition, stress contours on the Dacron are comparable to those obtained on a healthy patient and stresses evaluated at the interface of the biological tissues and the fabric, provide useful information regarding the suture strength needed during surgery. In the case of aneurysm, our simulation results agree well with experimental data taken from the literature particularly with regard to WSS which can be used to assess the seriousness of the aneurysm condition. If an idealized cylindrical shell is used in place of the reconstructed anatomy, the von Mises stress values do not differ much but it underestimates the values of WSS which could interpreted as the presence of an aneurysm when there is not. Among the novel contributions, the present FSI model has the ability to predict the Dacron's response to realistic hemodynamic loading conditions.

Original languageEnglish
Pages (from-to)693-711
Number of pages19
JournalJournal of Fluids and Structures
Volume81
DOIs
Publication statusPublished - 1 Aug 2018

Fingerprint

Grafts
Blood
Shear stress
Tissue
Geometry
Hemodynamics
Surgery
Tomography
Polyesters
Repair

Keywords

  • Dacron graft
  • Fluid–structure interaction
  • Hyperelastic
  • Patient-specific aortic anatomy
  • Wall shear stress

ASJC Scopus subject areas

  • Mechanical Engineering

Cite this

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title = "Computational fluid–structure interaction analysis of blood flow on patient-specific reconstructed aortic anatomy and aneurysm treatment with Dacron graft",
abstract = "We use the fluid–structure interaction (FSI) capability in Abaqus to evaluate radial displacements, von Mises stresses and wall shear stresses (WSS) on the human aorta in response to the blood flowing through it. Complications arise when aneurysm is detected and causes the wall to thinner so much that rupture may result. We use the Materialise suite, a specialty software to reconstruct a three-dimensional geometry of the aorta from two-dimensional computerized axial tomography (CAT) images. Results are compared to those obtained on a healthy individual. Blood is assumed to be a Newtonian and incompressible medium and the blood flow is taken as pulsatile, fully developed and turbulent. The model used for aorta is Holzapfel–Gasser–Ogden (HGO), a sophisticated hyperelastic model that can describe biological tissues. We also study the behavior of Dacron, a polyester fabric used as graft in aortic surgical repair. Here, Dacron is represented by a neo-Hookean (isotropic) hyperelastic model. Time-dependent pressure conditions are assumed at the inlet and outlet of the resulting structure. Results indicate that using a patient-specific geometry for the aorta yields additional insight on the state of the stresses applied on the aortic walls. In addition, stress contours on the Dacron are comparable to those obtained on a healthy patient and stresses evaluated at the interface of the biological tissues and the fabric, provide useful information regarding the suture strength needed during surgery. In the case of aneurysm, our simulation results agree well with experimental data taken from the literature particularly with regard to WSS which can be used to assess the seriousness of the aneurysm condition. If an idealized cylindrical shell is used in place of the reconstructed anatomy, the von Mises stress values do not differ much but it underestimates the values of WSS which could interpreted as the presence of an aneurysm when there is not. Among the novel contributions, the present FSI model has the ability to predict the Dacron's response to realistic hemodynamic loading conditions.",
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AB - We use the fluid–structure interaction (FSI) capability in Abaqus to evaluate radial displacements, von Mises stresses and wall shear stresses (WSS) on the human aorta in response to the blood flowing through it. Complications arise when aneurysm is detected and causes the wall to thinner so much that rupture may result. We use the Materialise suite, a specialty software to reconstruct a three-dimensional geometry of the aorta from two-dimensional computerized axial tomography (CAT) images. Results are compared to those obtained on a healthy individual. Blood is assumed to be a Newtonian and incompressible medium and the blood flow is taken as pulsatile, fully developed and turbulent. The model used for aorta is Holzapfel–Gasser–Ogden (HGO), a sophisticated hyperelastic model that can describe biological tissues. We also study the behavior of Dacron, a polyester fabric used as graft in aortic surgical repair. Here, Dacron is represented by a neo-Hookean (isotropic) hyperelastic model. Time-dependent pressure conditions are assumed at the inlet and outlet of the resulting structure. Results indicate that using a patient-specific geometry for the aorta yields additional insight on the state of the stresses applied on the aortic walls. In addition, stress contours on the Dacron are comparable to those obtained on a healthy patient and stresses evaluated at the interface of the biological tissues and the fabric, provide useful information regarding the suture strength needed during surgery. In the case of aneurysm, our simulation results agree well with experimental data taken from the literature particularly with regard to WSS which can be used to assess the seriousness of the aneurysm condition. If an idealized cylindrical shell is used in place of the reconstructed anatomy, the von Mises stress values do not differ much but it underestimates the values of WSS which could interpreted as the presence of an aneurysm when there is not. Among the novel contributions, the present FSI model has the ability to predict the Dacron's response to realistic hemodynamic loading conditions.

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