Composite template membranes as synthetic receptor systems 1. Preparation, specificity and template effect

V. M. Kochkodan, V. V. Honcharuk

Research output: Contribution to journalArticle

Abstract

Molecularly impregnated membranes for selective recognizing of adenosine 3',5'-cyclic monophosphate (cAMP) were obtained and their separation properties were studied. Composite polyvinylidenfluoride microfiltration membranes covered with a thin layer of polymer impregnated with cAMP were prepared using photoinitiated copolymerization of dimethylaminoethylmethacrylate as a functional monomer and trimethylolpropane thrimethacrylate as a cross-linker in the presence of cAMP as a template. It was concluded that the ability of MIP membranes to selective binding of cAMP is a result of both specific shape and dimension of the recognizing site as well as specific interactions between functional groups responsible for selective template binding inside the receptor site.

Original languageEnglish
Pages (from-to)99-104
Number of pages6
JournalUkrainski¿ biokhimicheski¿ zhurnal.
Volume77
Issue number2
Publication statusPublished - 1 Mar 2005

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ASJC Scopus subject areas

  • Biochemistry

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