Comparative evaluation of hexokinase isoenzyme typing and antigen detection for differentiation of Entamoeba histolytica and Entamoeba dispar.

Devendra Bansal, Rakesh Sehgal, Yogesh Chawla, Ramesh Chander Mahajan, Nancy Malla

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Abstract

Entamoeba histolytica, the causative organism of invasive amebiasis is a potential pathogen, while asymptomatic infection is caused by E. dispar. Differentiation of the species is not possible on the basis of morphological characters by microscopic examination. In the present study an attempt has been made to differentiate E. histolytica from E. dispar in 45 isolates obtained from culture and direct stool samples respectively on the basis of hexokinase isoenzyme analysis and Tech Lab ELISA. A 100% correlation was found between these two techniques. However, Tech Lab E. histolytica antigen detection test was found to be both rapid and technically simple. Its use in diagnosis and epidemiological studies is recommended.

Original languageEnglish
Pages (from-to)123-125
Number of pages3
JournalNepal Medical College journal : NMCJ
Volume6
Issue number2
Publication statusPublished - Dec 2004

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ASJC Scopus subject areas

  • Medicine(all)

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