Cloning, expression, and mapping of PDCD9, the human homolog of Gallus gallus pro-apoptotic protein p52

L. Carim, L. Sumoy, M. Nadal, Xavier P. Estivill, Mònica Escarceller

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

We report the sequence, tissue distribution, and chromosome location of a novel gene, PDCD9 (programmed cell death 9). PDCD9 is the mammalian counterpart of the Gallus gallus pro-apoptotic protein p52. The human cDNA has an open reading frame of 1314 nucleotides and was predicted to encode a protein of 438 amino acids with a calculated mass of 50 kDa. The protein sequences of chicken, mouse, and human PDCD9 are remarkably conserved. PDCD9 mRNA is expressed ubiquitously in adult tissues, displaying a stronger signal in heart, skeletal muscle, kidney, and liver. PDCD9 was mapped to chromosome 5q11.

Original languageEnglish
Pages (from-to)85-88
Number of pages4
JournalCytogenetics and Cell Genetics
Volume87
Issue number1-2
Publication statusPublished - 1999
Externally publishedYes

Fingerprint

Apoptosis Regulatory Proteins
Organism Cloning
Chickens
Cell Death
Chromosomes
Tissue Distribution
Open Reading Frames
Myocardium
Skeletal Muscle
Proteins
Nucleotides
Complementary DNA
Kidney
Amino Acids
Messenger RNA
Liver
Genes

ASJC Scopus subject areas

  • Genetics
  • Cell Biology

Cite this

Cloning, expression, and mapping of PDCD9, the human homolog of Gallus gallus pro-apoptotic protein p52. / Carim, L.; Sumoy, L.; Nadal, M.; Estivill, Xavier P.; Escarceller, Mònica.

In: Cytogenetics and Cell Genetics, Vol. 87, No. 1-2, 1999, p. 85-88.

Research output: Contribution to journalArticle

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