Chromosome assignment and restriction fragment length polymorphism analysis of the anonymous DNA probe B79a at 7q22 (HMG8 assignment D7S13)

Xavier P. Estivill, J. Schmidtke, R. Williamson, B. Wainwright

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The anonymous DNA fragment B79a, which had previously been located to chromosome 7cen-7q22, has been more accurately assigned to 7q22 by dosage analysis in a patient hemizygous for a deletion of that region. By examination of a panel of genomic DNAs from unrelated individuals, digested with a number of different restriction enzymes, we have identified two frequent RFLPs detected by B79a. This probe will be important in the analysis of cystic fibrosis which has been mapped to the region around 7q22.

Original languageEnglish
Pages (from-to)320-322
Number of pages3
JournalHuman Genetics
Volume74
Issue number3
DOIs
Publication statusPublished - Nov 1986
Externally publishedYes

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DNA Probes
Restriction Fragment Length Polymorphisms
Chromosomes
DNA
Cystic Fibrosis
Enzymes

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Cite this

Chromosome assignment and restriction fragment length polymorphism analysis of the anonymous DNA probe B79a at 7q22 (HMG8 assignment D7S13). / Estivill, Xavier P.; Schmidtke, J.; Williamson, R.; Wainwright, B.

In: Human Genetics, Vol. 74, No. 3, 11.1986, p. 320-322.

Research output: Contribution to journalArticle

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