Chloride removal selectively inhibits phasic contractions of guinea pig ileal longitudinal smooth muscle

P. K. Rangachari, C. R. Triggle, E. E. Daniel

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Abstract

Removal of external chloride selectively and reversibly inhibits the phasic responses of the guinea pig ileal longitudinal muscle to high potassium and cholinergic stimulation. The binding of calcium to a relatively superficial pool is affected by chloride removal. Alterations in anionic composition of bathing solution affects the availability of calcium for excitation-contraction (E-C) coupling a smooth muscle.

Original languageEnglish
Pages (from-to)1741-1744
Number of pages4
JournalCanadian Journal of Physiology and Pharmacology
Volume60
Issue number12
DOIs
Publication statusPublished - 1 Jan 1982

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ASJC Scopus subject areas

  • Physiology
  • Pharmacology
  • Physiology (medical)

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