Chloride removal selectively inhibits phasic contractions of guinea pig ileal longitudinal smooth muscle

P. K. Rangachari, Christopher Triggle, E. E. Daniel

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Removal of external chloride selectively and reversibly inhibits the phasic responses of the guinea pig ileal longitudinal muscle to high potassium and cholinergic stimulation. The binding of calcium to a relatively superficial pool is affected by chloride removal. Alterations in anionic composition of bathing solution affects the availability of calcium for excitation-contraction (E-C) coupling a smooth muscle.

Original languageEnglish
Pages (from-to)1741-1744
Number of pages4
JournalCanadian Journal of Physiology and Pharmacology
Volume60
Issue number12
Publication statusPublished - 1982
Externally publishedYes

Fingerprint

Smooth Muscle
Chlorides
Guinea Pigs
Calcium
Excitation Contraction Coupling
Cholinergic Agents
Potassium
Muscles

ASJC Scopus subject areas

  • Physiology
  • Pharmacology

Cite this

Chloride removal selectively inhibits phasic contractions of guinea pig ileal longitudinal smooth muscle. / Rangachari, P. K.; Triggle, Christopher; Daniel, E. E.

In: Canadian Journal of Physiology and Pharmacology, Vol. 60, No. 12, 1982, p. 1741-1744.

Research output: Contribution to journalArticle

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