Ca2+ signaling differentiation during oocyte maturation

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Oocyte maturation is an essential cellular differentiation pathway that prepares the egg for activation at fertilization leading to the initiation of embryogenesis. An integral attribute of oocyte maturation is the remodeling of Ca2+ signaling pathways endowing the egg with the capacity to produce a specialized Ca2+ transient at fertilization that is necessary and sufficient for egg activation. Consequently, mechanistic elucidation of Ca 2+ signaling differentiation during oocyte maturation is fundamental to our understanding of egg activation, and offers a glimpse into Ca 2+ signaling regulation during the cell cycle.

Original languageEnglish
Pages (from-to)331-340
Number of pages10
JournalJournal of Cellular Physiology
Issue number2
Publication statusPublished - 1 Nov 2007


ASJC Scopus subject areas

  • Physiology
  • Clinical Biochemistry
  • Cell Biology

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