Breast cancer and reproductive history from genealogical data

Steven C. Hunt, Mark H. Skolnick

Research output: Contribution to journalArticle

24 Citations (Scopus)


With the use of data from the Utah State Cancer Registry and Utah genealogical data, an analysis of 236 breast cancer patients and 937 controls matched on year of birth showed that a late age at the birth of the first child was most strongly associated with incidence of breast cancer (relative odds=2.0; P`0.001). A strong interaction was found between age at first delivery (AFD) and age at last delivery (ALD). The association of AFD with breast cancer incidence was strongest for women with an ALD before 35 years of age even after adjustment for parity (relative odds=4.1; P`0.001). Decreased parity was not significantly associated with breast cancer.

Original languageEnglish
Pages (from-to)1047-1053
Number of pages7
JournalJournal of the National Cancer Institute
Issue number5
Publication statusPublished - May 1980


ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this