Breast cancer and reproductive history from genealogical data

Steven Hunt, Mark H. Skolnick

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

With the use of data from the Utah State Cancer Registry and Utah genealogical data, an analysis of 236 breast cancer patients and 937 controls matched on year of birth showed that a late age at the birth of the first child was most strongly associated with incidence of breast cancer (relative odds=2.0; P`0.001). A strong interaction was found between age at first delivery (AFD) and age at last delivery (ALD). The association of AFD with breast cancer incidence was strongest for women with an ALD before 35 years of age even after adjustment for parity (relative odds=4.1; P`0.001). Decreased parity was not significantly associated with breast cancer.

Original languageEnglish
Pages (from-to)1047-1053
Number of pages7
JournalJournal of the National Cancer Institute
Volume64
Issue number5
DOIs
Publication statusPublished - 1980
Externally publishedYes

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Reproductive History
Breast Neoplasms
Parity
Odds Ratio
Birth Order
Incidence
Registries
Parturition
Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Breast cancer and reproductive history from genealogical data. / Hunt, Steven; Skolnick, Mark H.

In: Journal of the National Cancer Institute, Vol. 64, No. 5, 1980, p. 1047-1053.

Research output: Contribution to journalArticle

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