Black-blood T2* mapping with delay alternating with nutation for tailored excitation

Shi Su, Yanan Ren, Caiyun Shi, Xiaoyong Zhang, Jim Ji, Yongqin Zhang, Xin Liu, Guoxi Xie

Research output: Contribution to journalArticle

1 Citation (Scopus)


Purpose To develop a black-blood T2* mapping method using a Delay Alternating with Nutation for Tailored Excitation (DANTE) preparation combined with a multi-echo gradient echo (GRE) readout (DANTE-GRE). Materials and methods Simulations of the Bloch equation for DANTE-GRE were performed to optimize sequence parameters. After optimization, the sequence was applied to a phantom scan and to neck and lower extremity scans conducted on 12 volunteers at 3 T using DANTE-GRE, Motion-Sensitized Driven Equilibrium (MSDE)-GRE, and multi-echo GRE. T2* values were measured using an offset model. Statistical analyses were conducted to compare the T2* values between the three sequences. Results Simulation results showed that blood suppression can be achieved with various DANTE parameter adjustments. T2* maps acquired by DANTE-GRE were consistent and comparable to those acquired with multi-echo GRE in phantom experiments. In the in vivo experiments, DANTE-GRE was more comparable to multi-echo GRE than MSDE-GRE regarding the measurement of muscle T2* values. Conclusion Due to its high signal intensity retention and effective blood signal suppression, DANTE-GRE allows for robust and accurate T2* quantification, superior to that of MSDE-GRE, while overcoming blood flow artifacts associated with traditional multi-echo GRE.

Original languageEnglish
Pages (from-to)91-97
Number of pages7
JournalMagnetic Resonance Imaging
Publication statusPublished - 1 Jul 2017
Externally publishedYes



  • black-blood
  • T2* mapping

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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