Banff '09 meeting report: Antibody mediated graft deterioration and implementation of Banff working groups

B. Sis, M. Mengel, M. Haas, R. B. Colvin, P. F. Halloran, L. C. Racusen, K. Solez, W. M. Baldwin, E. R. Bracamonte, V. Broecker, F. Cosio, A. J. Demetris, C. Drachenberg, G. Einecke, J. Gloor, D. Glotz, E. Kraus, C. Legendre, H. Liapis, R. B. MannonB. J. Nankivell, V. Nickeleit, J. C. Papadimitriou, P. Randhawa, H. Regele, K. Renaudin, E. R. Rodriguez, D. Seron, S. Seshan, Manikkam Suthanthiran, B. A. Wasowska, A. Zachary, A. Zeevi

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565 Citations (Scopus)

Abstract

The 10th Banff Conference on Allograft Pathology was held in Banff, Canada from August 9 to 14, 2009. A total of 263 transplant clinicians, pathologists, surgeons, immunologists and researchers discussed several aspects of solid organ transplants with a special focus on antibody mediated graft injury. The willingness of the Banff process to adapt continuously in response to new research and improve potential weaknesses, led to the implementation of six working groups on the following areas: isolated v-lesion, fibrosis scoring, glomerular lesions, molecular pathology, polyomavirus nephropathy and quality assurance. Banff working groups will conduct multicenter trials to evaluate the clinical relevance, practical feasibility and reproducibility of potential changes to the Banff classification. There were also sessions on quality improvement in biopsy reading and utilization of virtual microscopy for maintaining competence in transplant biopsy interpretation. In addition, compelling molecular research data led to the discussion of incorporation of omics-technologies and discovery of new tissue markers with the goal of combining histopathology and molecular parameters within the Banff working classification in the near future.

Original languageEnglish
Pages (from-to)464-471
Number of pages8
JournalAmerican Journal of Transplantation
Volume10
Issue number3
DOIs
Publication statusPublished - 1 Jan 2010
Externally publishedYes

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Keywords

  • Acute allograft rejection
  • Acute cellular rejection
  • Acute rejection
  • Allograft rejection
  • Antibody mediated rejection
  • Banff
  • Banff lesions
  • Banff schema
  • Chronic allograft rejection
  • Classification
  • Donor specific antibody
  • GeneChip
  • Genomic markers

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

Cite this

Sis, B., Mengel, M., Haas, M., Colvin, R. B., Halloran, P. F., Racusen, L. C., Solez, K., Baldwin, W. M., Bracamonte, E. R., Broecker, V., Cosio, F., Demetris, A. J., Drachenberg, C., Einecke, G., Gloor, J., Glotz, D., Kraus, E., Legendre, C., Liapis, H., ... Zeevi, A. (2010). Banff '09 meeting report: Antibody mediated graft deterioration and implementation of Banff working groups. American Journal of Transplantation, 10(3), 464-471. https://doi.org/10.1111/j.1600-6143.2009.02987.x