Bacterial drug delivery systems and nanoparticles

R. Sharma, Yousef Haik

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Drug delivery systems use different carrier cage-like structures such as bucky ball, therapeutic spheres, carbon nanotube spheres, tiny-tots, smart dots, paramagnetic nanoparticle cages, dendrimers, liposomes etc. The major developments are reported based on the physical properties of these particles such as paramagnetic, immunity, protein profile, transport dynamics, molecular recognition, receptor compatibility. In this approach drugs can be delivered efficiently at target and tracked in time-dependent manner for drug action at target with serial tissue changes by drug action. Several potential nanoparticles such as iron, zinc, cadmium, silver, gold, rhenium, gadolinium, lanthenum etc. have emerged as bioimaging contrast agents for MRI, radiography, optical, PET, SPECT imaging modalities. In principle, pH dependent delivery systems are designed based on the nanoparticle bound carrier as chemically visible complex by enzyme, chemiluminisence, antigenantibody, fluorescence, dye ratiometric reactions. Major developments are made in therapeutics in tumor, neuropathies, uropathies, cardiovascular diseases, blood and pancreas targeted therapies.

Original languageEnglish
Title of host publicationTechnical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
Pages61-64
Number of pages4
Volume2
Publication statusPublished - 2008
Externally publishedYes
Event2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008 - Quebec City, QC, United States
Duration: 1 Jun 20085 Jun 2008

Other

Other2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008
CountryUnited States
CityQuebec City, QC
Period1/6/085/6/08

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Keywords

  • Bioimaging
  • Drug delivery
  • Nanoparticles
  • Therapeutics

ASJC Scopus subject areas

  • Mechanical Engineering

Cite this

Sharma, R., & Haik, Y. (2008). Bacterial drug delivery systems and nanoparticles. In Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008 (Vol. 2, pp. 61-64)