Automated brachytherapy seed localization using intensity-weighted feature extraction techniques

Gregory Whitehead, Chang Zheng, Ji Jim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Brachytherapy has proven to be an effective treatment of various forms of cancer, whereby radioactive material is inserted directly into the body to maximize dosage to malignant tumors while preserving healthy tissue. In order to validate the pre-operative dosimetric model, a post-implant evaluation procedure is needed to ensure that the locations of the implanted seeds are consistent with the planning stage. Physicians require an automated algorithm for seed localization to expedite the post-implant evaluation process and reduce human error. Previously developed algorithms have performed binary transforms on images before attempting to localize seeds. Furthermore, traditional approaches based upon three-dimensional seed shape parameterization and matching require high resolution imaging. We propose a new algorithm for automatic seed localization for full three-dimensional data sets that utilizes voxel intensity for both seed centroid computation and estimation of angular seed orientation that is expected to produce reliable results even for low-resolution images.

Original languageEnglish
Title of host publication2007 4th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro - Proceedings
Pages1152-1155
Number of pages4
DOIs
Publication statusPublished - 27 Nov 2007
Event2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07 - Arlington, VA, United States
Duration: 12 Apr 200715 Apr 2007

Publication series

Name2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings

Other

Other2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07
CountryUnited States
CityArlington, VA
Period12/4/0715/4/07

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ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Medicine(all)

Cite this

Whitehead, G., Zheng, C., & Jim, J. (2007). Automated brachytherapy seed localization using intensity-weighted feature extraction techniques. In 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings (pp. 1152-1155). [4193495] (2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings). https://doi.org/10.1109/ISBI.2007.357061