Assessment of hyperparathyroidism

Judit Konya, Mo Aye, R. James England, Stephen Atkin

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Parathyroid hormone (PTH) in concert with 1,25-dihydroxyvitamin D regulates the level of calcium and phosphate from skeletal, renal, and intestinal actions. Hyperparathyroidism (HPT) is a common endocrinological disease characterized by an elevated parathyroid hormone (PTH). Hyperparathyroidism can be primary (autonomous hyperfunction of one or more parathyroid glands), secondary (physiological response to hypocalcemia due to an underlying disease), or tertiary (post renal transplantation).Primary HPT may be minimally symptomatic and coincidentally found. However, the signs and symptoms of hypercalcemia include renal, neurocognitive, musculoskeletal, gastrointestinal, and cardiovascular manifestations. Differential diagnoses that should be considered include vitamin D deficiency, malignancy, familial hypocalciuric hypercalcemia, and lithium or thiazide therapy.The definitive treatment of primary HPT is parathyroidectomy; however, the clinical and biochemical features may suggest that observation alone is optimal for the patient.

Original languageEnglish
Title of host publicationTips and Tricks in Endocrine Surgery
PublisherSpringer-Verlag London Ltd
Pages235-243
Number of pages9
ISBN (Electronic)9781447121466
ISBN (Print)9780857299826
DOIs
Publication statusPublished - 1 Jan 2014
Externally publishedYes

Fingerprint

Primary Hyperparathyroidism
Hyperparathyroidism
Parathyroid Hormone
Thiazides
Kidney
Parathyroidectomy
Parathyroid Glands
Vitamin D Deficiency
Hypocalcemia
Hypercalcemia
Lithium
Kidney Transplantation
Signs and Symptoms
Differential Diagnosis
Observation
Therapeutics
Neoplasms
calcium phosphate
Hypocalciuric hypercalcemia, familial, type 1
1,25-dihydroxyvitamin D

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Konya, J., Aye, M., England, R. J., & Atkin, S. (2014). Assessment of hyperparathyroidism. In Tips and Tricks in Endocrine Surgery (pp. 235-243). Springer-Verlag London Ltd. https://doi.org/10.1007/978-1-4471-2146-6_31

Assessment of hyperparathyroidism. / Konya, Judit; Aye, Mo; England, R. James; Atkin, Stephen.

Tips and Tricks in Endocrine Surgery. Springer-Verlag London Ltd, 2014. p. 235-243.

Research output: Chapter in Book/Report/Conference proceedingChapter

Konya, J, Aye, M, England, RJ & Atkin, S 2014, Assessment of hyperparathyroidism. in Tips and Tricks in Endocrine Surgery. Springer-Verlag London Ltd, pp. 235-243. https://doi.org/10.1007/978-1-4471-2146-6_31
Konya J, Aye M, England RJ, Atkin S. Assessment of hyperparathyroidism. In Tips and Tricks in Endocrine Surgery. Springer-Verlag London Ltd. 2014. p. 235-243 https://doi.org/10.1007/978-1-4471-2146-6_31
Konya, Judit ; Aye, Mo ; England, R. James ; Atkin, Stephen. / Assessment of hyperparathyroidism. Tips and Tricks in Endocrine Surgery. Springer-Verlag London Ltd, 2014. pp. 235-243
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