Abdominal aortic aneurysms and autosomal dominant polycystic kidney disease

Roser Torra, Carlos Nicolau, Cèlia Badenas, Concepció Brú, Laureano Pérez, Xavier P. Estivill, Alejandro Darnell

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Although cases of autosomal dominant polycystic kidney disease (ADPKD) associated with abdominal aortic aneurysm have been repeatedly reported in the literature, no systematic studies of the aortas of these patients have been performed. In the study presented here, a sonographic study of the abdominal aorta in 139 ADPKD patients and in 149 healthy family members was carded out. For both groups, an increase in aortic diameter related to age and sex, (being wider in men than women) was found. In ADPKD patients, neither a wider aortic diameter nor a higher prevalence of abdominal aortic aneurysms could be found in any age group. It was concluded that, although these patients are prone to develop aortic aneurysms because of hypertension and associated connective tissue disorders, the presence of abdominal aortic aneurysms should be questioned as o frequent feature of ADPKD.

Original languageEnglish
Pages (from-to)2483-2486
Number of pages4
JournalJournal of the American Society of Nephrology
Volume7
Issue number11
Publication statusPublished - Nov 1996
Externally publishedYes

    Fingerprint

Keywords

  • ADPKD
  • Aneurysm
  • Aorta
  • Diameter
  • Vascular

ASJC Scopus subject areas

  • Nephrology

Cite this

Torra, R., Nicolau, C., Badenas, C., Brú, C., Pérez, L., Estivill, X. P., & Darnell, A. (1996). Abdominal aortic aneurysms and autosomal dominant polycystic kidney disease. Journal of the American Society of Nephrology, 7(11), 2483-2486.