A new multiscale model for the mechanical behavior of vein walls

Mathieu Nierenberger, Yves Rémond, Saïd Ahzi

Research output: Contribution to journalArticle

9 Citations (Scopus)


The purpose of the present work is to propose a new multiscale model for the prediction of the mechanical behavior of vein walls. This model is based on one of our previous works which considered scale transitions applied to undulated collagen fibers. In the present work, the scale below was added to take the anisotropy of collagen fibrils into account. One scale above was also added, modeling the global reorientation of collagen fibers inside the vessel wall. The model was verified on experimental data from the literature, leading to a satisfactory agreement. The proposed multiscale approach also allows the extraction of local stresses and strains at each scale. This approach is presented here in the case of vein walls, but can easily be extended to other tissues which contain similar constituents.

Original languageEnglish
Pages (from-to)32-43
Number of pages12
JournalJournal of the Mechanical Behavior of Biomedical Materials
Publication statusPublished - 1 Jul 2013



  • Collagen fibers
  • Homogenization
  • Hyperelastic
  • Mechanical behavior
  • Mori-Tanaka
  • Multiscale
  • Vein walls

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Mechanics of Materials

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