A genetic inference on cancer immune responsiveness

Ena Wang, Lorenzo Uccellini, Francesco M. Marincola

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

A cancer immune signature implicating good prognosis and responsiveness to immunotherapy was described that is observed also in other aspects of immune-mediated, tissue-specific destruction (TSD). Its determinism remains, however, elusive. Based on limited but unique clinical observations, we propose a multifactorial genetic model of human cancer immune responsiveness.

Original languageEnglish
Pages (from-to)520-525
Number of pages6
JournalOncoImmunology
Volume1
Issue number4
DOIs
Publication statusPublished - 2 Nov 2012

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Keywords

  • Cancer genetics
  • Cancer microenvironment
  • Immune responsiveness
  • Immunotherapy
  • Melanoma

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Oncology

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