α1-Antitrypsin deficiency

Pathogenesis and treatment

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Inherited defects of the gene coding for a serum protein that protects alveolar walls from proteolysis constitute one cause of emphysema, with or without liver disease. The deficiency can be reversed with intravenous administration of the antiprotease, keeping serum levels above the minimum needed for lung protection.

Original languageEnglish
Pages (from-to)81-94
Number of pages14
JournalHospital Practice
Volume26
Issue number2
Publication statusPublished - 1 Jan 1991
Externally publishedYes

Fingerprint

Emphysema
Protease Inhibitors
Intravenous Administration
Proteolysis
Liver Diseases
Blood Proteins
Lung
Serum
Genes
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

α1-Antitrypsin deficiency : Pathogenesis and treatment. / Crystal, Ronald.

In: Hospital Practice, Vol. 26, No. 2, 01.01.1991, p. 81-94.

Research output: Contribution to journalArticle

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