• 5452 Citations
  • 15 h-Index
20042019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 5452 Citations
  • 15 h-Index
  • 22 Article
  • 1 Review article
Filter
Article
2019

Monoallelic expression in melanoma

Silcock, L., Almabrazi, H., Mokrab, Y., Jithesh, P., Al-Hashmi, M., James, N., Mathew, R., Mattei, V., Bedognetti, D., Lessi, F., Temanni, R., Seliger, B., Al-Ali, R., Marincola, F. M., Wang, E. & Tomei, S., 5 Apr 2019, In : Journal of translational medicine. 17, 1, 112.

Research output: Contribution to journalArticle

Open Access
2017

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Psychosis Endophenotypes International Consortium & CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium, 1 Jan 2017, In : Nature Genetics. 49, 1, p. 27-35 9 p.

Research output: Contribution to journalArticle

260 Citations (Scopus)

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

McLaughlin, R. L., Schijven, D., Van Rheenen, W., Van Eijk, K. R., O'Brien, M., Kahn, R. S., Ophoff, R. A., Goris, A., Bradley, D. G., Al-Chalabi, A., Van Den Berg, L. H., Luykx, J. J., Hardiman, O., Veldink, J. H., Shatunov, A., Dekker, A. M., Diekstra, F. P., Pulit, S. L., Van Der Spek, R. A. A., Van Doormaal, P. T. C. & 416 others, Sproviero, W., Jones, A. R., Nicholson, G. A., Rowe, D. B., Pamphlett, R., Kiernan, M. C., Bauer, D., Kahlke, T., Williams, K., Eftimov, F., Fogh, I., Ticozzi, N., Lin, K., Millecamps, S., Salachas, F., Meininger, V., Carvalho, M. D., Pinto, S., Mora, J. S., Rojas-Garcyá, R., Polak, M., Chandran, S., Colville, S., Swingler, R., Morrison, K. E., Shaw, P. J., Hardy, J., Orrell, R. W., Pittman, A., Sidle, K., Fratta, P., Malaspina, A., Petri, S., Abdulla, S., Drepper, C., Sendtner, M., Meyer, T., Wiedau-Pazos, M., Lomen-Hoerth, C., Deerlin, V. M. V., Trojanowski, J. Q., Elman, L., McCluskey, L., Basak, N., Meitinger, T., Lichtner, P., Blagojevic-Radivojkov, M., Andres, C. R., Maurel, C., Bensimon, G., Landwehrmeyer, B., Brice, A., Payan, C. A. M., Saker-Delye, S., Durr, A., Wood, N., Tittmann, L., Lieb, W., Franke, A., Rietschel, M., Cichon, S., Nothen, M. M., Amouyel, P., Tzourio, C., Dartigues, J. F., Uitterlinden, A. G., Rivadeneira, F., Estrada, K., Hofman, A., Curtis, C., Derkooi, A. J. V., De Visser, M., Weber, M., Shaw, C. E., Smith, B. N., Pansarasa, O., Cereda, C., Bo, R. D., Comi, G. P., D'Alfonso, S., Bertolin, C., Soraru, G., Mazzini, L., Pensato, V., Gellera, C., Tiloca, C., Ratti, A., Calvo, A., Moglia, C., Brunetti, M., Arcuti, S., Capozzo, R., Zecca, C., Lunetta, C., Penco, S., Riva, N., Padovani, A., Filosto, M., Blair, I., Nigel Leigh, P., Casale, F., Chio, A., Beghi, E., Pupillo, E., Tortelli, R., Logroscino, G., Powell, J., Ludolph, A. C., Weishaupt, J. H., Robberecht, W., Damme, P. V., Brown, R. H., Glass, J., Landers, J. E., Andersen, P. M., Corcia, P., Vourc'H, P., Silani, V., Es, M. A. V., Pasterkamp, R. J., Lewis, C. M., Breen, G., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chan, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Degenhardt, F., Favero, J. D., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Frank, J., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Genovese, G., Georgieva, L., Giegling, I., Giusti-Rodrýguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Gratten, J., De Haan, L., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, T., Haroutunian, V., Hartmann, A. M., Henskens, F. A., Herms, S., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Julia, A., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Keller, M. C., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kahler, A. K., Laurent, C., Lee, J., Hong Lee, S., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K. Y., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lonnqvist, J., MacEk, M., Magnusson, P. K. E., Maher, B. S., Maier, W., Mallet, J., Marsal, S., Mattheisen, M., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Muller-Myhsok, B., Nelis, M., Nenadic, I., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'Callaghan, E., O'Dushlaine, C., Anthony O'Neill, F., Oh, S. Y., Olincy, A., Olsen, L., Vanos, J., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietilainen, O., Pimm, J., Pocklington, A. J., Price, A., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, H. B., Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Ruderfer, D. M., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schulze, T. G., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stah, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Strohmaier, J., Scott Stroup, T., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Williams, S., Witt, S. H., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Wray, N. R., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gil, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jonsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarrol, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Riley, B. P., Rujescu, D., Sham, P. C., Sklar, P., Clair, D. S., Weinberger, D. R., Wendland, J. R., Werge, T., Daly, M. J., Sullivan, P. F. & O'Donovan, M. C., 21 Mar 2017, In : Nature communications. 8, 14774.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis

Hendrickx, W. R., Simeone, I., Anjum, S., Mokrab, Y., Bertucci, F., Finetti, P., Curigliano, G., Seliger, B., Cerulo, L., Tomei, S., Delogu, L. G., Maccalli, C., Wang, E., Miller, L. D., Marincola, F. M., Ceccarelli, M. & Bedognetti, D., 1 Feb 2017, In : OncoImmunology. 6, 2, e1253654.

Research output: Contribution to journalArticle

49 Citations (Scopus)
2016

Advances in the genetics of schizophrenia: Toward a network and pathway view for drug discovery

Collier, D. A., Eastwood, B. J., Malki, K. & Mokrab, Y., 1 Feb 2016, In : Annals of the New York Academy of Sciences. 1366, 1, p. 61-75 15 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Gene-set analysis based on the pharmacological profiles of drugs to identify repurposing opportunities in schizophrenia

De Jong, S., Vidler, L. R., Mokrab, Y., Collier, D. A. & Breen, G., 1 Aug 2016, In : Journal of Psychopharmacology. 30, 8, p. 826-830 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Oct 2016, In : PLoS genetics. 12, 10, e1006343.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Proton currents constrain structural models of voltage sensor activation

Randolph, A. L., Mokrab, Y., Bennett, A. L., Sansom, M. S. P. & Ramsey, I. S., 30 Aug 2016, In : eLife. 5, AUGUST, e18017.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2015

LD score regression distinguishes confounding from polygenicity in genome-wide association studies

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 25 Feb 2015, In : Nature Genetics. 47, 3, p. 291-295 5 p.

Research output: Contribution to journalArticle

863 Citations (Scopus)

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Psychosis Endophenotypes International Consortium, Wellcome Trust Case Control Consortium, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study & Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON), 1 Jan 2015, In : American Journal of Human Genetics. 97, 4, p. 576-592 17 p.

Research output: Contribution to journalArticle

215 Citations (Scopus)
2014

Biological insights from 108 schizophrenia-associated genetic loci

Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J. & 280 others, Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Degenhardt, F., Del Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Frank, J., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Genovese, G., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Gratten, J., De Haan, L., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, T., Haroutunian, V., Hartmann, A. M., Henskens, F. A., Herms, S., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Julià, A., Kahn, R. S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Keller, M. C., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kähler, A. K., Laurent, C., Keong, J. L. C., Lee, S. H., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K. Y., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lönnqvist, J., Macek, M., Magnusson, P. K. E., Maher, B. S., Maier, W., Mallet, J., Marsal, S., Mattheisen, M., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Müller-Myhsok, B., Nelis, M., Nenadic, I., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'Callaghan, E., O'Dushlaine, C., O'Neill, F. A., Oh, S. Y., Olincy, A., Olsen, L., Van Os, J., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietiläinen, O., Pimm, J., Pocklington, A. J., Powell, J., Price, A., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, H. B., Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Ruderfer, D. M., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schulze, T. G., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stahl, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Strohmaier, J., Stroup, T. S., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Williams, S., Witt, S. H., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Wray, N. R., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Cichon, S., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gill, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jönsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarroll, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Nöthen, M. M., Ophoff, R. A., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Rietschel, M., Riley, B. P., Rujescu, D., Sham, P. C., Sklar, P., St Clair, D., Weinberger, D. R., Wendland, J. R., Werge, T., Daly, M. J., Sullivan, P. F. & O'Donovan, M. C., 1 Jan 2014, In : Nature. 511, 7510, p. 421-427 7 p.

Research output: Contribution to journalArticle

3297 Citations (Scopus)

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

Wellcome Trust Case Control Consortium, SWE-SCZ Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, SWE-SCZ Consortium & Psychosis Endophenotypes International Consortium, 1 Jan 2014, In : American Journal of Human Genetics. 95, 5, p. 535-552 18 p.

Research output: Contribution to journalArticle

260 Citations (Scopus)
2011

Identification of novel functional organic anion-transporting polypeptide 1B3 polymorphisms and assessment of substrate specificity

Schwarz, U. I., Schwabedissen, H. E. M. Z., Tirona, R. G., Suzuki, A., Leake, B. F., Mokrab, Y., Mizuguchi, K., Ho, R. H. & Kim, R. B., 1 Mar 2011, In : Pharmacogenetics and Genomics. 21, 3, p. 103-114 12 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Interaction of diverse voltage sensor homologs with lipid bilayers revealed by self-assembly simulations

Mokrab, Y. & Sansom, M. S. P., 16 Feb 2011, In : Biophysical Journal. 100, 4, p. 875-884 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2010

An aqueous H + permeation pathway in the voltage-gated proton channel Hv1

Ramsey, I. S., Mokrab, Y., Carvacho, I., Sands, Z. A., Sansom, M. S. P. & Clapham, D. E., 1 Jul 2010, In : Nature Structural and Molecular Biology. 17, 7, p. 869-875 7 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)

A structural dissection of amino acid substitutions in helical transmembrane proteins

Mokrab, Y., Stevens, T. J. & Mizuguchi, K., 1 Nov 2010, In : Proteins: Structure, Function and Bioinformatics. 78, 14, p. 2895-2907 13 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2009

Lipophobicity and the residue environments of the transmembrane α-helical bundle

Mokrab, Y., Stevens, T. J. & Mizuguchi, K., 1 Jan 2009, In : Proteins: Structure, Function and Bioinformatics. 74, 1, p. 32-49 18 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2008

CGDB: A database of membrane protein/lipid interactions by coarse-grained molecular dynamics simulations

Chetwynd, A. P., Scott, K. A., Mokrab, Y. & Sansom, M. S. P., 1 Dec 2008, In : Molecular Membrane Biology. 25, 8, p. 662-669 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2007

Exploring ligand recognition and ion flow in comparative models of the human GABA type A receptor

Mokrab, Y., Bavro, V. N., Mizuguchi, K., Todorov, N. P., Martin, I. L., Dunn, S. M. J., Chan, S. L. & Chau, P. L., 1 Nov 2007, In : Journal of Molecular Graphics and Modelling. 26, 4, p. 760-774 15 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2006
94 Citations (Scopus)

The guanidino-group modifying enzymes: Structural basis for their diversity and commonality

Shirai, H., Mokrab, Y. & Mizuguchi, K., 1 Sep 2006, In : Proteins: Structure, Function and Genetics. 64, 4, p. 1010-1023 14 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2004

A genome annotation-driven approach to cloning the human ORFeome.

Collins, J. E., Wright, C. L., Edwards, C. A., Davis, M. P., Grinham, J. A., Cole, C. G., Goward, M. E., Aguado, B., Mallya, M., Mokrab, Y., Huckle, E. J., Beare, D. M. & Dunham, I., 2004, In : Genome biology. 5, 10, p. R84

Research output: Contribution to journalArticle

24 Citations (Scopus)