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Research Output 2005 2019

  • 673 Citations
  • 15 h-Index
  • 22 Article
  • 4 Review article
  • 2 Letter
  • 1 Comment/debate
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Article
2019

Transcriptomic profiles conducive to immune-mediated tumor rejection in human breast cancer skin metastases treated with Imiquimod

Rozenblit, M., Hendrickx, W. R., Heguy, A., Chiriboga, L., Loomis, C., Ray, K., Darvishian, F., Egeblad, M., Demaria, S., Marincola, F. M., Bedognetti, D. & Adams, S., 1 Dec 2019, In : Scientific reports. 9, 1, 8572.

Research output: Contribution to journalArticle

Open Access
imiquimod
Skin Neoplasms
Breast Neoplasms
Neoplasm Metastasis
Neoplasms
2018

A collection of annotated and harmonized human breast cancer transcriptome datasets, including immunologic classification

Miller, L. D., Roelands, J., Decock, J., Boughorbel, S., Rinchai, D., Maccalli, C., Ceccarelli, M., Black, M., Print, C., Chou, J., Presnell, S., Quinn, C., Jithesh, P. V., Syed, N., Al Bader, S. B. J., Bedri, S., Wang, E., Marincola, F. M., Chaussabel, D. J., Kuppen, P. & 2 others, Bedognetti, D. & Hendrickx, W. R., 1 Jan 2018, In : F1000Research. 6, 296.

Research output: Contribution to journalArticle

Transcriptome
Gene expression
Breast Neoplasms
Gene Expression
Genes
7 Citations (Scopus)

Immune oncology, immune responsiveness and the theory of everything

Turan, T., Kannan, D., Patel, M., Matthew Barnes, J., Tanlimco, S. G., Lu, R., Halliwill, K., Kongpachith, S., Kline, D. E., Hendrickx, W. R., Cesano, A., Butterfield, L. H., Kaufman, H. L., Hudson, T. J., Bedognetti, D., Marincola, F. & Samayoa, J., 5 Jun 2018, In : Journal for ImmunoTherapy of Cancer. 6, 1, 50.

Research output: Contribution to journalArticle

Neoplasms
Immunotherapy
Immune Evasion
Tumor Microenvironment
Advisory Committees
6 Citations (Scopus)

The immunologic constant of rejection classification refines the prognostic value of conventional prognostic signatures in breast cancer

Bertucci, F., Finetti, P., Simeone, I., Hendrickx, W. R., Wang, E., Marincola, F. M., Viens, P., Mamessier, E., Ceccarelli, M., Birnbaum, D. & Bedognetti, D., 1 Jan 2018, (Accepted/In press) In : British Journal of Cancer.

Research output: Contribution to journalArticle

Breast Neoplasms
Risk Reduction Behavior
Recurrence
Genes
Rejection (Psychology)
2017
42 Citations (Scopus)

Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis

Hendrickx, W. R., Simeone, I., Anjum, S., Mokrab, Y., Bertucci, F., Finetti, P., Curigliano, G., Seliger, B., Cerulo, L., Tomei, S., Delogu, L. G., Maccalli, C., Wang, E., Miller, L. D., Marincola, F. M., Ceccarelli, M. & Bedognetti, D., 1 Feb 2017, In : OncoImmunology. 6, 2, e1253654.

Research output: Contribution to journalArticle

Genome
Breast Neoplasms
Phenotype
Mutation
Atlases
22 Citations (Scopus)

Single-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells

Orecchioni, M., Bedognetti, D., Newman, L., Fuoco, C., Spada, F., Hendrickx, W. R., Marincola, F. M., Sgarrella, F., Rodrigues, A. F., Ménard-Moyon, C., Cesareni, G., Kostarelos, K., Bianco, A. & G Delogu, L., 1 Dec 2017, In : Nature Communications. 8, 1, 1109.

Research output: Contribution to journalArticle

cytometry
Graphite
Gene Expression Profiling
graphene
Oxides
16 Citations (Scopus)

Soluble NKG2D ligands are biomarkers associated with the clinical outcome to immune checkpoint blockade therapy of metastatic melanoma patients

Maccalli, C., Giannarelli, D., Chiarucci, C., Cutaia, O., Giacobini, G., Hendrickx, W. R., Amato, G., Annesi, D., Bedognetti, D., Altomonte, M., Danielli, R., Calabrò, L., Di Giacomo, A. M., Marincola, F. M., Parmiani, G. & Maio, M., 3 Jul 2017, In : OncoImmunology. 6, 7, e1323618.

Research output: Contribution to journalArticle

Melanoma
Biomarkers
Ligands
Therapeutics
Serum
2016
11 Citations (Scopus)

Disentangling the relationship between tumor genetic programs and immune responsiveness

Bedognetti, D., Hendrickx, W. R., Ceccarelli, M., Miller, L. D. & Seliger, B., 1 Apr 2016, In : Current Opinion in Immunology. 39, p. 150-158 9 p.

Research output: Contribution to journalArticle

Phenotype
Neoplasms
Chemokines
Genes
Cytokines
30 Citations (Scopus)

Immunogenic subtypes of breast cancer delineated by gene classifiers of immune responsiveness

Miller, L. D., Chou, J. A., Black, M. A., Print, C., Chifman, J., Alistar, A., Putti, T., Zhou, X., Bedognetti, D., Hendrickx, W. R., Pullikuth, A., Rennhack, J., Andrechek, E. R., Demaria, S., Wang, E. & Marincola, F. M., 1 Jul 2016, In : Cancer immunology research. 4, 7, p. 600-610 11 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Breast Neoplasms
Neoplasms
Neoplasm Metastasis
Activation Analysis
2015
14 Citations (Scopus)

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice

Decock, J., Hendrickx, W. R., Thirkettle, S., Gutiérrez-Fernández, A., Robinson, S. D. & Edwards, D. R., 2015, In : Breast Cancer Research. 17, p. 38 1 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 8
Transgenic Mice
Breast Neoplasms
Neoplasm Metastasis
Matrix Metalloproteinases
2013
7 Citations (Scopus)

Selenium biomarkers in prostate cancer cell lines and influence of selenium on invasive potential of PC3 cells

Hendrickx, W. R., Decock, J., Mulholland, F., Bao, Y. & Fairweather-Tait, S., 31 Dec 2013, In : Frontiers in Oncology. 3 SEP, Article 239.

Research output: Contribution to journalArticle

Selenium
Prostatic Neoplasms
Biomarkers
Cell Line
Thioredoxin Reductase 1
2009
64 Citations (Scopus)

Axillary lymph node status of operable breast cancers by combined steroid receptor and HER-2 status: Triple positive tumours are more likely lymph node positive

Van Calster, B., Vanden Bempt, I., Drijkoningen, M., Pochet, N., Cheng, J., Van Huffel, S., Hendrickx, W. R., Decock, J., Huang, H. J., Leunen, K., Amant, F., Berteloot, P., Paridaens, R., Wildiers, H., Van Limbergen, E., Weltens, C., Timmerman, D., Van Gorp, T., Smeets, A., Van Den Bogaert, W. & 3 others, Vergote, I., Christiaens, M. R. & Neven, P., 1 Jan 2009, In : Breast Cancer Research and Treatment. 113, 1, p. 181-187 7 p.

Research output: Contribution to journalArticle

Steroid Receptors
Progesterone Receptors
Lymph Nodes
Breast Neoplasms
Neoplasms
49 Citations (Scopus)

Relationship between age and axillary lymph node involvement in women with breast cancer

Wildiers, H., Van Calster, B., Van De Poll-Franse, L. V., Hendrickx, W. R., Røislien, J., Smeets, A., Paridaens, R., Deraedt, K., Leunen, K., Weltens, C., Van Huffel, S., Christiaens, M. R. & Neven, P., 20 Jun 2009, In : Journal of Clinical Oncology. 27, 18, p. 2931-2937 7 p.

Research output: Contribution to journalArticle

Lymph Nodes
Breast Neoplasms
Databases
Neoplasms
Registries
19 Citations (Scopus)

Short-term outcome of primary operated early breast cancer by hormone and HER-2 receptors

Brouckaert, O., Pintens, S., Van Belle, V., Van Huffel, S., Camerlynck, E., Amant, F., Leunen, K., Smeets, A., Berteloot, P., Van Limbergen, E., Decock, J., Hendrickx, W. R., Weltens, C., Van Den Bogaert, W., Vanden Bempt, I., Drijkoningen, M., Paridaens, R., Wildiers, H., Vergote, I., Christiaens, M. R. & 1 others, Neven, P., 1 May 2009, In : Breast Cancer Research and Treatment. 115, 2, p. 349-358 10 p.

Research output: Contribution to journalArticle

Hormones
Breast Neoplasms
Staining and Labeling
Steroid Receptors
Neoplasm Genes
2008
11 Citations (Scopus)

Age interacts with the expression of steroid and HER-2 receptors in operable invasive breast cancer

Neven, P., Van Calster, B., Van Den Bempt, I., Van Huffel, S., Van Belle, V., Hendrickx, W. R., Decock, J., Wildiers, H., Paridaens, R., Amant, F., Leunen, K., Berteloot, P., Timmerman, D., Van Limbergen, E., Weltens, C., Van Den Bogaert, W., Smeets, A., Vergote, I., Christiaens, M. R. & Drijkoningen, M., 1 Jul 2008, In : Breast Cancer Research and Treatment. 110, 1, p. 153-159 7 p.

Research output: Contribution to journalArticle

Steroids
Breast Neoplasms
Progesterone Receptors
Steroid Receptors
Odds Ratio
44 Citations (Scopus)

Cathepsin B, cathepsin H, cathepsin X and cystatin C in sera of patients with early-stage and inflammatory breast cancer

Decock, J., Obermajer, N., Vozelj, S., Hendrickx, W. R., Paridaens, R. & Kos, J., 1 Dec 2008, In : International Journal of Biological Markers. 23, 3, p. 161-168 8 p.

Research output: Contribution to journalArticle

Cathepsin H
Cathepsin C
Inflammatory Breast Neoplasms
Cystatin C
Cathepsins
10 Citations (Scopus)

Clinicopathological features of inflammatory versus noninflammatory locally advanced nonmetastatic breast cancer

Brouwers, B., Paridaens, R., Lobelle, J. P., Hendrickx, W. R., Smeets, A., Neven, P., Weltens, C., Deraedt, K., Vanden Bempt, I., Christiaens, M. R. & Wildiers, H., 1 Sep 2008, In : Tumor Biology. 29, 4, p. 211-216 6 p.

Research output: Contribution to journalArticle

Inflammatory Breast Neoplasms
Breast Neoplasms
Progesterone Receptors
Estrogen Receptors
Body Mass Index
54 Citations (Scopus)

Plasma MMP1 and MMP8 expression in breast cancer: Protective role of MMP8 against lymph node metastasis

Decock, J., Hendrickx, W. R., Vanleeuw, U., Van Belle, V., Van Huffel, S., Christiaens, M. R., Ye, S. & Paridaens, R., 20 Mar 2008, In : BMC Cancer. 8, 77.

Research output: Contribution to journalArticle

Lymph Nodes
Breast Neoplasms
Neoplasm Metastasis
Inflammatory Breast Neoplasms
Cytoprotection
2007
68 Citations (Scopus)

Association of matrix metalloproteinase-8 gene variation with breast cancer prognosis

Decock, J., Long, J. R., Laxton, R. C., Shu, X. O., Hodgkinson, C., Hendrickx, W. R., Pearce, E. G., Gao, Y. T., Pereira, A. C., Paridaens, R., Zheng, W. & Ye, S., 1 Nov 2007, In : Cancer Research. 67, 21, p. 10214-10221 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 8
Alleles
Breast Neoplasms
Single Nucleotide Polymorphism
Neoplasm Metastasis
12 Citations (Scopus)

Body mass index and HER-2 overexpression in breast cancer patients over 50 years of age

Van Mieghem, T., Leunen, K., Pochet, N., De Moor, B., De Smet, F., Amant, F., Berteloot, P., Timmerman, D., Vanden Bempt, I., Drijkoningen, R., Wildiers, H., Paridaens, R., Smeets, A., Hendrickx, W. R., Van Limbergen, E., Christiaens, M. R., Vergote, I. & Neven, P., 1 Nov 2007, In : Breast Cancer Research and Treatment. 106, 1, p. 127-133 7 p.

Research output: Contribution to journalArticle

Body Mass Index
Breast Neoplasms
Steroid Receptors
Estrogens
Logistic Models
19 Citations (Scopus)

Matrix metalloproteinase expression patterns in luminal A type breast carcinomas

Decock, J., Hendrickx, W. R., Drijkoningen, M., Wildiers, H., Neven, P., Smeets, A. & Paridaens, R., 11 Jun 2007, In : Disease Markers. 23, 3, p. 189-196 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Breast Neoplasms
Ductal Carcinoma
RNA
Tumors
2005
18 Citations (Scopus)

Plasma gelatinase levels in patients with primary breast cancer in relation to axillary lymph node status, Her2/neu expression and other clinicopathological variables

Decock, J., Hendrickx, W. R., Wildiers, H., Christiaens, M. R., Neven, P., Drijkoningen, M. & Paridaens, R., 1 Nov 2005, In : Clinical and Experimental Metastasis. 22, 6, p. 495-502 8 p.

Research output: Contribution to journalArticle

Gelatinases
Lymph Nodes
Breast Neoplasms
Neoplasms
Neoplasm Metastasis