• 288 Citations
  • 8 h-Index
20092019
If you made any changes in Pure these will be visible here soon.

Research Output 2009 2019

  • 288 Citations
  • 8 h-Index
  • 9 Article
  • 1 Chapter
  • 1 Review article
2019

IKKβ targeting reduces KRAS-induced lung cancer angiogenesis in vitro and in vivo: A potential anti-angiogenic therapeutic target

Lobo, T., Scalabrini, L. C., Magalhães, L. D. S., Cardeal, L. B., Rodrigues, F. S., dos Santos, E. O., Baldwin, A. S., Levantini, E., Giordano, R. J. & Bassères, D. S., 1 Apr 2019, In : Lung Cancer. 130, p. 169-178 10 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Neoplasms
Lung
Small Interfering RNA
Therapeutics
2016
16 Citations (Scopus)

Aurora kinase targeting in lung cancer reduces KRAS-induced transformation

dos Santos, E. O., Lobo, T., Aoki, M. N., Levantini, E. & Bassères, D. S., 3 Feb 2016, In : Molecular Cancer. 15, 1, 12.

Research output: Contribution to journalArticle

Aurora Kinases
Aurora Kinase A
Lung Neoplasms
Small Interfering RNA
Phosphotransferases
12 Citations (Scopus)

Hypoxia regulates the expression of tissue factor pathway signaling elements in a rat glioma model

Monteiro, R. Q., Lima, L. G., Gon�alves, N. P., de Souza, M. R. A., Leal, A. C., Demasi, M. A. A., Sogayar, M. C. & Lobo, T., 1 Jul 2016, In : Oncology Letters. 12, 1, p. 315-322 8 p.

Research output: Contribution to journalArticle

Thromboplastin
Glioma
Neoplasms
Hypoxia
Necrosis
2015

Ecotin: Exploring a feasible antithrombotic profile

Wermelinger, L. S., Frattani, F. S., Lobo, T., Craik, C. S., Castro, H. C. & Zingali, R. B., 1 Jul 2015, In : International Journal of Biological Macromolecules. 78, p. 296-303 8 p.

Research output: Contribution to journalArticle

Thrombosis
Pulmonary Embolism
Proteins
Bleeding Time
Escherichia coli Proteins
2014
20 Citations (Scopus)

Expression of tissue factor signaling pathway elements correlates with the production of vascular endothelial growth factor and interleukin-8 in human astrocytoma patients

Lobo, T., Lima, M. T., Mariano-Oliveira, A., Dutra-Oliveira, A., Oba-Shinjo, S. M., Marie, S. K. N., Sogayar, M. C. & Monteiro, R. Q., 1 Feb 2014, In : Oncology Reports. 31, 2, p. 679-686 8 p.

Research output: Contribution to journalArticle

Astrocytoma
Thromboplastin
Interleukin-8
Vascular Endothelial Growth Factor A
Proteinase-Activated Receptors
2013
39 Citations (Scopus)

Endothelial Protein C Receptor Function in Murine and Human Breast Cancer Development

Schaffner, F., Yokota, N., Lobo, T., Kitano, M., Schaffer, M., Anderson, G. M., Mueller, B. M., Esmon, C. T. & Ruf, W., 9 Apr 2013, In : PLoS One. 8, 4, e61071.

Research output: Contribution to journalArticle

Protein C
breast neoplasms
Tumors
Breast Neoplasms
Neoplastic Stem Cells
2012

Anticoagulants as a therapeutic alternative for glioblastoma treatment

Lobo, T., Konig, S. & Monteiro, R. Q., 1 Jan 2012, Glioblastoma: Risk Factors, Diagnosis and Treatment Options. Nova Science Publishers, Inc., p. 201-226 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Glioblastoma
Anticoagulants
Tumors
Thromboplastin
Coagulation
26 Citations (Scopus)

The tick-derived inhibitor Ixolaris prevents tissue factor signaling on tumor cells

Lobo, T., Schaffner, F., Disse, J., Ostergaard, H., Francischetti, I. M. B., Monteiro, R. Q. & Ruf, W., 1 Sep 2012, In : Journal of Thrombosis and Haemostasis. 10, 9, p. 1849-1858 10 p.

Research output: Contribution to journalArticle

Thromboplastin
Ticks
Neoplasms
Breast Neoplasms
Factor VIIa
2011
16 Citations (Scopus)

Increased expression of protease-activated receptor 1 (PAR-1) in human leukemias

Veiga, C. D. S. B., Lobo, T., Coelho, C. J. B. P., Carvalho, S. M. F., Maia, R. C., Vasconcelos, F. C., Abdelhay, E., Mencalha, A. L., Ferreira, A. F., Castro, F. A. & Monteiro, R. Q., 15 Mar 2011, In : Blood Cells, Molecules, and Diseases. 46, 3, p. 230-234 5 p.

Research output: Contribution to journalArticle

PAR-1 Receptor
Leukemia
Tissue Donors
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Precursor Cell Lymphoblastic Leukemia-Lymphoma
101 Citations (Scopus)

Tissue factor and cell signalling in cancer progression and thrombosis

Ruf, W., Disse, J., Lobo, T., Yokota, N. & Schaffner, F., 1 Jul 2011, In : Journal of Thrombosis and Haemostasis. 9, 1 S, p. 306-315 10 p.

Research output: Contribution to journalReview article

Thromboplastin
Thrombosis
Neoplasms
Proteinase-Activated Receptors
Peptide Hydrolases
2009
58 Citations (Scopus)

Ixolaris, a tissue factor inhibitor, blocks primary tumor growth and angiogenesis in a glioblastoma model

Lobo, T., Konig, S., Machado, D. E., Nasciutti, L. E., Forni, M. F., Francischetti, I. M. B., Sogayar, M. C. & Monteiro, R. Q., 1 Nov 2009, In : Journal of Thrombosis and Haemostasis. 7, 11, p. 1855-1864 10 p.

Research output: Contribution to journalArticle

Thromboplastin
Glioblastoma
cancer procoagulant
Growth
Neoplasms