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1980 …2016

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Article
2016

Chromatin associated mechanisms in base excision repair - nucleosome remodeling and DNA transcription, two key players

Menoni, H., Di Mascio, P., Cadet, J., Dimitrov, S. & Angelov, D., 27 Sep 2016, (Accepted/In press) In : Free Radical Biology and Medicine.

Research output: Contribution to journalArticle

13 Citations (Scopus)

FACT Assists Base Excision Repair by Boosting the Remodeling Activity of RSC

Charles Richard, J. L., Shukla, M. S., Menoni, H., Ouararhni, K., Lone, I. N., Roulland, Y., Papin, C., Ben Simon, E., Kundu, T., Hamiche, A., Angelov, D. & Dimitrov, S., Jul 2016, In : PLoS genetics. 12, 7, e1006221.

Research output: Contribution to journalArticle

14 Citations (Scopus)

H1-nucleosome interactions and their functional implications

Bednar, J., Hamiche, A. & Dimitrov, S., 1 Mar 2016, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1859, 3, p. 436-443 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Molecular basis and specificity of H2A.Z-H2B recognition and deposition by the histone chaperone YL1

Latrick, C. M., Marek, M., Ouararhni, K., Papin, C., Stoll, I., Ignatyeva, M., Obri, A., Ennifar, E., Dimitrov, S., Romier, C. & Hamiche, A., 5 Apr 2016, In : Nature Structural and Molecular Biology. 23, 4, p. 309-316 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity

Roulland, Y., Ouararhni, K., Naidenov, M., Ramos, L., Shuaib, M., Syed, S. H., Lone, I. N., Boopathi, R., Fontaine, E., Papai, G., Tachiwana, H., Gautier, T., Skoufias, D., Padmanabhan, K., Bednar, J., Kurumizaka, H., Schultz, P., Angelov, D., Hamiche, A. & Dimitrov, S., 18 Aug 2016, In : Molecular Cell. 63, 4, p. 674-685 12 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2014

ANP32E is a histone chaperone that removes H2A.Z from chromatin

Obri, A., Ouararhni, K., Papin, C., Diebold, M. L., Padmanabhan, K., Marek, M., Stoll, I., Roy, L., Reilly, P. T., Mak, T. W., Dimitrov, S., Romier, C. & Hamiche, A., 28 Jan 2014, In : Nature. 505, 7485, p. 648-653 6 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)

Centromeric histone variant CENP-A represses acetylation-dependent chromatin transcription that is relieved by histone chaperone NPM1

Shandilya, J., Senapati, P., Hans, F., Menoni, H., Bouvet, P., Dimitrov, S., Angelov, D. & Kundu, T. K., 1 Jan 2014, In : Journal of Biochemistry. 156, 4, p. 221-227 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2013

Binding of NF-κB to Nucleosomes: Effect of Translational Positioning, Nucleosome Remodeling and Linker Histone H1

Lone, I. N., Shukla, M. S., Charles Richard, J. L., Peshev, Z. Y., Dimitrov, S. & Angelov, D., 1 Sep 2013, In : PLoS genetics. 9, 9, e1003830.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Phosphorylation of the CENP-A amino-terminus in mitotic centromeric chromatin is required for kinetochore function

Goutte-Gattat, D., Shuaib, M., Ouararhni, K., Gautier, T., Skoufias, D. A., Hamiche, A. & Dimitrov, S., 21 May 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 21, p. 8579-8584 6 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2012

Base excision repair of 8-oxoG in dinucleosomes

Menoni, H., Shukla, M. S., Gerson, V., Dimitrov, S. & Angelov, D., 1 Jan 2012, In : Nucleic acids research. 40, 2, p. 692-700 9 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Direct cooperation between androgen receptor and E2F1 reveals a common regulation mechanism for androgen-responsive genes in prostate cells

Altintas, D. M., Shukla, M. S., Goutte-Gattat, D., Angelov, D., Rouault, J. P., Dimitrov, S. & Samarut, J., 1 Sep 2012, In : Molecular Endocrinology. 26, 9, p. 1531-1541 11 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2011

Cell cycle regulated expression of NCoR might control cyclic expression of androgen responsive genes in an immortalized prostate cell line

Altintas, D. M., Vlaeminck, V., Angelov, D., Dimitrov, S. & Samarut, J., 30 Jan 2011, In : Molecular and Cellular Endocrinology. 332, 1-2, p. 149-162 14 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits

Wong, D., Teixeira, A., Oikonomopoulos, S., Humburg, P., Lone, I. N., Saliba, D., Siggers, T., Bulyk, M., Angelov, D., Dimitrov, S., Udalova, I. A. & Ragoussis, J., 19 Jul 2011, In : Genome biology. 12, 7, r70.

Research output: Contribution to journalArticle

88 Citations (Scopus)

From crystal and NMR structures, footprints and cryo-electron-micrographs to large and soft structures: Nanoscale modeling of the nucleosomal stem

Meyer, S., Becker, N. B., Syed, S. H., Goutte-Gattat, D., Shukla, M. S., Hayes, J. J., Angelov, D., Bednar, J., Dimitrov, S. & Everaers, R., 1 Nov 2011, In : Nucleic acids research. 39, 21, p. 9139-9154 16 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Histone H3 trimethylation at lysine 36 is associated with constitutive and facultative heterochromatin

Chantalat, S., Depaux, A., Héry, P., Barral, S., Thuret, J. Y., Dimitrov, S. & Gérard, M., 1 Sep 2011, In : Genome Research. 21, 9, p. 1426-1437 12 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

RSC remodeling of oligo-nucleosomes: An atomic force microscopy study

Montel, F., Castelnovo, M., Menoni, H., Angelov, D., Dimitrov, S. & Faivre-Moskalenko, C., Apr 2011, In : Nucleic acids research. 39, 7, p. 2571-2579 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

The docking domain of histone H2A is required for H1 binding and RSC-mediated nucleosome remodeling

Shukla, M. S., Syed, S. H., Goutte-Gattat, D., Richard, J. L. C., Montel, F., Hamiche, A., Travers, A., Faivre-Moskalenko, C., Bednar, J., Hayes, J. J., Angelov, D. & Dimitrov, S., Apr 2011, In : Nucleic acids research. 39, 7, p. 2559-2570 12 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

The multifunctional protein nucleophosmin (NPM1) is a human linker histone H1 chaperone

Gadad, S. S., Senapati, P., Syed, S. H., Rajan, R. E., Shandilya, J., Swaminathan, V., Chatterjee, S., Colombo, E., Dimitrov, S., Pelicci, P. G., Ranga, U. & Kundu, T. K., 12 Apr 2011, In : Biochemistry. 50, 14, p. 2780-2789 10 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2010
125 Citations (Scopus)

Remosomes: RSC generated non-mobilized particles with approximately 180 bp DNA loosely associated with the histone octamer

Shukla, M. S., Syed, S. H., Montel, F., Faivre-Moskalenko, C., Bednar, J., Travers, A., Angelov, D. & Dimitrov, S., 2 Feb 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 5, p. 1936-1941 6 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Single-base resolution mapping of H1-nucleosome interactions and 3D organization of the nucleosome

Syed, S. H., Goutte-Gattat, D., Becker, N., Meyer, S., Shukla, M. S., Hayes, J. J., Everaers, R., Angelov, D., Bednar, J. & Dimitrov, S., 25 May 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 21, p. 9620-9625 6 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)
2009

Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases

Hoang, T. M. N., Favier, B., Valette, A., Barette, C., Chi, H. N., Lafanechère, L., Grierson, D. S., Dimitrov, S. & Molla, A., 1 Mar 2009, In : Cell Cycle. 8, 5, p. 765-772 8 p.

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Molecular distinctions between Aurora A and B: A single residue change transforms Aurora A into correctly localized and functional Aurora B

Hans, F., Skoufias, D. A., Dimitrov, S. & Margolis, R. L., 1 Aug 2009, In : Molecular Biology of the Cell. 20, 15, p. 3491-3502 12 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

The dynamics of individual nucleosomes controls the chromatin condensation pathway: Direct atomic force microscopy visualization of variant chromatin

Montel, F., Menoni, H., Castelnovo, M., Bednar, J., Dimitrov, S., Angelov, D. & Faivre-Moskalenko, C., 1 Jan 2009, In : Biophysical Journal. 97, 2, p. 544-553 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

The incorporation of the novel histone variant H2AL2 confers unusual structural and functional properties of the nucleosome

Syed, S. H., Boulard, M., Shukla, M. S., Gautier, T., Travers, A., Bednar, J., Faivre-Moskalenko, C., Dimitrov, S. & Angelov, D., 1 Jan 2009, In : Nucleic acids research. 37, 14, p. 4684-4695 12 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Weak but uniform enrichment of the histone variant macroH2A1 along the inactive X chromosome

Mietton, F., Sengupta, A. K., Molla, A., Picchi, G., Barral, S., Heliot, L., Grange, T., Wutz, A. & Dimitrov, S., 1 Jan 2009, In : Molecular and Cellular Biology. 29, 1, p. 150-156 7 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2008

Localization of aurora A and aurora B kinases during interphase: Role of the N-terminal domain

Rannou, Y., Troadec, M. B., Petretti, C., Hans, F., Dutertre, S., Dimitrov, S. & Prigent, C., 1 Oct 2008, In : Cell Cycle. 7, 19, p. 3012-3020 9 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)
2007

ATP-dependent chromatin remodeling is required for base excision repair in conventional but not in variant H2A.Bbd nucleosomes

Menoni, H., Gasparutto, D., Hamiche, A., Cadet, J., Dimitrov, S., Bouvet, P. & Angelov, D., Sep 2007, In : Molecular and Cellular Biology. 27, 17, p. 5949-5956 8 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Functions of the histone chaperone nucleolin in diseases

Storck, S., Shukla, M., Dimitrov, S. & Bouvet, P., 1 Jan 2007, In : Sub-cellular biochemistry. 41, p. 125-144 20 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Histone variant nucleosomes: Structure, function and implication in disease

Boulard, M., Bouvet, P., Kundu, T. K. & Dimitrov, S., 1 Jan 2007, In : Sub-cellular biochemistry. 41, p. 71-89 19 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Role of survivin phosphorylation by Aurora B in mitosis

Delacour-Larose, M., Thi, M. N. H., Dimitrov, S. & Molla, A., 1 Aug 2007, In : Cell Cycle. 6, 15, p. 1878-1885 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2006

Dissection of the unusual structural and functional properties of the variant H2A.Bbd nucleosome

Doyen, C. M., Montel, F., Gautier, T., Menoni, H., Claudet, C., Delacour-Larose, M., Angelov, D., Hamiche, A., Bednar, J., Faivre-Moskalenko, C., Bouvet, P. & Dimitrov, S., 20 Sep 2006, In : EMBO Journal. 25, 18, p. 4234-4244 11 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Mechanism of polymerase II transcription repression by the histone variant macroH2A

Doyen, C. M., An, W., Angelov, D., Bondarenko, V., Mietton, F., Studitsky, V. M., Hamiche, A., Roeder, R. G., Bouvet, P. & Dimitrov, S., Feb 2006, In : Molecular and Cellular Biology. 26, 3, p. 1156-1164 9 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Nucleolin is a histone chaperone with FACT-like activity and assists remodeling of nucleosomes

Angelov, D., Bondarenko, V. A., Almagro, S., Menoni, H., Mongélard, F., Hans, F., Mietton, F., Studitsky, V. M., Hamiche, A., Dimitrov, S. & Bouvet, P., 19 Apr 2006, In : EMBO Journal. 25, 8, p. 1669-1679 11 p.

Research output: Contribution to journalArticle

172 Citations (Scopus)

The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity

Ouararhni, K., Hadj-Slimane, R., Ait-Si-Ali, S., Robin, P., Mietton, F., Harel-Bellan, A., Dimitrov, S. & Hamiche, A., 1 Dec 2006, In : Genes and Development. 20, 23, p. 3324-3336 13 p.

Research output: Contribution to journalArticle

123 Citations (Scopus)

The NH2 tail of the novel histone variant H2BFWT exhibits properties distinct from conventional H2B with respect to the assembly of mitotic chromosomes

Boulard, M., Gautier, T., Mbele, G. O., Gerson, V., Hamiche, A., Angelov, D., Bouvet, P. & Dimitrov, S., Feb 2006, In : Molecular and Cellular Biology. 26, 4, p. 1518-1526 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2005

A small C-terminal sequence of Aurora B is responsible for localization and function

Scrittori, L., Skoufias, D. A., Hans, F., Gerson, V., Sassone-Corsi, P., Dimitrov, S. & Margolis, R. L., Jan 2005, In : Molecular Biology of the Cell. 16, 1, p. 292-305 14 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Histone octamer instability under single molecule experiment conditions

Claudet, C., Angelov, D., Bouvet, P., Dimitrov, S. & Bednar, J., 20 May 2005, In : Journal of Biological Chemistry. 280, 20, p. 19958-19965 8 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Seasonal environmental changes regulate the expression of the histone variant macroH2A in an eurythermal fish

Pinto, R., Ivaldi, C., Reyes, M., Doyen, C., Mietton, F., Mongelard, F., Alvarez, M., Molina, A., Dimitrov, S., Krauskopf, M., Vera, M. I. & Bouvet, P., 24 Oct 2005, In : FEBS Letters. 579, 25, p. 5553-5558 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2004

Distinct dynamics of aurora b and survivin during mitosis

Delacour-Larose, M., Molla, A., Skoufias, D. A., Margolis, R. L. & Dimitrov, S., Nov 2004, In : Cell Cycle. 3, 11, p. 1418-1426 9 p.

Research output: Contribution to journalArticle

Open Access
34 Citations (Scopus)

DNA instructed displacement of histones H2A and H2B at an inducible promoter

Vicent, G. P., Nacht, A. S., Smith, C. L., Peterson, C. L., Dimitrov, S. & Beato, M., 5 Nov 2004, In : Molecular Cell. 16, 3, p. 439-452 14 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Histone variant H2ABbd confers lower stability to the nucleosome

Gautier, T., Abbott, D. W., Molla, A., Verdel, A., Ausio, J. & Dimitrov, S., 1 Jul 2004, In : EMBO Reports. 5, 7, p. 715-720 6 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)

Structural Characterization of MacroH2A Containing Chromatin

Abbott, D. W., Laszczak, M., Lewis, J. D., Su, H., Moore, S. C., Hills, M., Dimitrov, S. & Ausió, J., 10 Feb 2004, In : Biochemistry. 43, 5, p. 1352-1359 8 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

SWI/SNF remodeling and p300-dependent transcription of histone variant H2ABbd nucleosomal arrays

Angelov, D., Verdel, A., An, W., Bondarenko, V., Hans, F., Doyen, C. M., Studitsky, V. M., Hamiche, A., Roeder, R. G., Bouvet, P. & Dimitrov, S., 1 Oct 2004, In : EMBO Journal. 23, 19, p. 3815-3824 10 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

The histone octamer is invisible when NF-κB binds to the nucleosome

Angelov, D., Lenouvel, F., Hans, F., Müller, C. W., Bouvet, P., Bednar, J., Moudrianakis, E. N., Cadet, J. & Dimitrov, S., 8 Oct 2004, In : Journal of Biological Chemistry. 279, 41, p. 42374-42382 9 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

The Mitotic Chromosome Is an Assembly of Rigid Elastic Axes Organized by Structural Maintenance of Chromosomes (SMC) Proteins and Surrounded by a Soft Chromatin Envelope

Almagro, S., Riveline, D., Hirano, T., Houchmandzadeh, B. & Dimitrov, S., 13 Feb 2004, In : Journal of Biological Chemistry. 279, 7, p. 5118-5126 9 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2003

Chromatin and epigenetics: Dynamic organization meets regulated function

Trouche, D., Khochbin, S. & Dimitrov, S., 1 Aug 2003, In : Molecular Cell. 12, 2, p. 281-286 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Individual chromosomes as viscoelastic copolymers

Almagro, S., Dimitrov, S., Hirano, T., Vallade, M. & Riveline, D., 1 Sep 2003, In : Europhysics Letters. 63, 6, p. 908-914 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Phosphorylation of serine 10 in histone H3, what for?

Prigent, C. & Dimitrov, S., 15 Sep 2003, In : Journal of Cell Science. 116, 18, p. 3677-3685 9 p.

Research output: Contribution to journalArticle

317 Citations (Scopus)