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Fingerprint Dive into the research topics where Khaled Machaca is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 11 Similar Profiles
Oocytes Medicine & Life Sciences
Xenopus Medicine & Life Sciences
Meiosis Medicine & Life Sciences
Fertilization Medicine & Life Sciences
Inositol 1,4,5-Trisphosphate Receptors Medicine & Life Sciences
Cell Membrane Medicine & Life Sciences
Endoplasmic Reticulum Medicine & Life Sciences
Ovum Medicine & Life Sciences

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Research Output 1992 2019

Cross-talk between N-terminal and C-terminal domains in stromal interaction molecule 2 (STIM2) determines enhanced STIM2 sensitivity

Emrich, S. M., Yoast, R. E., Xin, P., Zhang, X., Pathak, T., Nwokonko, R., Gueguinou, M. F., Subedi, K. P., Zhou, Y., Ambudkar, I. S., Hempel, N., Machaca, K., Gill, D. L. & Trebak, M., 1 Jan 2019, In : Journal of Biological Chemistry. 294, 16, p. 6318-6332 15 p.

Research output: Contribution to journalArticle

Molecules
Chemical activation
Clustered Regularly Interspaced Short Palindromic Repeats
Cell Membrane
Stromal Interaction Molecule 2
3 Citations (Scopus)

IP3 receptors and store-operated Ca2+ entry: a license to fill

Taylor, C. W. & Machaca, K., 1 Apr 2019, In : Current Opinion in Cell Biology. 57, p. 1-7 7 p.

Research output: Contribution to journalReview article

Inositol 1,4,5-Trisphosphate Receptors
Licensure
Cell Membrane
Ion Channels

miRNA-dependent regulation of STIM1 expression in breast cancer

Kulkarni, R. P., Elmi, A., Alcantara-Adap, E., Hubrack, S. Z., Nader, N., Yu, F., Dib, M., Ramachandran, V., Najafi Shoushtari, H. & Machaca, K., 10 Sep 2019, In : Scientific reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
MicroRNAs
Breast Neoplasms
Cell Line
Ion Channels
Heterografts
1 Citation (Scopus)

Remodeling of ER-plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca2+ influx in mitosis

Yu, F., Hubrack, S. Z., Chakraborty, S., Sun, L., Alcantara-Adap, E., Kulkarni, R., Billing, A., Graumann, J., Taylor, C. W. & Machaca, K., 1 Jan 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 21, p. 10392-10401 10 p.

Research output: Contribution to journalArticle

Open Access
Mitosis
Endoplasmic Reticulum
Phosphorylation
Cell Membrane
Stromal Interaction Molecule 1

Synthesis of TPEN variants to improve cancer cells selective killing capacity

Ramadan, S., Barlog, M., Roach, J., Al-Hashimi, M., Bazzi, H. S. & Machaca, K., 1 Jun 2019, In : Bioorganic Chemistry. 87, p. 366-372 7 p.

Research output: Contribution to journalArticle

Copper
Chelating Agents
Cells
Toxicity
Metals