• 636 Citations
  • 15 h-Index
20052019
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Research Output 2005 2019

  • 636 Citations
  • 15 h-Index
  • 21 Article
  • 4 Review article
  • 1 Comment/debate
2019

Immune checkpoints in the tumor microenvironment

Toor, M., Nair, V., Decock, J. & Elkord, E., 1 Jan 2019, In : Seminars in Cancer Biology.

Research output: Contribution to journalReview article

Tumor Microenvironment
Ligands
Neoplasms
Tumor Escape
Immunosuppressive Agents
2018

A collection of annotated and harmonized human breast cancer transcriptome datasets, including immunologic classification

Miller, L. D., Roelands, J., Decock, J., Boughorbel, S., Rinchai, D., Maccalli, C., Ceccarelli, M., Black, M., Print, C., Chou, J., Presnell, S., Quinn, C., Jithesh, P. V., Syed, N., Al Bader, S. B. J., Bedri, S., Wang, E., Marincola, F. M., Chaussabel, D. J., Kuppen, P. & 2 others, Bedognetti, D. & Hendrickx, W. R., 1 Jan 2018, In : F1000Research. 6, 296.

Research output: Contribution to journalArticle

Transcriptome
Gene expression
Breast Neoplasms
Gene Expression
Genes
17 Citations (Scopus)

NY-ESO-1 based immunotherapy of cancer: Current perspectives

Thomas, R., Al-Khadairi, G., Roelands, J., Hendrickx, W. R., Dermime, S., Bedognetti, D. & Decock, J., 1 May 2018, In : Frontiers in Immunology. 9, MAY, 947.

Research output: Contribution to journalReview article

Immunotherapy
Neoplasms
Testicular Neoplasms
Neoplasm Antigens
Antigens
2017
1 Citation (Scopus)

A collection of annotated and harmonized human breast cancer transcriptome datasets, including immunologic classification

Roelands, J., Decock, J., Boughorbel, S., Rinchai, D., Maccalli, C., Ceccarelli, M., Black, M., Print, C., Chou, J., Presnell, S., Quinn, C., Jithesh, P. V., Syed, N., Al Bader, S. B. J., Bedri, S., Wang, E., Marincola, F. M., Chaussabel, D. J., Kuppen, P., Miller, L. D. & 2 others, Bedognetti, D. & Hendrickx, W. R., 1 Jan 2017, In : F1000Research. 6, 296.

Research output: Contribution to journalComment/debate

Transcriptome
Gene expression
Breast Neoplasms
Gene Expression
Genes
13 Citations (Scopus)

Immunogenomic classification of colorectal cancer and therapeutic implications

Roelands, J., Kuppen, P. J. K., Vermeulen, L., Maccalli, C., Decock, J., Wang, E., Marincola, F. M., Bedognetti, D. & Hendrickx, W. R., 24 Oct 2017, In : International Journal of Molecular Sciences. 18, 10, 2229.

Research output: Contribution to journalReview article

Immune system
immune systems
Colorectal Neoplasms
phenotype
cancer
6 Citations (Scopus)

Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function

Sarper, M., Allen, M. D., Gomm, J., Haywood, L., Decock, J., Thirkettle, S., Ustaoglu, A., Sarker, S. J., Marshall, J., Edwards, D. R. & Jones, J. L., 23 Mar 2017, In : Breast Cancer Research. 19, 1, 33.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 8
Carcinoma, Intraductal, Noninfiltrating
Adhesives
Neoplasms
Hemidesmosomes
2015
13 Citations (Scopus)

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice

Decock, J., Hendrickx, W. R., Thirkettle, S., Gutiérrez-Fernández, A., Robinson, S. D. & Edwards, D. R., 2015, In : Breast Cancer Research. 17, p. 38 1 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 8
Transgenic Mice
Breast Neoplasms
Neoplasm Metastasis
Matrix Metalloproteinases
2014
19 Citations (Scopus)

Metalloproteinase-Dependent and -Independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15

Kelwick, R., Wagstaff, L., Decock, J., Roghi, C., Cooley, L. S., Robinson, S. D., Arnold, H., Gavrilovic, J., Jaworski, D. M., Yamamoto, K., Nagase, H., Seubert, B., Krüger, A. & Edwards, D. R., 1 Jan 2014, In : International Journal of Cancer. 136, 4, p. E14-E26

Research output: Contribution to journalArticle

Thrombospondins
Disintegrins
Metalloproteases
Cell Movement
Breast Neoplasms
2013
26 Citations (Scopus)

Matrix metalloproteinase 8 (collagenase 2) induces the expression of interleukins 6 and 8 in breast cancer cells

Thirkettle, S., Decock, J., Arnold, H., Pennington, C. J., Jaworski, D. M. & Edwards, D. R., 7 Jun 2013, In : Journal of Biological Chemistry. 288, 23, p. 16282-16294 13 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 8
Interleukin-8
Interleukin-6
Cells
Breast Neoplasms
1 Citation (Scopus)

Matrix metalloproteinases: A dual role in breast cancer?

Decock, J., Roghi, C. & Edwards, D. R., 2013, In : Breast Cancer Management. 2, 5, p. 353-356 4 p.

Research output: Contribution to journalReview article

Matrix Metalloproteinases
Breast Neoplasms
7 Citations (Scopus)

Selenium biomarkers in prostate cancer cell lines and influence of selenium on invasive potential of PC3 cells

Hendrickx, W. R., Decock, J., Mulholland, F., Bao, Y. & Fairweather-Tait, S., 31 Dec 2013, In : Frontiers in Oncology. 3 SEP, Article 239.

Research output: Contribution to journalArticle

Selenium
Prostatic Neoplasms
Biomarkers
Cell Line
Thioredoxin Reductase 1
17 Citations (Scopus)

TGF-β-Elicited Induction of Tissue Inhibitor of Metalloproteinases (TIMP)-3 Expression in Fibroblasts Involves Complex Interplay between Smad3, p38α, and ERK1/2

Leivonen, S. K., Lazaridis, K., Decock, J., Chantry, A., Edwards, D. R. & Kähäri, V. M., 28 Feb 2013, In : PLoS One. 8, 2, e57474.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-3
transforming growth factors
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
Transforming Growth Factors
2011
101 Citations (Scopus)

Matrix metalloproteinases: Protective roles in cancer

Decock, J., Thirkettle, S., Wagstaff, L. & Edwards, D. R., 1 Jun 2011, In : Journal of Cellular and Molecular Medicine. 15, 6, p. 1254-1265 12 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Neoplasms
Matrix Metalloproteinase 12
Matrix Metalloproteinase 8
Neoplasm Metastasis
50 Citations (Scopus)

The roles of ADAMTS metalloproteinases in tumorigenesis and metastasis

Wagstaff, L., Kelwick, R., Decock, J. & Edwards, D. R., 1 Jan 2011, In : Frontiers in Bioscience. 16, 5, p. 1861-1872 12 p.

Research output: Contribution to journalArticle

Thrombospondins
Disintegrins
Metalloproteases
Tumors
Carcinogenesis
2009
61 Citations (Scopus)

Axillary lymph node status of operable breast cancers by combined steroid receptor and HER-2 status: Triple positive tumours are more likely lymph node positive

Van Calster, B., Vanden Bempt, I., Drijkoningen, M., Pochet, N., Cheng, J., Van Huffel, S., Hendrickx, W. R., Decock, J., Huang, H. J., Leunen, K., Amant, F., Berteloot, P., Paridaens, R., Wildiers, H., Van Limbergen, E., Weltens, C., Timmerman, D., Van Gorp, T., Smeets, A., Van Den Bogaert, W. & 3 others, Vergote, I., Christiaens, M. R. & Neven, P., 1 Jan 2009, In : Breast Cancer Research and Treatment. 113, 1, p. 181-187 7 p.

Research output: Contribution to journalArticle

Steroid Receptors
Progesterone Receptors
Lymph Nodes
Breast Neoplasms
Neoplasms
19 Citations (Scopus)

Short-term outcome of primary operated early breast cancer by hormone and HER-2 receptors

Brouckaert, O., Pintens, S., Van Belle, V., Van Huffel, S., Camerlynck, E., Amant, F., Leunen, K., Smeets, A., Berteloot, P., Van Limbergen, E., Decock, J., Hendrickx, W. R., Weltens, C., Van Den Bogaert, W., Vanden Bempt, I., Drijkoningen, M., Paridaens, R., Wildiers, H., Vergote, I., Christiaens, M. R. & 1 others, Neven, P., 1 May 2009, In : Breast Cancer Research and Treatment. 115, 2, p. 349-358 10 p.

Research output: Contribution to journalArticle

Hormones
Breast Neoplasms
Staining and Labeling
Steroid Receptors
Neoplasm Genes
2008
11 Citations (Scopus)

Age interacts with the expression of steroid and HER-2 receptors in operable invasive breast cancer

Neven, P., Van Calster, B., Van Den Bempt, I., Van Huffel, S., Van Belle, V., Hendrickx, W. R., Decock, J., Wildiers, H., Paridaens, R., Amant, F., Leunen, K., Berteloot, P., Timmerman, D., Van Limbergen, E., Weltens, C., Van Den Bogaert, W., Smeets, A., Vergote, I., Christiaens, M. R. & Drijkoningen, M., 1 Jul 2008, In : Breast Cancer Research and Treatment. 110, 1, p. 153-159 7 p.

Research output: Contribution to journalArticle

Steroids
Breast Neoplasms
Progesterone Receptors
Steroid Receptors
Odds Ratio
43 Citations (Scopus)

Cathepsin B, cathepsin H, cathepsin X and cystatin C in sera of patients with early-stage and inflammatory breast cancer

Decock, J., Obermajer, N., Vozelj, S., Hendrickx, W. R., Paridaens, R. & Kos, J., 1 Dec 2008, In : International Journal of Biological Markers. 23, 3, p. 161-168 8 p.

Research output: Contribution to journalArticle

Cathepsin H
Cathepsin C
Inflammatory Breast Neoplasms
Cystatin C
Cathepsins
46 Citations (Scopus)

Genetic polymorphisms of matrix metalloproteinases in lung, breast and colorectal cancer

Decock, J., Paridaens, R. & Ye, S., 1 Mar 2008, In : Clinical Genetics. 73, 3, p. 197-211 15 p.

Research output: Contribution to journalArticle

Genetic Polymorphisms
Matrix Metalloproteinases
Colorectal Neoplasms
Lung Neoplasms
Breast Neoplasms
51 Citations (Scopus)

Plasma MMP1 and MMP8 expression in breast cancer: Protective role of MMP8 against lymph node metastasis

Decock, J., Hendrickx, W. R., Vanleeuw, U., Van Belle, V., Van Huffel, S., Christiaens, M. R., Ye, S. & Paridaens, R., 20 Mar 2008, In : BMC Cancer. 8, 77.

Research output: Contribution to journalArticle

Lymph Nodes
Breast Neoplasms
Neoplasm Metastasis
Inflammatory Breast Neoplasms
Cytoprotection
2007
64 Citations (Scopus)

Association of matrix metalloproteinase-8 gene variation with breast cancer prognosis

Decock, J., Long, J. R., Laxton, R. C., Shu, X. O., Hodgkinson, C., Hendrickx, W. R., Pearce, E. G., Gao, Y. T., Pereira, A. C., Paridaens, R., Zheng, W. & Ye, S., 1 Nov 2007, In : Cancer Research. 67, 21, p. 10214-10221 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 8
Alleles
Breast Neoplasms
Single Nucleotide Polymorphism
Neoplasm Metastasis
5 Citations (Scopus)

Loss of nuclear BRCA1 protein staining in normal tissue cells derived from BRCA1 and BRCA2 mutation carriers

De Brakeleer, S., Bogdani, M., De Grève, J., Decock, J., Sermijn, E., Bonduelle, M., Goelen, G. & Teugels, E., 1 Jun 2007, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 619, 1-2, p. 104-112 9 p.

Research output: Contribution to journalArticle

BRCA1 Protein
Nuclear Proteins
Genomic Instability
Staining and Labeling
Mutation
18 Citations (Scopus)

Matrix metalloproteinase expression patterns in luminal A type breast carcinomas

Decock, J., Hendrickx, W. R., Drijkoningen, M., Wildiers, H., Neven, P., Smeets, A. & Paridaens, R., 11 Jun 2007, In : Disease Markers. 23, 3, p. 189-196 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Breast Neoplasms
Ductal Carcinoma
RNA
Tumors
2006
1 Citation (Scopus)
ErbB-2 Receptor
Tumor Biomarkers
In Situ Hybridization
Real-Time Polymerase Chain Reaction
Immunohistochemistry
2005
17 Citations (Scopus)

Plasma gelatinase levels in patients with primary breast cancer in relation to axillary lymph node status, Her2/neu expression and other clinicopathological variables

Decock, J., Hendrickx, W. R., Wildiers, H., Christiaens, M. R., Neven, P., Drijkoningen, M. & Paridaens, R., 1 Nov 2005, In : Clinical and Experimental Metastasis. 22, 6, p. 495-502 8 p.

Research output: Contribution to journalArticle

Gelatinases
Lymph Nodes
Breast Neoplasms
Neoplasms
Neoplasm Metastasis
29 Citations (Scopus)

Proteases and metastasis: Clinical relevance nowadays?

Decock, J., Paridaens, R. & Čufer, T., 1 Nov 2005, In : Current Opinion in Oncology. 17, 6, p. 545-550 6 p.

Research output: Contribution to journalArticle

Plasminogen Activators
Urokinase-Type Plasminogen Activator
Cathepsins
Plasminogen Activator Inhibitor 1
Peptide Hydrolases