• 3777 Citations
  • 35 h-Index
1993 …2020
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Research Output 1993 2020

  • 3777 Citations
  • 35 h-Index
  • 87 Article
  • 4 Review article
  • 2 Letter
  • 1 Chapter
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Article
2005
154 Citations (Scopus)

CD4+ T-cell death induced by infectious and noninfectious HIV-1: Role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis

Herbeuval, J. P., Grivel, J-C. B., Boasso, A., Hardy, A. W., Chougnet, C., Dolan, M. J., Yagita, H., Lifson, J. D. & Shearer, G. M., 15 Nov 2005, In : Blood. 106, 10, p. 3524-3531 8 p.

Research output: Contribution to journalArticle

TNF-Related Apoptosis-Inducing Ligand
TNF-Related Apoptosis-Inducing Ligand Receptors
Interferon Type I
T-cells
Cell death
20 Citations (Scopus)

Differential pathogenesis of primary CCR5-using human immunodeficiency virus type 1 isolates in ex vivo human lymphoid tissue

Karlsson, I., Grivel, J-C. B., Chen, S. S., Karlsson, A., Albert, J., Fenyö, E. M. & Margolis, L. B., Sep 2005, In : Journal of Virology. 79, 17, p. 11151-11160 10 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
HIV-1
Viruses
T-Lymphocytes
Thromboplastin
29 Citations (Scopus)

Inhibition of HIV-1 replication in human lymphoid tissues ex vivo by measles virus

Grivel, J-C. B., Garcia, M., Moss, W. J. & Margolis, L. B., 1 Jul 2005, In : Journal of Infectious Diseases. 192, 1, p. 71-78 8 p.

Research output: Contribution to journalArticle

Measles virus
Lymphoid Tissue
Virus Replication
HIV-1
Virus Diseases
14 Citations (Scopus)

Pertussis toxin B-oligomer dissociates T cell activation and HIV replication in CD4 T cells released from infected lymphoid tissue

Alfano, M., Grivel, J-C. B., Ghezzi, S., Corti, D., Trimarchi, M., Poli, G. & Margolis, L., 1 Jul 2005, In : AIDS. 19, 10, p. 1007-1014 8 p.

Research output: Contribution to journalArticle

Pertussis Toxin
Lymphoid Tissue
HIV
T-Lymphocytes
HIV-1
118 Citations (Scopus)

TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigen-presenting cells

Herbeuval, J. P., Boasso, A., Grivel, J-C. B., Hardy, A. W., Anderson, S. A., Dolan, M. J., Chougnet, C., Lifson, J. D. & Shearer, G. M., 15 Mar 2005, In : Blood. 105, 6, p. 2458-2464 7 p.

Research output: Contribution to journalArticle

TNF-Related Apoptosis-Inducing Ligand
Antigen-Presenting Cells
HIV-1
Tumor Necrosis Factor-alpha
Apoptosis
2004
16 Citations (Scopus)

CXCR4-Tropic HIV-1 Suppresses Replication of CCR5-Tropic HIV-1 in Human Lymphoid Tissue by Selective Induction of CC-Chemokines

Ito, Y., Grivel, J-C. B., Chen, S., Kiselyeva, Y., Reichelderfer, P. & Margolis, L., 1 Feb 2004, In : Journal of Infectious Diseases. 189, 3, p. 506-514 9 p.

Research output: Contribution to journalArticle

CC Chemokines
Lymphoid Tissue
HIV-1
Chemokines
HIV
12 Citations (Scopus)

Depletion of CD4 T lymphocytes in human lymphoid tissue infected ex vivo with doxycycline-dependent HIV-1

Kiselyeva, Y., Ito, Y., Lima, R. G., Grivel, J-C. B., Das, A. T., Berkhout, B. & Margolis, L. B., 15 Oct 2004, In : Virology. 328, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

Doxycycline
Lymphoid Tissue
HIV-1
T-Lymphocytes
HIV
75 Citations (Scopus)

Dual role of prostratin in inhibition of infection and reactivation of human immunodeficiency virus from latency in primary blood lymphocytes and lymphoid tissue

Biancotto, A., Grivel, J-C. B., Gondois-Rey, F., Bettendroffer, L., Vigne, R., Brown, S., Margolis, L. B. & Hirsch, I., Oct 2004, In : Journal of Virology. 78, 19, p. 10507-10515 9 p.

Research output: Contribution to journalArticle

Virus Latency
Lymphoid Tissue
HIV
Lymphocytes
HIV-1
21 Citations (Scopus)

IL-15 alters expression and function of the chemokine receptor CX3CR1 in human NK cells

Sechler, J. M., Barlic, J., Grivel, J-C. B. & Murphy, P. M., Aug 2004, In : Cellular Immunology. 230, 2, p. 99-108 10 p.

Research output: Contribution to journalArticle

Interleukin-15
Chemokine Receptors
Natural Killer Cells
Messenger RNA
Cultured Cells
6 Citations (Scopus)

Noninfectious X4 but not R5 human immunodeficiency virus type 1 virions inhibit humoral immune responses in human lymphoid tissue ex vivo

Fitzgerald, W., Sylwester, A. W., Grivel, J-C. B., Lifson, J. D. & Margolis, L. B., Jul 2004, In : Journal of Virology. 78, 13, p. 7061-7068 8 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
Humoral Immunity
Virion
HIV-1
Virus Diseases
30 Citations (Scopus)

Vpr and Vpu are important for efficient human immunodeficiency virus type 1 replication and CD4+ T-cell depletion in human lymphoid tissue ex vivo

Rücker, E., Grivel, J-C. B., Münch, J., Kirchhoff, F. & Margolis, L., Nov 2004, In : Journal of Virology. 78, 22, p. 12689-12693 5 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
Virus Replication
HIV-1
T-Lymphocytes
vpu Genes
2003
11 Citations (Scopus)

Bystander CD4+ T lymphocytes survive in HIV-infected human lymphoid tissue

Grivel, J-C. B., Biancotto, A., Ito, Y., Lima, R. G. & Margolis, L. B., 1 Mar 2003, In : AIDS Research and Human Retroviruses. 19, 3, p. 211-216 6 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
HIV
T-Lymphocytes
Nevirapine
HIV Infections
98 Citations (Scopus)

Isolation and clonal analysis of human epidermal keratinocyte stem cells in long-term culture

Papini, S., Cecchetti, D., Campani, D., Fitzgerald, W., Grivel, J-C. B., Chen, S., Margolis, L. & Revoltella, R. P., 2003, In : Stem Cells. 21, 4, p. 481-494 14 p.

Research output: Contribution to journalArticle

Keratinocytes
Stem Cells
Skin
Collagen
Fibroblasts
71 Citations (Scopus)

Pathogenic effects of human herpesvirus 6 in human lymphoid tissue ex vivo

Grivel, J-C. B., Santoro, F., Chen, S., Fagá, G., Malnati, M. S., Ito, Y., Margolis, L. & Lusso, P., Aug 2003, In : Journal of Virology. 77, 15, p. 8280-8289 10 p.

Research output: Contribution to journalArticle

Human Herpesvirus 6
Lymphoid Tissue
T-Lymphocytes
Herpesviridae Infections
Chemokine CCL5
9 Citations (Scopus)

Real-time PCR assay of individual human immunodeficiency virus type 1 variants in coinfected human lymphoid tissues

Ito, Y., Grivel, J-C. B. & Margolis, L., 1 May 2003, In : Journal of Clinical Microbiology. 41, 5, p. 2126-2131 6 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
HIV-1
Real-Time Polymerase Chain Reaction
RNA Viruses
Disease Progression
2002
20 Citations (Scopus)

Segregation of R5 and X4 HIV-1 variants to memory T cell subsets differentially expressing CD62L in ex vivo infected human lymphoid tissue

Gondois-Rey, F., Grivel, J-C. B., Biancotto, A., Pion, M., Vigne, R., Margolis, L. B. & Hirsch, I., 14 Jun 2002, In : AIDS. 16, 9, p. 1245-1249 5 p.

Research output: Contribution to journalArticle

T-Lymphocyte Subsets
Lymphoid Tissue
HIV-1
T-Lymphocytes
Lymphocyte Homing Receptors
2001
18 Citations (Scopus)

Coreceptor choice and T cell depletion by R5, X4, and R5X4 HIV-1 variants in CCR5-deficient (CCR5δ32) and normal human lymphoid tissue

Malkevitch, N., McDermott, D. H., Yi, Y., Grivel, J-C. B., Schols, D., De Clercq, E., Murphy, P. M., Glushakova, S., Collman, R. G. & Margolis, L., 15 Mar 2001, In : Virology. 281, 2, p. 239-247 9 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
HIV-1
T-Lymphocytes
In Vitro Techniques
Pharmacology
11 Citations (Scopus)

Human immunodeficiency virus type 1 (hiv-1) non-b subtypes are similar to hiv-1 subtype b in that coreceptor specificity is a determinant of cytopathicity in human lymphoid tissue infected ex vivo

Malkevich, N., Womack, C., Pandya, P., Grivel, J-C. B., Fauci, A. S. & Margolis, L., 2001, In : Journal of Virology. 75, 21, p. 10520-10522 3 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
HIV-1
T-Lymphocytes
Virus Diseases
Viruses
94 Citations (Scopus)

Suppression of CCR5- but not CXCR4-tropic HIV-1 in lymphoid tissue by human herpesvirus 6

Grivel, J-C. B., Ito, Y., Fagà, G., Santoro, F., Shaheen, F., Malnati, M. S., Fitzgerald, W., Lusso, P. & Margolis, L., 2001, In : Nature Medicine. 7, 11, p. 1232-1235 4 p.

Research output: Contribution to journalArticle

Human Herpesvirus 6
Tropics
Lymphoid Tissue
HIV-1
T-cells
2000
15 Citations (Scopus)

Breakdown of tolerance to a neo-self antigen in double transgenic mice in which B cells present the antigen

De Vos, A. F., Fukushima, A., Lobanoff, M. C., Vistica, B. P., Lai, J. C., Grivel, J-C. B., Wawrousek, E. F., Whitcup, S. M. & Gery, I., 1 May 2000, In : Journal of Immunology. 164, 9, p. 4594-4600 7 p.

Research output: Contribution to journalArticle

Autoantigens
Transgenic Mice
B-Lymphocytes
Antigens
Lymphocytes
56 Citations (Scopus)

Human immunodeficiency virus type 1 coreceptor preferences determine target T-cell depletion and cellular tropism in human lymphoid tissue

Grivel, J-C. B., Penn, M. L., Eckstein, D. A., Schramm, B., Speck, R. F., Abbey, N. W., Herndier, B., Margolis, L. & Goldsmith, M. A., 2000, In : Journal of Virology. 74, 11, p. 5347-5351 5 p.

Research output: Contribution to journalArticle

Tropism
Lymphoid Tissue
HIV-1
Lymphocytes
T-Lymphocytes
39 Citations (Scopus)

Human immunodeficiency virus type 1 induces apoptosis in CD4+ but not in CD8+ T cells in ex vivo-infected human lymphoid tissue

Grivel, J. C., Malkevitch, N. & Margolis, L., 2000, In : Journal of Virology. 74, 17, p. 8077-8084 8 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
HIV-1
Apoptosis
T-Lymphocytes
Virus Diseases
8 Citations (Scopus)

Small molecule inhibitor of HIV-1 nuclear import suppresses HIV-1 replication in human lymphoid tissue ex vivo: A potential addition to current anti-HIV drug repertoire

Glushakova, S., Dubrovsky, L., Grivel, J-C. B., Haffar, O. & Bukrinsky, M., Aug 2000, In : Antiviral Research. 47, 2, p. 89-95 7 p.

Research output: Contribution to journalArticle

Anti-HIV Agents
Cell Nucleus Active Transport
Lymphoid Tissue
HIV-1
Pharmaceutical Preparations
1999
151 Citations (Scopus)

CCR5-and CXCR4-tropic HIV-1 are equally cytopathic for their T-cell targets in human lymphoid tissue

Grivel, J-C. B. & Margolis, L. B., 1999, In : Nature Medicine. 5, 3, p. 344-346 3 p.

Research output: Contribution to journalArticle

Tropics
T-cells
Lymphoid Tissue
HIV-1
Tissue
117 Citations (Scopus)

CXCR4 utilization is sufficient to trigger CD4+ T cell depletion in HIV-1-infected human lymphoid tissue

Penn, M. L., Grivel, J-C. B., Schramm, B., Goldsmith, M. A. & Margolis, L., 19 Jan 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 2, p. 663-668 6 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
HIV-1
Viruses
T-Lymphocytes
Chemokine Receptors
56 Citations (Scopus)

Immunization through dermal delivery of protein-encoding DNA: A role for migratory dendritic cells

Bouloc, A., Walker, P., Grivel, J-C. B., Vogel, J. C. & Katz, S. I., 1999, In : European Journal of Immunology. 29, 2, p. 446-454 9 p.

Research output: Contribution to journalArticle

Langerhans Cells
Dendritic Cells
Immunization
Skin
DNA
67 Citations (Scopus)

Nef enhances human immunodeficiency virus replication and responsiveness to interleukin-2 in human lymphoid tissue ex vivo

Glushakova, S., Grivel, J. C., Suryanarayana, K., Meylan, P., Lifson, J. D., Desrosiers, R. & Margolis, L., 1999, In : Journal of Virology. 73, 5, p. 3968-3974 7 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
Virus Replication
Interleukin-2
HIV-1
HIV
87 Citations (Scopus)

Preferential coreceptor utilization and cytopathicity by dual-tropic HIV-1 in human lymphoid tissue ex vivo

Glushakova, S., Yi, Y., Grivel, J-C. B., Singh, A., Schols, D., De Clercq, E., Collman, R. G. & Margolis, L., Sep 1999, In : Journal of Clinical Investigation. 104, 5

Research output: Contribution to journalArticle

Lymphoid Tissue
HIV-1
T-Lymphocytes
Viruses
Cell Line
29 Citations (Scopus)

Structural differences among monoclonal antibodies with distinct fine specificities and kinetic properties

Lavoie, T. B., Mohan, S., Lipschultz, C. A., Grivel, J-C. B., Li, Y., Mainhart, C. R., Kam-Morgan, L. N. W., Drohan, W. N. & Smith-Gill, S. J., Dec 1999, In : Molecular Immunology. 36, 17, p. 1189-1205 17 p.

Research output: Contribution to journalArticle

Egg White
Germ Cells
Monoclonal Antibodies
Genes
Mutation
1998
45 Citations (Scopus)

Blockade of CC chemokine receptor 5 (CCR5)-tropic human immunodeficiency virus-1 replication in human lymphoid tissue by CC chemokines

Margolis, L. B., Glushakova, S., Grivel, J-C. B. & Murphy, P. M., 1 May 1998, In : Journal of Clinical Investigation. 101, 9, p. 1876-1880 5 p.

Research output: Contribution to journalArticle

CCR5 Receptors
CC Chemokines
Lymphoid Tissue
Virus Replication
HIV-1
9 Citations (Scopus)

CD4+ T-lymphocyte depletion in human lymphoid tissue ex vivo is not induced by noninfectious human immunodeficiency virus type 1 virions

Sylwester, A. W., Grivel, J-C. B., Fitzgerald, W., Rossio, J. L., Lifson, J. D. & Margolis, L. B., Nov 1998, In : Journal of Virology. 72, 11, p. 9345-9347 3 p.

Research output: Contribution to journalArticle

Lymphocyte Depletion
Lymphoid Tissue
Virion
HIV-1
T-Lymphocytes
70 Citations (Scopus)

Efficient presentation of multivalent antigens targeted to various cell surface molecules of dendritic cells and surface Ig of antigen-specific B cells

Serre, K., Machy, P., Grivel, J-C. B., Jolly, G., Brun, N., Barbet, J. & Leserman, L., 1 Dec 1998, In : Journal of Immunology. 161, 11, p. 6059-6067 9 p.

Research output: Contribution to journalArticle

Antigen Presentation
Surface Antigens
Dendritic Cells
B-Lymphocytes
Liposomes
99 Citations (Scopus)

Evidence for the HIV-1 phenotype switch as a causal factor in acquired immunodeficiency

Glushakova, S., Grivel, J-C. B., Fitzgerald, W., Sylwester, A., Zimmerberg, J. & Margolis, L. B., 1998, In : Nature Medicine. 4, 3, p. 346-349 4 p.

Research output: Contribution to journalArticle

Tropics
HIV-1
Switches
Phenotype
Viruses
1997

High-resolution epitope mapping of hen egg lysozyme mabs by alanine-scanning mutagenesis

Li, Y., Grivel, J-C. B., Viswanathan, M. & Smith-Gill, 1997, In : FASEB Journal. 11, 9

Research output: Contribution to journalArticle

Epitope Mapping
Mutagenesis
Alanine
Epitopes
Scanning
1995
32 Citations (Scopus)

Different endocytic compartments are involved in the tight association of class II molecules with processed hen egg lysozyme and ribonuclease A in B cells

Escola, J. M., Grivel, J-C. B., Chavrier, P. & Gorvel, J. P., 1995, In : Journal of Cell Science. 108, 6, p. 2337-2345 9 p.

Research output: Contribution to journalArticle

Pancreatic Ribonuclease
B-Lymphocytes
Endosomes
Antigens
Antigen Presentation
1994
5 Citations (Scopus)

Endocytosis and presentation of liposome-associated antigens by B cells

Grivel, J-C. B., Crook, K. & Leserman, L., 1994, In : ImmunoMethods. 4, 3, p. 223-228 6 p.

Research output: Contribution to journalArticle

Endocytosis
Liposomes
B-Lymphocytes
B-Cell Antigen Receptors
Cells
1993
10 Citations (Scopus)

Rapid induction of anti-idiotypic responses to unmodified monoclonal antibodies from syngeneic mice following primary immunization

Grivel, J-C. B., Ferrier, P., Renard, N., Jolly, G., Jarry, T. & Leserman, L., 3 Feb 1993, In : Journal of Immunological Methods. 158, 2, p. 173-182 10 p.

Research output: Contribution to journalArticle

Immunization
Monoclonal Antibodies
Antibodies
Anti-Idiotypic Antibodies
Artifacts