• 1010 Citations
  • 18 h-Index
1993 …2019
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Research Output 1993 2019

  • 1010 Citations
  • 18 h-Index
  • 30 Article
  • 1 Conference contribution
  • 1 Review article
2019
Calreticulin
Endoplasmic Reticulum Stress
Endocytosis
Caveolin 1
Clathrin Heavy Chains
2014
2 Citations (Scopus)
Calreticulin
Proteins
Endoplasmic Reticulum Stress
Apoptosis
Protein Phosphatase 2
2013

Oxidation of selected lipids in low density lipoprotein: Effects on calcium transients in isolated rabbit cardiomyocytes

Liu, K. Z., Massaeli, H., Ramjiawan, B. & Pierce, G. N., 1 Dec 2013, Advanced Bioactive Compounds Countering the Effects of Radiological, Chemical and Biological Agents: Strategies to Counter Biological Damage. p. 83-99 17 p. (NATO Science for Peace and Security Series A: Chemistry and Biology).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lipoproteins
Cholesterol
LDL Lipoproteins
Cardiac Myocytes
Lipids
2011
36 Citations (Scopus)

Involvement of caveolin in probucol-induced reduction in hERG plasma-membrane expression

Guo, J., Li, X., Shallow, H., Xu, J., Yang, T., Massaeli, H., Li, W., Sun, T., Pierce, G. N. & Zhang, S., 1 May 2011, In : Molecular Pharmacology. 79, 5, p. 806-813 8 p.

Research output: Contribution to journalArticle

Probucol
Caveolins
Ether
Cell Membrane
Genes
27 Citations (Scopus)

The role of monoubiquitination in endocytic degradation of human ether-a-go-go-related gene (hERG) channels under low K+ conditions

Sun, T., Guo, J., Shallow, H., Yang, T., Xu, J., Li, W., Hanson, C., Wu, J. G., Li, X., Massaeli, H. & Zhang, S., 25 Feb 2011, In : Journal of Biological Chemistry. 286, 8, p. 6751-6759 9 p.

Research output: Contribution to journalArticle

Ether
Genes
Degradation
Multivesicular Bodies
Ubiquitin
2010
32 Citations (Scopus)

Extracellular K+ is a prerequisite for the function and plasma membrane stability of HERG channels

Massaeli, H., Guo, J., Xu, J. & Zhang, S., 1 Apr 2010, In : Circulation Research. 106, 6, p. 1072-1082 11 p.

Research output: Contribution to journalArticle

Ether
Cell Membrane
Genes
Delayed Rectifier Potassium Channels
Rabbits
27 Citations (Scopus)

Involvement of caveolin in low K+-induced endocytic degradation of cell-surface human ether-a-go-go-related gene (hERG) channels

Massaeli, H., Sun, T., Li, X., Shallow, H., Wu, J., Xu, J., Li, W., Hanson, C., Guo, J. & Zhang, S., 27 Aug 2010, In : Journal of Biological Chemistry. 285, 35, p. 27259-27264 6 p.

Research output: Contribution to journalArticle

Caveolins
Ether
Genes
Caveolin 1
Degradation
2009
102 Citations (Scopus)

Extracellular K+ concentration controls cell surface density of IKr in rabbit hearts and of the HERG channel in human cell lines

Guo, J., Massaeli, H., Xu, J., Jia, Z., Wigle, J. T., Mesaeli, N. & Zhang, S., 1 Sep 2009, In : Journal of Clinical Investigation. 119, 9, p. 2745-2757 13 p.

Research output: Contribution to journalArticle

Ether
Cell Count
Rabbits
Cell Line
Genes
2007
16 Citations (Scopus)

Differential expression and activity of matrix metalloproteinase-2 and -9 in the calreticulin deficient cells

Wu, M., Massaeli, H., Durston, M. & Mesaeli, N., Jul 2007, In : Matrix Biology. 26, 6, p. 463-472 10 p.

Research output: Contribution to journalArticle

Calreticulin
Matrix Metalloproteinase 2
Matrix Metalloproteinase 9
Matrix Metalloproteinase 14
Matrix Metalloproteinases
95 Citations (Scopus)

Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes

Guo, J., Massaeli, H., Li, W., Xu, J., Luo, T., Shaw, J., Kirshenbaum, L. A. & Zhang, S., 1 Jun 2007, In : Journal of Pharmacology and Experimental Therapeutics. 321, 3, p. 911-920 10 p.

Research output: Contribution to journalArticle

Probucol
Long QT Syndrome
Cardiac Myocytes
Ether
Genes
2005
4 Citations (Scopus)

Gene transfer of prostaglandin synthase maintains patency of the newborn lamb arterial duct

Humpl, T., Zaidi, S. H. E., Coe, J. Y., Russell, J., Kaneda, Y., Massaeli, H., Benson, L. N. & Rabinovitch, M., 1 Nov 2005, In : Pediatric Research. 58, 5, p. 976-980 5 p.

Research output: Contribution to journalArticle

Ductus Arteriosus
Prostaglandin-Endoperoxide Synthases
Patent Ductus Arteriosus
Dinoprostone
Transfection
2004
22 Citations (Scopus)

Apolipoprotein D and platelet-derived growth factor-BB synergism mediates vascular smooth muscle cell migration

Leung, W. C. Y., Lawrie, A., Demaries, S., Massaeli, H., Burry, A., Yablonsky, S., Sarjeant, J. M., Fera, E., Rassart, E., Pickering, J. G. & Rabinovitch, M., 23 Jul 2004, In : Circulation Research. 95, 2, p. 179-186 8 p.

Research output: Contribution to journalArticle

Apolipoproteins D
Vascular Smooth Muscle
Smooth Muscle Myocytes
Cell Movement
platelet-derived growth factor BB
2003
37 Citations (Scopus)

Apolipoprotein D Inhibits Platelet-Derived Growth Factor-BB-Induced Vascular Smooth Muscle Cell Proliferated by Preventing Translocation of Phosphorylated Extracellular Signal Regulated Kinase 1/2 to the Nucleus

Sarjeant, J. M., Lawrie, A., Kinnear, C., Yablonsky, S., Leung, W., Massaeli, H., Prichett, W., Veinot, J. P., Rassart, E. & Rabinovitch, M., 1 Dec 2003, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 23, 12, p. 2172-2177 6 p.

Research output: Contribution to journalArticle

Apolipoproteins D
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
Vascular Smooth Muscle
Smooth Muscle Myocytes
7 Citations (Scopus)

Low matrix metalloproteinase levels precede vascular lesion formation in the JCR: LA-cp rat

Wilson, D., Massaeli, H., Russell, J. C., Pierce, G. N. & Zahradka, P., 1 Jul 2003, In : Molecular and Cellular Biochemistry. 249, 1-2, p. 151-155 5 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Blood Vessels
Rats
Secreted Matrix Metalloproteinases
Animals
12 Citations (Scopus)

Native and minimally oxidized low density lipoprotein depress smooth muscle matrix metalloproteinase levels

Wilson, D., Massaeli, H., Pierce, G. N. & Zahradka, P., 1 Jul 2003, In : Molecular and Cellular Biochemistry. 249, 1-2, p. 141-149 9 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Smooth Muscle
Muscle
Blood Vessels
Extracellular Matrix Proteins
55 Citations (Scopus)

OxLDL stimulates cell proliferation through a general induction of cell cycle proteins

Zettler, M. E., Prociuk, M. A., Austria, J. A., Massaeli, H., Zhong, G. & Pierce, G. N., 1 Feb 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 284, 2 53-2

Research output: Contribution to journalArticle

Cell Cycle Proteins
Cell Proliferation
Cell Cycle
Atherosclerosis
Cyclin-Dependent Kinase 4
2002
45 Citations (Scopus)

Thromboxane A2 receptors mediate pulmonary hypertension in 60% oxygen-exposed newborn rats by a cyclooxygenase-independent mechanism

Jankov, R. P., Belcastro, R., Ovcina, E., Lee, J., Massaeli, H., Lye, S. J. & Keith Tanswell, A., 15 Jul 2002, In : American Journal of Respiratory and Critical Care Medicine. 166, 2, p. 208-214 7 p.

Research output: Contribution to journalArticle

Prostaglandin H2 Receptors Thromboxane A2
L 670596
Endothelin-1
Prostaglandin-Endoperoxide Synthases
Pulmonary Hypertension
2001
81 Citations (Scopus)

A novel vascular smooth muscle chymase is upregulated in hypertensive rats

Guo, C., Ju, H., Leung, D., Massaeli, H., Shi, M. & Rabinovitch, M., 1 Jan 2001, In : Journal of Clinical Investigation. 107, 6, p. 703-715 13 p.

Research output: Contribution to journalArticle

Chymases
Vascular Smooth Muscle
Smooth Muscle Myocytes
Angiotensin II
Pulmonary Artery
6 Citations (Scopus)

Increase in nuclear calcium in smooth muscle cells exposed to oxidized low density lipoprotein

Massaeli, H., Hurtado, C., Austria, A. & Pierce, G. N., 1 Jan 2001, In : Free Radical Research. 34, 1, p. 9-16 8 p.

Research output: Contribution to journalArticle

Smooth Muscle Myocytes
Muscle
Cells
Calcium
Vascular Smooth Muscle
2000
16 Citations (Scopus)

Lesions in ryanodine channels in smooth muscle cells exposed to oxidized low density lipoprotein

Massaeli, H., Austria, J. A. & Pierce, G. N., 1 Jan 2000, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 20, 2, p. 328-334 7 p.

Research output: Contribution to journalArticle

Ryanodine
Sarcoplasmic Reticulum
Smooth Muscle Myocytes
Vascular Smooth Muscle
Adenosine Triphosphate
7 Citations (Scopus)

Overexpression of SERCA2 ATPase in vascular smooth muscle cells treated with oxidized low density lipoprotein

Massaeli, H., Austria, J. A. & Pierce, G. N., 4 Jul 2000, In : Molecular and Cellular Biochemistry. 207, 1-2, p. 137-141 5 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Smooth Muscle Myocytes
Adenosine Triphosphatases
Muscle
Cells
1999
28 Citations (Scopus)

Chronic exposure of smooth muscle cells to minimally oxidized LDL results in depressed inositol 1,4,5-trisphosphate receptor density and Ca2+ transients

Massaeli, H., Austria, J. A. & Pierce, G. N., 17 Sep 1999, In : Circulation Research. 85, 6, p. 515-523 9 p.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate Receptors
Smooth Muscle Myocytes
Vascular Smooth Muscle
oxidized low density lipoprotein
low density lipoprotein inhibitor
18 Citations (Scopus)

Oxidized low-density lipoprotein induces cytoskeletal disorganization in smooth muscle cells

Massaeli, H., Hurtado, C., Austria, J. A. & Pierce, G. N., 1 Nov 1999, In : American Journal of Physiology - Heart and Circulatory Physiology. 277, 5 46-5

Research output: Contribution to journalArticle

Smooth Muscle Myocytes
Myosins
Actins
Myofibrils
Smooth Muscle Myosins
53 Citations (Scopus)

The importance of lipid solubility in antioxidants and free radical generating systems for determining lipoprotein peroxidation

Massaeli, H., Sobrattee, S. & Pierce, G. N., 1 Jun 1999, In : Free Radical Biology and Medicine. 26, 11-12, p. 1524-1530 7 p.

Research output: Contribution to journalArticle

Solubility
Lipoproteins
Free Radicals
Antioxidants
Lipids
1998
61 Citations (Scopus)

Susceptibility of LDL to Oxidative Stress in Obstructive Sleep Apnea

Wali, S. O., Bahammam, A. S., Massaeli, H., Pierce, G. N., Iliskovic, N., Singal, P. K. & Kryger, M. H., 1 May 1998, In : Sleep. 21, 3, p. 290-296 7 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
LDL Lipoproteins
Oxidative Stress
Sleep
Antioxidants
1997
8 Citations (Scopus)

Oxidation of nuclear membrane cholesterol inhibits nucleoside triphosphatase activity

Ramjiawan, B., Czubryt, M. P., Massaeli, H., Gilchrist, J. S. C. & Pierce, G. N., 22 Jul 1997, In : Free Radical Biology and Medicine. 23, 4, p. 556-562 7 p.

Research output: Contribution to journalArticle

Nucleoside-Triphosphatase
Nuclear Envelope
Cholesterol
Cholesterol Oxidase
Membranes
1996
16 Citations (Scopus)

The presence and partitioning of calcium binding proteins in hepatic and cardiac nuclei

Czubryt, M. P., Ramjiawan, B., Gilchrist, J. S. C., Massaeli, H. & Pierce, G. N., 1 Jan 1996, In : Journal of Molecular and Cellular Cardiology. 28, 3, p. 455-465 11 p.

Research output: Contribution to journalArticle

Calcium-Binding Proteins
Nuclear Envelope
Liver
Swine
Proteins
1995
51 Citations (Scopus)

Adult cardiomyocytes express functional high-affinity receptors for basic fibroblast growth factor

Liu, L., Pasumarthi, K. B. S., Padua, R. R., Massaeli, H., Fandrich, R. R., Pierce, G. N., Cattini, P. A. & Kardami, E., 1 Jan 1995, In : American Journal of Physiology - Heart and Circulatory Physiology. 268, 5 37-5

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
Cardiac Myocytes
Fibroblast Growth Factor Receptors
Muscle Cells
Myocardium
34 Citations (Scopus)

Involvement of lipoproteins, free radicals, and calcium in cardiovascular disease processes

Massaeli, H. & Pierce, G. N., 1 Jan 1995, In : Cardiovascular Research. 29, 5, p. 597-603 7 p.

Research output: Contribution to journalReview article

Lipoproteins
Free Radicals
Cardiovascular Diseases
Calcium
Sarcoplasmic Reticulum
1994
4 Citations (Scopus)

Involvement of lipoproteins, free radicals, and calcium in cardiovascular disease processes

Massaeli, H. & Pierce, G. N., 1 Sep 1994, In : Cardiovascular Research. 28, 9, p. 597-603 7 p.

Research output: Contribution to journalArticle

Lipoproteins
Free Radicals
Cardiovascular Diseases
Calcium
Sarcoplasmic Reticulum
1993
75 Citations (Scopus)

Modulation of cardiac performance by amiloride and several selected derivatives of amiloride

Pierce, G. N., Cole, W. C., Liu, K., Massaeli, H., Maddaford, T. G., Yi Jing Chen, J. C., McPherson, C. D., Jain, S. & Sontag, D., 1 Jan 1993, In : Journal of Pharmacology and Experimental Therapeutics. 265, 3, p. 1280-1291 12 p.

Research output: Contribution to journalArticle

Amiloride
Pharmaceutical Preparations
Perfusion
Action Potentials
Cardiac Myocytes
33 Citations (Scopus)

The action of oxidized low density lipoprotein on calcium transients in isolated rabbit cardiomyocytes

Liu, K., Massaeli, H. & Pierce, G. N., 9 Mar 1993, In : Journal of Biological Chemistry. 268, 6, p. 4145-4151 7 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Rabbits
Calcium
Malondialdehyde
Free Radicals