• 782 Citations
  • 13 h-Index
20082019

Research output per year

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Research Output

2019

Akt-activated endothelium promotes ovarian cancer proliferation through notch activation

Hoarau, J., Touboul, C., Halabi, N., Blot-Dupin, M., Lis, R., Abi Khalil, C., Rafii, S., Tabrizi, A. R. & Pasquier, J., 10 Jun 2019, In : Journal of translational medicine. 17, 1, 194.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Anti-proliferative effects of mesenchymal stem cells (MSCs) derived from multiple sources on ovarian cancer cell lines: An in-vitro experimental study

Abi Khalil, C., Moussa, M., Azar, A., Tawk, J., Habbouche, J., Salameh, R., Ibrahim, A. & Alaaeddine, N., 27 Jul 2019, In : Journal of Ovarian Research. 12, 1, 70.

Research output: Contribution to journalArticle

Open Access

Impact of Diabetes Mellitus on Survival in Patients Bridged to Transplantation with Left Ventricular Assist Devices in the United States

Al-Kindi, S. G., Al-Suwaidi, J., Jayyousi, A., Oliveira, G. H. & Abi Khalil, C., 1 Aug 2019, In : ASAIO journal (American Society for Artificial Internal Organs : 1992). 65, 6, p. 587-592 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Mitochondrial-derived peptides are down regulated in diabetes subjects

Ramanjaneya, M., Bettahi, I., Jerobin, J., Chandra, P., Abi Khalil, C., Skarulis, M., Lawrence Atkin, S. & Abou-Samra, A. B., 1 Jan 2019, In : Frontiers in Endocrinology. 10, MAY, 331.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

The association of diabetes, atrial fibrillation and ventricular arrhythmias

Sabayon, M. D., Abi Khalil, C., Sabra, M., Zouein, F. A. & Refaat, M. M., 1 Jan 2019, In : Journal Medical Libanais. 67, 1, p. 28-33 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome

Arasaratnam, D., Bell, K. M., Sim, C. B., Koutsis, K., Anderson, D. J., Qian, E. L., Stanley, E. G., Elefanty, A. G., Cheung, M. M., Oshlack, A., White, A. J., Khalil, C. A., Hudson, J. E., Porrello, E. R. & Elliott, D. A., 1 Dec 2019, In : Scientific reports. 9, 1, 15928.

Research output: Contribution to journalArticle

Open Access

Whole-methylome analysis of circulating monocytes in acute diabetic Charcot foot reveals differentially methylated genes involved in the formation of osteoclasts

Pasquier, J., Spurgeon, M., Bradic, M., Thomas, B., Robay, A., Chidiac, O., DIb, M. J., Turjoman, R., Liberska, A., Staudt, M., Fakhro, K. A., Menzies, R., Jayyousi, A., Zirie, M., Suwaidi, J. A., Malik, R. A., Talal, T., Rafii, A., Mezey, J., Rodriguez-Flores, J. & 2 others, Crystal, R. G. & Khalil, C. A., Feb 2019, In : Epigenomics. 11, 3, p. 281-296 16 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018
1 Citation (Scopus)

Cardiac Complications of Diabetes

Abi Khalil, C., Al Suwaidi, J., Refaat, M. & Mohammedi, K., 1 Jan 2018, In : BioMed Research International. 2018, 1 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)

Corneal confocal microscopy detects severe small fiber neuropathy in diabetic patients with Charcot neuroarthropathy

Khan, A., Petropoulos, I. N., Ponirakis, G., Menzies, R. A., Chidiac, O., Pasquier, J., Abi Khalil, C., Talal, T. K. & Malik, R., 1 Jan 2018, (Accepted/In press) In : Journal of Diabetes Investigation.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Differentially expressed circulating microRNAs in the development of acute diabetic Charcot foot

Pasquier, J., Ramachandran, V., Abu-Qaoud, MD. R., Thomas, B., Benurwar, M. J., Chidiac, O., Hoarau, J., Robay, A., Fakhro, K. A. M. A., Menzies, R. A., Jayyousi, A., Zirie, M., Al Suwaidi, J., Malik, R., Talal, T. K., Najafi, H., Tabrizi, A. R. & Abi Khalil, C., 1 Oct 2018, In : Epigenomics. 10, 10, p. 1267-1278 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Exome sequencing-based identification of novel type 2 diabetes risk allele loci in the Qatari population

O’Beirne, S. L., Salit, J., Rodriguez-Flores, J. L., Staudt, M. R., Khalil, C. A., Fakhro, K. A., Robay, A., Ramstetter, M. D., Malek, J. A., Zirie, M., Jayyousi, A., Badii, R., Al-Marri, A. A. N., Bener, A., Mahmoud, M., Chiuchiolo, M. J., Al-Shakaki, A., Chidiac, O., Stadler, D., Mezey, J. G. & 1 others, Crystal, R. G., Sep 2018, In : PloS one. 13, 9, e0199837.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Point-of-care whole-exome sequencing of idiopathic male infertility

Fakhro, K. A. M. A., Elbardisi, H., Arafa, M., Robay, A., Rodriguez-Flores, J. L., Al-Shakaki, A., Syed, N., Mezey, J. G., Abi Khalil, C., Malek, J., Al-Ansari, A., Al Said, S. & Crystal, R., 1 Nov 2018, In : Genetics in Medicine. 20, 11, p. 1365-1373 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

β-Blockers on Discharge From Acute Atrial Fibrillation Are Associated With Decreased Mortality and Lower Cerebrovascular Accidents in Patients With Heart Failure and Reduced Ejection Fraction

Abi Khalil, C., Zubaid, M., Asaad, N., Rashed, W. A., Hamad, A. K., Singh, R. & Al Suwaidi, J., 1 Apr 2018, In : Angiology. 69, 4, p. 316-322 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Beta-blockers are associated with decreased in-hospital mortality and stroke in acute decompensated heart failure: Findings from a retrospective analysis of a 22-year registry in the middle east (1991-2013)

Abi Khalil, C., Al Suwaidi, J., Singh, R., Asaad, N., Abushahba, G., Kunju, U., Al-Qahtani, A. & AlBinali, H. A., 2017, In : Current Vascular Pharmacology. 15, 1, p. 77-83 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
8 Citations (Scopus)

Coculturing with endothelial cells promotes in vitro maturation and electrical coupling of human embryonic stem cell–derived cardiomyocytes

Pasquier, J., Gupta, R., Rioult, D., Hoarau-Véchot, J., Courjaret, R., Machaca, K., Al Suwaidi, J., Stanley, E. G., Rafii, S., Elliott, D. A., Abi Khalil, C. & Rafii, A., Jun 2017, In : Journal of Heart and Lung Transplantation. 36, 6, p. 684-693 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Investigating palpitations: The role of Holter monitoring and loop recorders

Abi Khalil, C., Haddad, F. & Al Suwaidi, J., 1 Jan 2017, In : BMJ (Online). 358, j3123.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Macrovascular Complications in Patients with Diabetes and Prediabetes

Huang, D., Refaat, M., Mohammedi, K., Jayyousi, A., Al Suwaidi, J. & Abi Khalil, C., 1 Jan 2017, In : BioMed Research International. 2017, 7839101.

Research output: Contribution to journalReview article

33 Citations (Scopus)

Non-withdrawal of beta blockers in acute decompensated chronic and de novo heart failure with reduced ejection fraction in a prospective multicentre study of patients with acute heart failure in the Middle East

Abi Khalil, C., Sulaiman, K., Mahfoud, Z., Singh, R., Asaad, N., Alhabib, K. F., Alsheikh-Ali, A., Al-Jarallah, M., Bulbanat, B., Almahmeed, W., Ridha, M., Bazargani, N., Amin, H., Al-Motarreb, A., Faleh, H. A., Elasfar, A., Panduranga, P. & Suwaidi, J. A., 1 Jul 2017, In : BMJ Open. 7, 7, e014915.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Platelet rich plasma (PRP) induces chondroprotection via increasing autophagy, anti-inflammatory markers, and decreasing apoptosis in human osteoarthritic cartilage

Moussa, M., Lajeunesse, D., Hilal, G., El Atat, O., Haykal, G., Serhal, R., Chalhoub, A., Abi Khalil, C. & Alaaeddine, N., 1 Mar 2017, In : Experimental Cell Research. 352, 1, p. 146-156 11 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

The landscape of glucose-lowering therapy and cardiovascular outcomes: From barren land to metropolis

Nasrallah, M. P., Abi Khalil, C. & Refaat, M. M., 1 Jan 2017, In : BioMed Research International. 2017, 9257930.

Research output: Contribution to journalReview article

1 Citation (Scopus)

β-Blocker therapy prior to admission for acute coronary syndrome in patients without heart failure or left ventricular dysfunction improves in-hospital and 12-Month Outcome: Results from the GULF-RACE 2 (Gulf Registry of Acute Coronary Events-2)

Abi Khalil, C., AlHabib, K. F., Singh, R., Asaad, N., Alfaleh, H., Alsheikh-Ali, A. A., Sulaiman, K., Alshamiri, M., Alshaer, F., AlMahmeed, W. & Al Suwaidi, J. A., 1 Dec 2017, In : Journal of the American Heart Association. 6, 12, e007631.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2016

BMI is inversely correlated to the risk of mortality in patients with type 2 diabetes hospitalized for acute heart failure: Findings from the Gulf aCute heArt failuRE (Gulf-CARE) registry

Abi Khalil, C., Sulaiman, K., Singh, R., Jayyousi, A., Asaad, N., AlHabib, K. F., Alsheikh-Ali, A., Al-Jarallah, M., Bulbanat, B., AlMahmeed, W., Dargham, S., Ridha, M., Bazargani, N., Amin, H., Al-Motarreb, A., AlFaleh, H., Elasfar, A., Panduranga, P. & Al Suwaidi, J., 10 Dec 2016, (Accepted/In press) In : International Journal of Cardiology.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Cardiovascular Disorders and Epigenetics

Abi Khalil, C., 1 Jul 2016, Medical Epigenetics. Elsevier Inc., p. 243-256 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Coronary artery disease prevalence and outcome in patients hospitalized with acute heart failure: an observational report from seven Middle Eastern countries

Salam, A. M., Sulaiman, K., Al-Zakwani, I., Alsheikh-Ali, A., Aljaraallah, M., Al Faleh, H., Elasfar, A., Panduranga, P., Singh, R., Abi Khalil, C. & Al Suwaidi, J., 1 Dec 2016, In : Hospital practice (1995). 44, 5, p. 242-251 10 p.

Research output: Contribution to journalArticle

Correction: Type 2 diabetes risk allele loci in the Qatari population (PLoS ONE (2016) 11:7 (e0156834) DOI: 10.1371/journal.pone.0156834)

O'Beirne, S. L., Salit, J., Rodriguez-Flores, J. L., Staudt, M. R., Khalil, C. A., Fakhro, K. A., Robay, A., Ramstetter, M. D., Al-Azwani, I. K., Malek, J. A., Zirie, M., Jayyousi, A., Badii, R., Al-Marri, A. A. N., Chiuchiolo, M. J., Al-Shakaki, A., Chidiac, O., Gharbiah, M., Bener, A., Stadler, D. & 3 others, Hackett, N. R., Mezey, J. G. & Crystal, R. G., 1 Aug 2016, In : PLoS One. 11, 8, e0161910.

Research output: Contribution to journalComment/debate

Indigenous Arabs are descendants of the earliest split from ancient Eurasian populations

Rodriguez-Flores, J. L., Fakhro, K., Agosto-Perez, F., Ramstetter, M. D., Arbiza, L., Vincent, T. L., Robay, A., Malek, J. A., Suhre, K., Chouchane, L., Badii, R., Al-Marri, A. A. N., Khalil, C. A., Zirie, M., Jayyousi, A., Salit, J., Keinan, A., Clark, A. G., Crystal, R. G. & Mezey, J. G., Feb 2016, In : Genome Research. 26, 2, p. 151-162 12 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

The Qatar genome: A population-specific tool for precision medicine in the Middle East

Fakhro, K. A. M. A., Staudt, M. R., Ramstetter, M. D., Robay, A., Malek, J., Badii, R., Al-Marri, A. A. N., Abi Khalil, C., Al-Shakaki, A., Chidiac, O., Stadler, D., Zirie, M., Jayyousi, A., Salit, J., Mezey, J. G., Crystal, R. & Rodriguez-Flores, J. L., 30 Jun 2016, In : Human Genome Variation. 3, 16016.

Research output: Contribution to journalArticle

Open Access
28 Citations (Scopus)

Type 2 diabetes risk allele loci in the Qatari population

O'Beirne, S. L., Salit, J., Rodriguez-Flores, J. L., Staudt, M. R., Abi Khalil, C., Fakhro, K. A. M. A., Robay, A., Ramstetter, M. D., Al Azwani, I., Malek, J., Zirie, M., Jayyousi, A., Badii, R., Al-Nabet Al-marri, A., Chiuchiolo, M. J., Al-Shakaki, A., Chidiac, O., Gharbiah, M., Bener, A., Stadler, D. & 3 others, Hackett, N. R., Mezey, J. G. & Crystal, R., 1 Jul 2016, In : PLoS One. 11, 7, e0156834.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2015

Cardiovascular disease research activity in the Middle East: A bibliometric analysis

Kindi, S., Juhaishi, T., Abi Khalil, C., Taheri, S. & Haddad, F., Jun 2015, In : Therapeutic Advances in Cardiovascular Disease. 9, 3, p. 70-76 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Epigenetics and Cardiovascular Disease in Diabetes

Pasquier, J., Hoarau, J., Fakhro, K. A. M. A., Tabrizi, A. R. & Abi Khalil, C., 1 Dec 2015, In : Current Diabetes Reports. 15, 12, 108.

Research output: Contribution to journalReview article

20 Citations (Scopus)

Heart transplantation of Middle Eastern patients in the United States: A brief report from the UNOS database

Al-Kindi, S. G., El-Assaad, I., Abi Khalil, C. & Oliveira, G. H., 1 Sep 2015, In : Journal of Heart and Lung Transplantation. 34, 9, p. 1219-1220 2 p., 6045.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Kidney dysfunction in adult offspring exposed in utero to type 1 diabetes is associated with alterations in genome-wide DNA methylation

Gautier, J. F., Porcher, R., Khalil, C. A., Bellili-Munoz, N., Fetita, L. S., Travert, F., Choukem, S. P., Riveline, J. P., Hadjadj, S., Larger, E., Boudou, P., Blondeau, B., Roussel, R., Ferré, P., Ravussin, E., Rouzet, F. & Marre, M., 10 Aug 2015, In : PloS one. 10, 8, e0134654.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2014

Glucose restriction decreases telomerase activity and enhances its inhibitor response on breast cancer cells: Possible extra-telomerase role of BIBR 1532

Wardi, L., Alaaeddine, N., Raad, I., Sarkis, R., Serhal, R., Khalil, C. & Hilal, G., 4 Jul 2014, In : Cancer Cell International. 14, 1, 60.

Research output: Contribution to journalArticle

13 Citations (Scopus)

The emerging role of epigenetics in cardiovascular disease

Abi Khalil, C., Jul 2014, In : Therapeutic Advances in Chronic Disease. 5, 4, p. 178-187 10 p.

Research output: Contribution to journalReview article

53 Citations (Scopus)
2012

Cause-specific mortality in diabetes: Recent changes in trend mortality

Khalil, C. A., Roussel, R., Mohammedi, K., Danchin, N. & Marre, M., 1 Jun 2012, In : European Journal of Preventive Cardiology. 19, 3, p. 374-381 8 p.

Research output: Contribution to journalReview article

51 Citations (Scopus)

Dietary fat intake and polymorphisms at the PPARG locus modulate BMI and type 2 diabetes risk in the D.E.S.I.R. prospective study

Lamri, A., Abi Khalil, C., Jaziri, R., Velho, G., Lantieri, O., Vol, S., Froguel, P., Balkau, B., Marre, M. & Fumeron, F., 1 Feb 2012, In : International Journal of Obesity. 36, 2, p. 218-224 7 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2011

Dairy consumption and the incidence of hyperglycemia and the metabolic syndrome: Results from a French prospective study, data from the epidemiological study on the insulin resistance syndrome (DESIR)

Fumeron, F., Lamri, A., Abi Khalil, C., Jaziri, R., Porchay-BALDÉRELLI, I., Lantieri, O., Vol, S., Balkau, B., Marre, M., Ducimetière, P., Eschwège, E., Alhenc-Gelas, F., Gallois, Y., Girault, A., Bonnet, F., Froguel, P., Cogneau, J., Born, C., Caces, E., Cailleau, M. & 3 others, Moreau, J. G., Rakotozafy, F. & Tichet, J., 1 Apr 2011, In : Diabetes care. 34, 4, p. 813-817 5 p.

Research output: Contribution to journalArticle

122 Citations (Scopus)

Hyperadiponectinemia is independent of kidney function, diabetes duration, and control in type 1 diabetic patients without microangiopathy

Khalil, C. A., Mohammedi, K., Aubert, R., Jaoude, E. A., Travert, F., Hadjadj, S., Fumeron, F., Roussel, R. & Marre, M., 1 Mar 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 3, p. E485-E487

Research output: Contribution to journalArticle

5 Citations (Scopus)

Intensifying glycaemic control with insulin reduces adiponectin and its HMW isoform moderately in type 2, but not in type 1, diabetes

Abi Khalil, C., Mohammedi, K., Aubert, R., Travert, F., Hadjadj, S., Roussel, R., Fumeron, F. & Marre, M., 1 Jun 2011, In : Diabetes and Metabolism. 37, 3, p. 259-261 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Type B insulin resistance syndrome associated with an immune reconstitution inflammatory syndrome in an HIV-infected woman

Mohammedi, K., Roussel, R., El Dbouni, O., Potier, L., Khalil, C. A., Capel, E., Vigouroux, C., Caron-Debarle, M., Capeau, J. & Marre, M., 1 Apr 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 4, p. E653-E657

Research output: Contribution to journalArticle

9 Citations (Scopus)

Use and utility of Ankle brachial index in patients with diabetes

Potier, L., Abi Khalil, C., Mohammedi, K. & Roussel, R., 3 Feb 2011, In : European Journal of Vascular and Endovascular Surgery. 41, 1, p. 110-116 7 p.

Research output: Contribution to journalReview article

130 Citations (Scopus)
2010

Fetal exposure to maternal type 1 diabetes is associated with renal dysfunction at adult age

Khalil, C. A., Travert, F., Fetita, S., Rouzet, F., Porcher, R., Riveline, J. P., Hadjadj, S., Larger, E., Roussel, R., Vexiau, P., Le Guludec, D., Gautier, J. F. & Marre, M., 1 Oct 2010, In : Diabetes. 59, 10, p. 2631-2636 6 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2008
48 Citations (Scopus)