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Research Output 1992 2016

  • 3459 Citations
  • 27 h-Index
  • 37 Article
  • 2 Review article
  • 1 Comment/debate
Article
594 Citations (Scopus)

A chromatin remodelling complex involved in transcription and DNA processing

Shen, X., Mizuguchi, G., Hamiche, A. & Carl, W., 3 Aug 2000, In : Nature. 406, 6795, p. 541-544 4 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
DNA Helicases
Adenosine Triphosphatases
DNA Damage
Chromatin
103 Citations (Scopus)

ANP32E is a histone chaperone that removes H2A.Z from chromatin

Obri, A., Ouararhni, K., Papin, C., Diebold, M. L., Padmanabhan, K., Marek, M., Stoll, I., Roy, L., Reilly, P. T., Mak, T. W., Dimitrov, S., Romier, C. & Hamiche, A., 2014, In : Nature. 505, 7485, p. 648-653 6 p.

Research output: Contribution to journalArticle

Histone Chaperones
Histones
Chromatin
Nucleosomes
Chromatin Immunoprecipitation
167 Citations (Scopus)

Argonaute proteins couple chromatin silencing to alternative splicing

Ameyar-Zazoua, M., Rachez, C., Souidi, M., Robin, P., Fritsch, L., Young, R., Morozova, N., Fenouil, R., Descostes, N., Andrau, J. C., Mathieu, J., Hamiche, A., Ait-Si-Ali, S., Muchardt, C., Batsché, E. & Harel-Bellan, A., Oct 2012, In : Nature Structural and Molecular Biology. 19, 10, p. 998-1005 8 p.

Research output: Contribution to journalArticle

Argonaute Proteins
Alternative Splicing
Chromatin
RNA Polymerase II
Spliceosomes
70 Citations (Scopus)

ATP-dependent chromatin remodeling is required for base excision repair in conventional but not in variant H2A.Bbd nucleosomes

Menoni, H., Gasparutto, D., Hamiche, A., Cadet, J., Dimitrov, S., Bouvet, P. & Angelov, D., Sep 2007, In : Molecular and Cellular Biology. 27, 17, p. 5949-5956 8 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Nucleosomes
DNA Repair
Adenosine Triphosphate
Histones
265 Citations (Scopus)

ATP-dependent histone octamer sliding mediated by the chromatin remodeling complex NURF

Hamiche, A., Sandaltzopoulos, R., Gdula, D. A. & Wu, C., 25 Jun 1999, In : Cell. 97, 7, p. 833-842 10 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Nucleosomes
Histones
Chromatin
Adenosine Triphosphate
4 Citations (Scopus)
Histones
Conformations
Nucleosomes
Substitution reactions
Iodoacetamide
12 Citations (Scopus)

Chromatin reconstitution on small DNA rings. V. DNA thermal flexibility of single nucleosomes

Hamiche, A. & Prunell, A., 20 Nov 1992, In : Journal of Molecular Biology. 228, 2, p. 327-337 11 p.

Research output: Contribution to journalArticle

Nucleosomes
Chromatin
Hot Temperature
DNA
Base Pairing
28 Citations (Scopus)

Cracking the ANP32 whips: Important functions, unequal requirement, and hints at disease implications

Reilly, P. T., Yu, Y., Hamiche, A. & Wang, L., 1 Nov 2014, In : BioEssays. 36, 11, p. 1062-1071 10 p.

Research output: Contribution to journalArticle

Leucine
Phosphoprotein Phosphatases
Phosphoproteins
Caspases
Chromatin
71 Citations (Scopus)

Dissection of the unusual structural and functional properties of the variant H2A.Bbd nucleosome

Doyen, C. M., Montel, F., Gautier, T., Menoni, H., Claudet, C., Delacour-Larose, M., Angelov, D., Hamiche, A., Bednar, J., Faivre-Moskalenko, C., Bouvet, P. & Dimitrov, S., 20 Sep 2006, In : EMBO Journal. 25, 18, p. 4234-4244 11 p.

Research output: Contribution to journalArticle

Dissection
Nucleosomes
Histones
Atomic Force Microscopy
Chromatin
51 Citations (Scopus)

DNA at the Entry-Exit of the Nucleosome Observed by Cryoelectron Microscopy

Furrer, P., Bednar, J., Dubochet, J., Hamiche, A. & Prunell, A., May 1995, In : Journal of Structural Biology. 114, 3, p. 177-183 7 p.

Research output: Contribution to journalArticle

Cryoelectron Microscopy
Nucleosomes
DNA
Chromatin
164 Citations (Scopus)

Dual functions of largest NURF subunit NURF301 in nucleosome sliding and transcription factor interactions

Xiao, H., Sandaltzopoulos, R., Wang, H. M., Hamiche, A., Ranallo, R., Lee, K. M., Fu, D. & Wu, C., 2001, In : Molecular Cell. 8, 3, p. 531-543 13 p.

Research output: Contribution to journalArticle

Nucleosomes
Transcription Factors
HMGA Proteins
Recombinant Proteins
Adenosine Triphosphatases
13 Citations (Scopus)

FACT Assists Base Excision Repair by Boosting the Remodeling Activity of RSC

Charles Richard, J. L., Shukla, M. S., Menoni, H., Ouararhni, K., Lone, I. N., Roulland, Y., Papin, C., Ben Simon, E., Kundu, T., Hamiche, A., Angelov, D. & Dimitrov, S., 1 Jul 2016, In : PLoS Genetics. 12, 7, e1006221.

Research output: Contribution to journalArticle

DNA repair
DNA Repair
repair
Chromatin Assembly and Disassembly
chromatin
39 Citations (Scopus)

GAL4 directs nucleosome sliding induced by NURF

Kang, J. G., Hamiche, A. & Wu, C., 15 Mar 2002, In : EMBO Journal. 21, 6, p. 1406-1413 8 p.

Research output: Contribution to journalArticle

Nucleosomes
DNA
Chromatin Assembly and Disassembly
Dialysis
Transcription
12 Citations (Scopus)

H1-nucleosome interactions and their functional implications

Bednar, J., Hamiche, A. & Dimitrov, S., 1 Mar 2016, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1859, 3, p. 436-443 8 p.

Research output: Contribution to journalArticle

Nucleosomes
Histones
Chromatin
Gene expression regulation
Fibers
98 Citations (Scopus)

HAMLET Interacts with Histones and Chromatin in Tumor Cell Nuclei

Düringer, C., Hamiche, A., Gustafsson, L., Kimura, H. & Svanborg, C., 24 Oct 2003, In : Journal of Biological Chemistry. 278, 43, p. 42131-42135 5 p.

Research output: Contribution to journalArticle

Cell Nucleus
Histones
Chromatin
Tumors
Cells
19 Citations (Scopus)

Histone deacetylase inhibitors promote the tumoricidal effect of HAMLET

Brest, P., Gustafsson, M., Mossberg, A. K., Gustafsson, L., Duringer, C., Hamiche, A. & Svanborg, C., 1 Dec 2007, In : Cancer Research. 67, 23, p. 11327-11334 8 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Histones
Acetylation
Chromatin
Neoplasms
124 Citations (Scopus)

Histone tails modulate nucleosome mobility and regulate ATP-dependent nucleosome sliding by NURF

Hamiche, A., Kang, J. G., Dennis, C., Xiao, H. & Wu, C., 4 Dec 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 25, p. 14316-14321 6 p.

Research output: Contribution to journalArticle

Nucleosomes
Histones
Tail
Adenosine Triphosphate
Catalysis
123 Citations (Scopus)
Centromere
Histones
Vertebrates
Kinetochores
centromere protein A
105 Citations (Scopus)
Superhelical DNA
Nucleosomes
Histones
DNA
Proteins
146 Citations (Scopus)

Linker histone-dependent DNA structure in linear mononucleosomes

Hamiche, A., Schultz, P., Ramakrishnan, V., Oudet, P. & Prunell, A., 22 Mar 1996, In : Journal of Molecular Biology. 257, 1, p. 30-42 13 p.

Research output: Contribution to journalArticle

Histones
DNA
Nucleosomes
Cryoelectron Microscopy
Static Electricity
101 Citations (Scopus)

Mechanism of polymerase II transcription repression by the histone variant macroH2A

Doyen, C. M., An, W., Angelov, D., Bondarenko, V., Mietton, F., Studitsky, V. M., Hamiche, A., Roeder, R. G., Bouvet, P. & Dimitrov, S., Feb 2006, In : Molecular and Cellular Biology. 26, 3, p. 1156-1164 9 p.

Research output: Contribution to journalArticle

Histones
Nucleosomes
Acetylation
Transcriptional Activation
Chromatin
6 Citations (Scopus)

Methods for Analysis of Nucleosome Sliding by Drosophila NURF

Hamiche, A. & Xiao, H., 2004, In : Methods in Enzymology. 377, p. 353-363 11 p.

Research output: Contribution to journalArticle

Nucleosomes
6 Citations (Scopus)

Methods for chromatin assembly and remodeling

Duband-Goulet, I., Ouararhni, K. & Hamiche, A., May 2004, In : Methods. 33, 1, p. 12-17 6 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Nucleosomes
Chromatin
DNA
Gels
19 Citations (Scopus)

Molecular basis and specificity of H2A.Z-H2B recognition and deposition by the histone chaperone YL1

Latrick, C. M., Marek, M., Ouararhni, K., Papin, C., Stoll, I., Ignatyeva, M., Obri, A., Ennifar, E., Dimitrov, S., Romier, C. & Hamiche, A., 5 Apr 2016, In : Nature Structural and Molecular Biology. 23, 4, p. 309-316 8 p.

Research output: Contribution to journalArticle

Histone Chaperones
Chromatin Assembly and Disassembly
Nucleosomes
Histones
Chromatin
172 Citations (Scopus)

Nucleolin is a histone chaperone with FACT-like activity and assists remodeling of nucleosomes

Angelov, D., Bondarenko, V. A., Almagro, S., Menoni, H., Mongélard, F., Hans, F., Mietton, F., Studitsky, V. M., Hamiche, A., Dimitrov, S. & Bouvet, P., 19 Apr 2006, In : EMBO Journal. 25, 8, p. 1669-1679 11 p.

Research output: Contribution to journalArticle

Histone Chaperones
Nucleosomes
Transcription
Chromatin Assembly and Disassembly
Dimers
37 Citations (Scopus)

Octamer displacement and redistribution in transcription of single nucleosomes

O'donohue, M. F., Duband-goulet, I., Hamiche, A. & Prunell, A., 25 Mar 1994, In : Nucleic Acids Research. 22, 6, p. 937-945 9 p.

Research output: Contribution to journalArticle

Nucleosomes
Gels
RNA
Sea Urchins
Xenopus
34 Citations (Scopus)

Phosphorylation of the CENP-A amino-terminus in mitotic centromeric chromatin is required for kinetochore function

Goutte-Gattat, D., Shuaib, M., Ouararhni, K., Gautier, T., Skoufias, D. A., Hamiche, A. & Dimitrov, S., 21 May 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 21, p. 8579-8584 6 p.

Research output: Contribution to journalArticle

Kinetochores
Chromatin
14-3-3 Proteins
Phosphorylation
Chromatin Assembly and Disassembly
12 Citations (Scopus)

Physical and functional interaction between heterochromatin protein 1α and the RNA-binding protein heterogeneous nuclear ribonucleoprotein U

Ameyar-Zazoua, M., Souidi, M., Fritsch, L., Robin, P., Thomas, A., Hamiche, A., Percipalle, P., Ait-Si-Ali, S. & Harel-Bellan, A., 9 Oct 2009, In : Journal of Biological Chemistry. 284, 41, p. 27974-27979 6 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoprotein U
RNA-Binding Proteins
Chromatin
Gene Silencing
Purification
56 Citations (Scopus)

SWI/SNF remodeling and p300-dependent transcription of histone variant H2ABbd nucleosomal arrays

Angelov, D., Verdel, A., An, W., Bondarenko, V., Hans, F., Doyen, C. M., Studitsky, V. M., Hamiche, A., Roeder, R. G., Bouvet, P. & Dimitrov, S., 1 Oct 2004, In : EMBO Journal. 23, 19, p. 3815-3824 10 p.

Research output: Contribution to journalArticle

Nucleosomes
Transcription
Histones
Dimers
Enzymes
355 Citations (Scopus)

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

Drané, P., Ouararhni, K., Depaux, A., Shuaib, M. & Hamiche, A., 15 Jun 2010, In : Genes and Development. 24, 12, p. 1253-1265 13 p.

Research output: Contribution to journalArticle

Histone Chaperones
Histones
Chromatin
DNA
Proteins
31 Citations (Scopus)

The docking domain of histone H2A is required for H1 binding and RSC-mediated nucleosome remodeling

Shukla, M. S., Syed, S. H., Goutte-Gattat, D., Richard, J. L. C., Montel, F., Hamiche, A., Travers, A., Faivre-Moskalenko, C., Bednar, J., Hayes, J. J., Angelov, D. & Dimitrov, S., Apr 2011, In : Nucleic Acids Research. 39, 7, p. 2559-2570 12 p.

Research output: Contribution to journalArticle

Nucleosomes
Histones
Chromatin
Cryoelectron Microscopy
Atomic Force Microscopy
22 Citations (Scopus)

The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity

Roulland, Y., Ouararhni, K., Naidenov, M., Ramos, L., Shuaib, M., Syed, S. H., Lone, I. N., Boopathi, R., Fontaine, E., Papai, G., Tachiwana, H., Gautier, T., Skoufias, D., Padmanabhan, K., Bednar, J., Kurumizaka, H., Schultz, P., Angelov, D., Hamiche, A. & Dimitrov, S., 18 Aug 2016, In : Molecular Cell. 63, 4, p. 674-685 12 p.

Research output: Contribution to journalArticle

Nucleosomes
Histones
Centromere
DNA
Cryoelectron Microscopy
121 Citations (Scopus)

The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity

Ouararhni, K., Hadj-Slimane, R., Ait-Si-Ali, S., Robin, P., Mietton, F., Harel-Bellan, A., Dimitrov, S. & Hamiche, A., 1 Dec 2006, In : Genes and Development. 20, 23, p. 3324-3336 13 p.

Research output: Contribution to journalArticle

Histones
Nucleosomes
Shock
Hot Temperature
Genes
31 Citations (Scopus)

The NH2 tail of the novel histone variant H2BFWT exhibits properties distinct from conventional H2B with respect to the assembly of mitotic chromosomes

Boulard, M., Gautier, T., Mbele, G. O., Gerson, V., Hamiche, A., Angelov, D., Bouvet, P. & Dimitrov, S., Feb 2006, In : Molecular and Cellular Biology. 26, 4, p. 1518-1526 9 p.

Research output: Contribution to journalArticle

Nucleosomes
Histones
Chromosomes
Epigenomics
Chromatin
21 Citations (Scopus)

The structural plasticity of SCA7 domains defines their differential nucleosome-binding properties

Bonnet, J., Wang, Y. H., Spedale, G., Atkinson, R. A., Romier, C., Hamiche, A., Pijnappel, W. W. M. P., Timmers, H. T. M., Tora, L., Devys, D. & Kieffer, B., Aug 2010, In : EMBO Reports. 11, 8, p. 612-618 7 p.

Research output: Contribution to journalArticle

Acetyltransferases
Nucleosomes
Plasticity
Zinc Fingers
Zinc
40 Citations (Scopus)
Functional Laterality
Nucleoproteins
Histones
Switches
Nucleosomes
107 Citations (Scopus)

Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma

Herquel, B., Ouararhni, K., Khetchoumian, K., Ignat, M., Teletin, M., Mark, M., Béchade, G., Van Dorsselaer, A., Sanglier-Cianférani, S., Hamiche, A., Cammas, F., Davidson, I. & Losson, R., 17 May 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 20, p. 8212-8217 6 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Hepatocytes
Macromolecular Substances
Retinoic Acid Receptors
Tretinoin
Comment/debate

Cancer cell death and selection: Unexpected putative roles for pRb2/p130, BORIS and CTCF in endoplasmic stress response maintained by the T-antigen

Bronner, C. & Hamiche, A., 1 Jun 2012, In : Cell Cycle. 11, 11, p. 2052-2053 2 p.

Research output: Contribution to journalComment/debate

Viral Tumor Antigens
Cell Death
Neoplasms
Review article
20 Citations (Scopus)

Chaperoning the histone H3 family

Hamiche, A. & Shuaib, M., Mar 2012, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1819, 3-4, p. 230-237 8 p.

Research output: Contribution to journalReview article

Histones
Chromatin
Histone Chaperones
Chromatin Assembly and Disassembly
Dimers
60 Citations (Scopus)

Structure and function insights into the NuRD chromatin remodeling complex

Torchy, M. P., Hamiche, A. & Klaholz, B. P., 8 Jul 2015, In : Cellular and Molecular Life Sciences. 72, 13, p. 2491-2507 17 p.

Research output: Contribution to journalReview article

Chromatin Assembly and Disassembly
Nucleosomes
Histones
Chromatin
Histone Chaperones