• 1441 Citations
  • 16 h-Index
19982019
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Research Output 1998 2019

  • 1441 Citations
  • 16 h-Index
  • 23 Article
  • 1 Review article
1998
20 Citations (Scopus)

Apple messenger RNAs related to bacterial lignostilbene dioxygenase and plant SAUR genes are preferentially expressed in flowers

Watillon, B., Kettmann, R., Arredouani, A., Hecquet, J. F., Boxus, P. & Burny, A., 1 Apr 1998, In : Plant Molecular Biology. 36, 6, p. 909-915 7 p.

Research output: Contribution to journalArticle

Dioxygenases
Plant Genes
Malus
messenger RNA
apples
1999
96 Citations (Scopus)
Insulin-Secreting Cells
Endoplasmic Reticulum
Thapsigargin
Cells
Glucose
2002
45 Citations (Scopus)
Thapsigargin
Islets of Langerhans
Endoplasmic Reticulum
Membrane Potentials
Glucose
71 Citations (Scopus)

SERCA3 ablation does not impair insulin secretion but suggests distinct roles of different sarcoendoplasmic reticulum Ca2+ pumps for Ca2+ homeostasis in pancreatic βcells

Arredouani, A., Guiot, Y., Jonas, J. C., Liu, L. H., Nenquin, M., Pertusa, J. A., Rahier, J., Rolland, J. F., Shull, G. E., Stevens, M., Wuytack, F., Henquin, J. C. & Gilon, P., 1 Nov 2002, In : Diabetes. 51, 11, p. 3245-3253 9 p.

Research output: Contribution to journalArticle

Reticulum
Homeostasis
Insulin
Glucose
Thapsigargin
2004
23 Citations (Scopus)

Atypical Ca2+-induced Ca2+ release from a sarco-endoplasmic reticulum Ca2+-ATPase 3-dependent Ca2+ pool in mouse pancreatic β-cells

Beauvois, M. C., Arredouani, A., Jonas, J. C., Rolland, J. F., Schuit, F., Henquin, J. C. & Gilon, P., 15 Aug 2004, In : Journal of Physiology. 559, 1, p. 141-156 16 p.

Research output: Contribution to journalArticle

Sarcoplasmic Reticulum Calcium-Transporting ATPases
Ryanodine Receptor Calcium Release Channel
Inositol 1,4,5-Trisphosphate Receptors
Glucose
Diazoxide
2008
57 Citations (Scopus)

Cell-permeant NAADP: A novel chemical tool enabling the study of Ca2+ signalling in intact cells

Parkesh, R., Lewis, A. M., Aley, P. K., Arredouani, A., Rossi, S., Tavares, R., Vasudevan, S. R., Rosen, D., Galione, A., Dowden, J. & Churchill, G. C., 1 Jun 2008, In : Cell Calcium. 43, 6, p. 531-538 8 p.

Research output: Contribution to journalArticle

Second Messenger Systems
Inositol 1,4,5-Trisphosphate
Esterification
Health
NAADP
2009
195 Citations (Scopus)

Identification of a chemical probe for NAADP by virtual screening

Naylor, E., Arredouani, A., Vasudevan, S. R., Lewis, A. M., Parkesh, R., Mizote, A., Rosen, D., Thomas, J. M., Izumi, M., Ganesan, A., Galione, A. & Churchill, G. C., 2 Apr 2009, In : Nature Chemical Biology. 5, 4, p. 220-226 7 p.

Research output: Contribution to journalArticle

Small Molecule Libraries
Sea Urchins
Insulin-Secreting Cells
Second Messenger Systems
NAADP
457 Citations (Scopus)

NAADP mobilizes calcium from acidic organelles through two-pore channels

Calcraft, P. J., Ruas, M., Pan, Z., Cheng, X., Arredouani, A., Hao, X., Tang, J., Rietdorf, K., Teboul, L., Chuang, K. T., Lin, P., Xiao, R., Wang, C., Zhu, Y., Lin, Y., Wyatt, C. N., Parrington, J., Ma, J., Evans, A. M., Galione, A. & 1 others, Zhu, M. X., 28 May 2009, In : Nature. 459, 7246, p. 596-600 5 p.

Research output: Contribution to journalArticle

Organelles
Calcium
Cyclic ADP-Ribose
Endoplasmic Reticulum
Sarcoplasmic Reticulum
61 Citations (Scopus)

The acid test: The discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca2+ release channels

Galione, A., Evans, A. M., Ma, J., Parrington, J., Arredouani, A., Cheng, X. & Zhu, M. X., 1 Sep 2009, In : Pflugers Archiv European Journal of Physiology. 458, 5, p. 869-876 8 p.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate Receptors
Ryanodine Receptor Calcium Release Channel
Acids
Calcium Channels
Organelles
2010
21 Citations (Scopus)

An emerging role for NAADP-mediated Ca2+ signaling in the pancreatic β-cell

Arredouani, A., Evans, A. M., Ma, J., Parrington, J., Zhu, M. X. & Galione, A., 1 Sep 2010, In : Islets. 2, 5

Research output: Contribution to journalArticle

Insulin
Incretins
Glucagon-Like Peptide 1
Calcium Signaling
Adenine Nucleotides
62 Citations (Scopus)

NAADP as an intracellular messenger regulating lysosomal calcium-release channels

Galione, A., Morgan, A. J., Arredouani, A., Davis, L. C., Rietdorf, K., Ruas, M. & Parrington, J., 1 Dec 2010, In : Biochemical Society Transactions. 38, 6, p. 1424-1431 8 p.

Research output: Contribution to journalArticle

Calcium Channels
Calcium
Cyclic ADP-Ribose
Lysosomes
Endoplasmic Reticulum
148 Citations (Scopus)

Purified TPC Isoforms Form NAADP Receptors with Distinct Roles for Ca2+ Signaling and Endolysosomal Trafficking

Ruas, M., Rietdorf, K., Arredouani, A., Davis, L. C., Lloyd-Evans, E., Koegel, H., Funnell, T. M., Morgan, A. J., Ward, J. A., Watanabe, K., Cheng, X., Churchill, G. C., Zhu, M. X., Platt, F. M., Wessel, G. M., Parrington, J. & Galione, A., 27 Apr 2010, In : Current Biology. 20, 8, p. 703-709 7 p.

Research output: Contribution to journalArticle

niacin
adenine
Protein Isoforms
phosphates
calcium
20 Citations (Scopus)

Regulation of store-operated Ca2+ entry during the cell cycle

Arredouani, A., Yu, F., Sun, L. & Machaca, K., 1 Jul 2010, In : Journal of Cell Science. 123, 13, p. 2155-2162 8 p.

Research output: Contribution to journalArticle

Cell Division
Cell Cycle
Cell Physiological Phenomena
Interphase
Meiosis
2013
20 Citations (Scopus)

Mechanisms behind the immediate effects of Roux-en-Y gastric bypass surgery on type 2 diabetes

Allen, R. E., Hughes, T. D., Ng, J. L., Ortiz, R. D., Ghantous, M. A., Bouhali, O., Froguel, P. & Arredouani, A., 18 Jul 2013, In : Theoretical Biology and Medical Modelling. 10, 1, 45.

Research output: Contribution to journalArticle

Glucagon-Like Peptide 1
Gastric Bypass
Insulin
Diabetes
Medical problems
2015
1 Citation (Scopus)
Amiloride
Pulmonary Edema
Epithelium
Hydrostatic Pressure
Air
13 Citations (Scopus)
Cell Membrane
Endoplasmic Reticulum
Recycling
Proteins
26 Citations (Scopus)

Nicotinic acid adenine dinucleotide phosphate (NAADP) and endolysosomal two-pore channels modulate membrane excitability and stimulus-secretion coupling in mouse pancreatic β cells

Arredouani, A., Ruas, M., Collins, S. C., Parkesh, R., Clough, F., Pillinger, T., Coltart, G., Rietdorf, K., Royle, A., Johnson, P., Braun, M., Zhang, Q., Sones, W., Shimomura, K., Morgan, A. J., Lewis, A. M., Chuang, K. T., Tunn, R., Gadea, J., Teboul, L. & 8 others, Heister, P. M., Tynan, P. W., Bellomo, E. A., Rutter, G. A., Rorsman, P., Churchill, G. C., Parrington, J. & Galione, A., 28 Aug 2015, In : Journal of Biological Chemistry. 290, 35, p. 21376-21392 17 p.

Research output: Contribution to journalArticle

Ion Channels
Depolarization
Membranes
Glucose
Chemical activation
62 Citations (Scopus)

The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation

Favennec, M., Hennart, B., Caiazzo, R., Leloire, A., Yengo, L., Verbanck, M., Arredouani, A., Marre, M., Pigeyre, M., Bessede, A., Guillemin, G. J., Chinetti, G., Staels, B., Pattou, F., Balkau, B., Allorge, D., Froguel, P. & Poulain-Godefroy, O., 1 Oct 2015, In : Obesity. 23, 10, p. 2066-2074 9 p.

Research output: Contribution to journalArticle

Kynurenine
Mixed Function Oxygenases
Obesity
Kynurenine 3-Monooxygenase
kynureninase
2016
6 Citations (Scopus)

Impact of statistical models on the prediction of type 2 diabetes using non-targeted metabolomics profiling

Yengo, L., Arredouani, A., Marre, M., Roussel, R., Vaxillaire, M., Falchi, M., Haoudi, A., Tichet, J., Balkau, B., Bonnefond, A. & Froguel, P., 1 Oct 2016, In : Molecular Metabolism. 5, 10, p. 918-925 8 p.

Research output: Contribution to journalArticle

Metabolomics
Statistical Models
Type 2 Diabetes Mellitus
ROC Curve
Population
16 Citations (Scopus)

Metabolomic profile of low-copy number carriers at the salivary α-amylase gene suggests a metabolic shift toward lipid-based energy production

Arredouani, A., Stocchero, M., Culeddu, N., Moustafa, J. E. S., Tichet, J., Balkau, B., Brousseau, T., Manca, M. & Falchi, M., 1 Nov 2016, In : Diabetes. 65, 11, p. 3362-3368 7 p.

Research output: Contribution to journalArticle

Metabolomics
Amylases
Fatty Acids
Lipids
Glucose
2017
13 Citations (Scopus)

Relationship between salivary/pancreatic amylase and body mass index: A systems biology approach

Bonnefond, A., Yengo, L., Dechaume, A., Canouil, M., Castelain, M., Roger, E., Allegaert, F., Caiazzo, R., Raverdy, V., Pigeyre, M., Arredouani, A., Borys, J. M., Lévy-Marchal, C., Weill, J., Roussel, R., Balkau, B., Marre, M., Pattou, F., Brousseau, T. & Froguel, P., 23 Feb 2017, In : BMC Medicine. 15, 1, 37.

Research output: Contribution to journalArticle

Systems Biology
Amylases
Body Mass Index
Adiposity
Starch
2018
6 Citations (Scopus)

Inositol 1,4,5-trisphosphate receptors in hypertension

Eid, A. H., El-Yazbi, A. F., Zouein, F., Arredouani, A., Ouhtit, A., Rahman, M. M., Zayed, H., Pintus, G. & Abou-Saleh, H., 26 Jul 2018, In : Frontiers in Physiology. 9, JUL, 1018.

Research output: Contribution to journalReview article

Inositol 1,4,5-Trisphosphate Receptors
Vascular Smooth Muscle
Smooth Muscle Myocytes
Hypertension
Sarcoplasmic Reticulum
2019

DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation

Arredouani, A., Diane, A., Khattab, N., Bensmail, I., Aoude, I., Chikri, M., Mohammad, R., Abou-Samra, A. B. & Dehbi, M., 1 Dec 2019, In : Scientific reports. 9, 1, 4772.

Research output: Contribution to journalArticle

Open Access
Physiological Stress
Glucose
Luciferases
Type 2 Diabetes Mellitus
Insulin Resistance
2 Citations (Scopus)

Evaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation

Siveen, K. S., Prabhu, K. S., Parray, A. S., Merhi, M., Arredouani, A., Chikri, M., Uddin, S., Dermime, S., Mohammad, R. M., Steinhoff, M., Janahi, I. A. & Azizi, F., 1 Dec 2019, In : Scientific Reports. 9, 1, 1554.

Research output: Contribution to journalArticle

Open Access
Transient Receptor Potential Channels
TRPV Cation Channels
Pneumonia
Leukemia
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole