Qatar Biomedical Research Institute

Research Output 2008 2019

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Review article
2019

Acquired resistance to cancer immunotherapy: Role of tumor-mediated immunosuppression

Saleh, R. & Elkord, E., 1 Jan 2019, In : Seminars in Cancer Biology.

Research output: Contribution to journalReview article

Immunotherapy
Immunosuppression
Neoplasms
Tumor Microenvironment
Tumor Escape

Antibodies against alpha-synuclein: tools and therapies

Vaikath, N., Hmila, I., Gupta, V., Erskine, D., Ingelsson, M. & Ali El-Agnaf, O., 1 Jan 2019, In : Journal of Neurochemistry.

Research output: Contribution to journalReview article

Open Access
alpha-Synuclein
Antibodies
Lewy Bodies
Inclusion Bodies
Pathology

CSF and blood biomarkers for Parkinson's disease

Parnetti, L., Gaetani, L., Eusebi, P., Paciotti, S., Hansson, O., Ali El-Agnaf, O., Mollenhauer, B., Blennow, K. & Calabresi, P., 1 Jun 2019, In : The Lancet Neurology. 18, 6, p. 573-586 14 p.

Research output: Contribution to journalReview article

Synucleins
Parkinson Disease
Biomarkers
Intermediate Filaments
Parkinsonian Disorders

Immune checkpoints in the tumor microenvironment

Toor, M., Nair, V., Decock, J. & Elkord, E., 1 Jan 2019, In : Seminars in Cancer Biology.

Research output: Contribution to journalReview article

Tumor Microenvironment
Ligands
Neoplasms
Tumor Escape
Immunosuppressive Agents
2018
2 Citations (Scopus)

AMP-activated protein kinase as a drug target in chronic kidney disease

Allouch, S. & Munusamy, S., 1 Jan 2018, In : Current Drug Targets. 19, 6, p. 709-720 12 p.

Research output: Contribution to journalReview article

AMP-Activated Protein Kinases
Chronic Renal Insufficiency
Pharmaceutical Preparations
Endoplasmic Reticulum Stress
Epithelial-Mesenchymal Transition
10 Citations (Scopus)

Immune checkpoint inhibitors: recent progress and potential biomarkers

Darvin, P., Toor, M., Nair, V. & Elkord, E., 13 Dec 2018, In : Experimental & molecular medicine. 50, 12, 1 p.

Research output: Contribution to journalReview article

Biomarkers
Neoplasms
Oncology
Immunosuppressive Agents
Ports and harbors
31 Citations (Scopus)

Immune checkpoint inhibitors in cancer therapy: A focus on T-regulatory cells: A

Nair, V. & Elkord, E., 1 Jan 2018, In : Immunology and Cell Biology. 96, 1, p. 21-33 13 p.

Research output: Contribution to journalReview article

Regulatory T-Lymphocytes
Neoplasms
Tumor Microenvironment
Therapeutics
Immunotherapy
4 Citations (Scopus)

Inositol 1,4,5-trisphosphate receptors in hypertension

Eid, A. H., El-Yazbi, A. F., Zouein, F., Arredouani, A., Ouhtit, A., Rahman, M. M., Zayed, H., Pintus, G. & Abou-Saleh, H., 26 Jul 2018, In : Frontiers in Physiology. 9, JUL, 1018.

Research output: Contribution to journalReview article

Inositol 1,4,5-Trisphosphate Receptors
Vascular Smooth Muscle
Smooth Muscle Myocytes
Hypertension
Sarcoplasmic Reticulum
17 Citations (Scopus)

NY-ESO-1 based immunotherapy of cancer: Current perspectives

Thomas, R., Al-Khadairi, G., Roelands, J., Hendrickx, W. R., Dermime, S., Bedognetti, D. & Decock, J., 1 May 2018, In : Frontiers in Immunology. 9, MAY, 947.

Research output: Contribution to journalReview article

Immunotherapy
Neoplasms
Testicular Neoplasms
Neoplasm Antigens
Antigens

Prevalence of nephropathy in type 1 diabetes in the Arab world: A systematic review and meta-analysis

Abdel-Motal, U. M., Akila, G., Mohamed, E., Ponnuraja, C., Iken, K., Jahromi, M., Doss, G. P., El Bekay, R. & Zayed, H., 1 Oct 2018, In : Diabetes/Metabolism Research and Reviews. 34, 7, e3026.

Research output: Contribution to journalReview article

Arab World
Type 1 Diabetes Mellitus
Diabetic Nephropathies
Meta-Analysis
Publication Bias
6 Citations (Scopus)

Therapeutic prospects of targeting myeloid-derived suppressor cells and immune checkpoints in cancer

Toor, M. & Elkord, E., 1 Oct 2018, In : Immunology and Cell Biology. 96, 9, p. 888-897 10 p.

Research output: Contribution to journalReview article

Neoplasms
Tumor Escape
Therapeutics
Immunity
Immune Evasion
2017
16 Citations (Scopus)

A user's guide for α-synuclein biomarker studies in biological fluids: Perianalytical considerations

for the Investigating Synuclein Consortium of the Michael J. Fox Foundation for Parkinson's Research, 1 Aug 2017, In : Movement Disorders. 32, 8, p. 1117-1130 14 p.

Research output: Contribution to journalReview article

Synucleins
Parkinson Disease
Biomarkers
Post Translational Protein Processing
Practice Guidelines
401 Citations (Scopus)

Diagnosis and management of dementia with Lewy bodies

McKeith, I. G., Boeve, B. F., DIckson, D. W., Halliday, G., Taylor, J. P., Weintraub, D., Aarsland, D., Galvin, J., Attems, J., Ballard, C. G., Bayston, A., Beach, T. G., Blanc, F., Bohnen, N., Bonanni, L., Bras, J., Brundin, P., Burn, D., Chen-Plotkin, A., Duda, J. E. & 43 others, Ali El-Agnaf, O., Feldman, H., Ferman, T. J., Ffytche, D., Fujishiro, H., Galasko, D., Goldman, J. G., Gomperts, S. N., Graff-Radford, N. R., Honig, L. S., Iranzo, A., Kantarci, K., Kaufer, D., Kukull, W., Lee, V. M. Y., Leverenz, J. B., Lewis, S., Lippa, C., Lunde, A., Masellis, M., Masliah, E., McLean, P., Mollenhauer, B., Montine, T. J., Moreno, E., Mori, E., Murray, M., O'Brien, J. T., Orimo, S., Postuma, R. B., Ramaswamy, S., Ross, O. A., Salmon, D. P., Singleton, A., Taylor, A., Thomas, A., Tiraboschi, P., Toledo, J. B., Trojanowski, J. Q., Tsuang, D., Walker, Z., Yamada, M. & Kosaka, K., 4 Jul 2017, In : Neurology. 89, 1, p. 88-100 13 p.

Research output: Contribution to journalReview article

Lewy Body Disease
REM Sleep Behavior Disorder
Lewy Bodies
Myocardial Perfusion Imaging
Neurobiology
13 Citations (Scopus)

Immunogenomic classification of colorectal cancer and therapeutic implications

Roelands, J., Kuppen, P. J. K., Vermeulen, L., Maccalli, C., Decock, J., Wang, E., Marincola, F. M., Bedognetti, D. & Hendrickx, W. R., 24 Oct 2017, In : International Journal of Molecular Sciences. 18, 10, 2229.

Research output: Contribution to journalReview article

Immune system
immune systems
Colorectal Neoplasms
phenotype
cancer
2016
27 Citations (Scopus)

Glycation in Parkinson's disease and Alzheimer's disease

Vicente Miranda, H., Ali El-Agnaf, O. & Outeiro, T. F., 1 Jun 2016, In : Movement Disorders. 31, 6, p. 782-790 9 p.

Research output: Contribution to journalReview article

Parkinson Disease
Alzheimer Disease
Synucleins
Lewy Bodies
Proteins
112 Citations (Scopus)

Regulatory T cells in the tumor microenvironment and cancer progression: Role and therapeutic targeting

Chaudhary, B. & Elkord, E., 1 Sep 2016, In : Vaccines. 4, 3, 28.

Research output: Contribution to journalReview article

Tumor Microenvironment
Regulatory T-Lymphocytes
Neoplasms
Therapeutics
Immunosuppressive Agents
2015
14 Citations (Scopus)

Targeting α-synuclein as a therapeutic strategy for Parkinsons disease

Lawand, N. B., Saadé, N. E., Ali El-Agnaf, O. & Safieh-Garabedian, B., 3 Oct 2015, In : Expert Opinion on Therapeutic Targets. 19, 10, p. 1351-1360 10 p.

Research output: Contribution to journalReview article

Synucleins
Parkinson Disease
Therapeutics
Antibodies
Prions