Research Output

  • 1308 Citations
  • 22 h-Index
  • 37 Article
  • 2 Review article
  • 1 Chapter
  • 1 Conference contribution
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Article
2019
2 Citations (Scopus)

IKKβ targeting reduces KRAS-induced lung cancer angiogenesis in vitro and in vivo: A potential anti-angiogenic therapeutic target

Carneiro-Lobo, T. C., Scalabrini, L. C., Magalhães, L. D. S., Cardeal, L. B., Rodrigues, F. S., dos Santos, E. O., Baldwin, A. S., Levantini, E., Giordano, R. J. & Bassères, D. S., Apr 2019, In : Lung Cancer. 130, p. 169-178 10 p.

Research output: Contribution to journalArticle

2016

SIRT1 limits adipocyte hyperplasia through c-Myc inhibition

Abdesselem, H., Madani, A., Hani, A., Al-Noubi, M., Goswami, N., Ben Hamidane, H., Billing, A., Pasquier, J., Bonkowski, M. S., Halabi, N., Dalloul, R., Sheriff, M. Z., Mesaeli, N., ElRayess, M., Sinclair, D. A., Graumann, J. & Mazloum, N., 29 Jan 2016, In : Journal of Biological Chemistry. 291, 5, p. 2119-2135 17 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2014

Expression of tissue factor signaling pathway elements correlates with the production of vascular endothelial growth factor and interleukin-8 in human astrocytoma patients

Carneiro-Lobo, T. C., Lima, M. T., Mariano-Oliveira, A., Dutra-Oliveira, A., Oba-Shinjo, S. M., Marie, S. K. N., Sogayar, M. C. & Monteiro, R. Q., 1 Feb 2014, In : Oncology Reports. 31, 2, p. 679-686 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2 Citations (Scopus)
2013

Endothelial Protein C Receptor Function in Murine and Human Breast Cancer Development

Schaffner, F., Yokota, N., Carneiro-Lobo, T., Kitano, M., Schaffer, M., Anderson, G. M., Mueller, B. M., Esmon, C. T. & Ruf, W., 9 Apr 2013, In : PloS one. 8, 4, e61071.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2012

The tick-derived inhibitor Ixolaris prevents tissue factor signaling on tumor cells

Carneiro-Lobo, T. C., Schaffner, F., Disse, J., Ostergaard, H., Francischetti, I. M. B., Monteiro, R. Q. & Ruf, W., 1 Sep 2012, In : Journal of Thrombosis and Haemostasis. 10, 9, p. 1849-1858 10 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2011

Increased expression of protease-activated receptor 1 (PAR-1) in human leukemias

Veiga, C. D. S. B., Carneiro-Lobo, T. C., Coelho, C. J. B. P., Carvalho, S. M. F., Maia, R. C., Vasconcelos, F. C., Abdelhay, E., Mencalha, A. L., Ferreira, A. F., Castro, F. A. & Monteiro, R. Q., 15 Mar 2011, In : Blood Cells, Molecules, and Diseases. 46, 3, p. 230-234 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Involvement of caveolin in probucol-induced reduction in hERG plasma-membrane expression

Guo, J., Li, X., Shallow, H., Xu, J., Yang, T., Massaeli, H., Li, W., Sun, T., Pierce, G. N. & Zhang, S., 1 May 2011, In : Molecular Pharmacology. 79, 5, p. 806-813 8 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

The role of monoubiquitination in endocytic degradation of human ether-a-go-go-related gene (hERG) channels under low K+ conditions

Sun, T., Guo, J., Shallow, H., Yang, T., Xu, J., Li, W., Hanson, C., Wu, J. G., Li, X., Massaeli, H. & Zhang, S., 25 Feb 2011, In : Journal of Biological Chemistry. 286, 8, p. 6751-6759 9 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2010

Extracellular K+ is a prerequisite for the function and plasma membrane stability of HERG channels

Massaeli, H., Guo, J., Xu, J. & Zhang, S., 1 Apr 2010, In : Circulation Research. 106, 6, p. 1072-1082 11 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Involvement of caveolin in low K+-induced endocytic degradation of cell-surface human ether-a-go-go-related gene (hERG) channels

Massaeli, H., Sun, T., Li, X., Shallow, H., Wu, J., Xu, J., Li, W., Hanson, C., Guo, J. & Zhang, S., 27 Aug 2010, In : Journal of Biological Chemistry. 285, 35, p. 27259-27264 6 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2009

Extracellular K+ concentration controls cell surface density of IKr in rabbit hearts and of the HERG channel in human cell lines

Guo, J., Massaeli, H., Xu, J., Jia, Z., Wigle, J. T., Mesaeli, N. & Zhang, S., 1 Sep 2009, In : Journal of Clinical Investigation. 119, 9, p. 2745-2757 13 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Ixolaris, a tissue factor inhibitor, blocks primary tumor growth and angiogenesis in a glioblastoma model

Carneiro-Lobo, T. C., Konig, S., Machado, D. E., Nasciutti, L. E., Forni, M. F., Francischetti, I. M. B., Sogayar, M. C. & Monteiro, R. Q., Nov 2009, In : Journal of Thrombosis and Haemostasis. 7, 11, p. 1855-1864 10 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)
2007

Differential expression and activity of matrix metalloproteinase-2 and -9 in the calreticulin deficient cells

Wu, M., Massaeli, H., Durston, M. & Mesaeli, N., Jul 2007, In : Matrix Biology. 26, 6, p. 463-472 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes

Guo, J., Massaeli, H., Li, W., Xu, J., Luo, T., Shaw, J., Kirshenbaum, L. A. & Zhang, S., 1 Jun 2007, In : Journal of Pharmacology and Experimental Therapeutics. 321, 3, p. 911-920 10 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)
2005

Gene transfer of prostaglandin synthase maintains patency of the newborn lamb arterial duct

Humpl, T., Zaidi, S. H. E., Coe, J. Y., Russell, J., Kaneda, Y., Massaeli, H., Benson, L. N. & Rabinovitch, M., 1 Nov 2005, In : Pediatric Research. 58, 5, p. 976-980 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2004

Apolipoprotein D and platelet-derived growth factor-BB synergism mediates vascular smooth muscle cell migration

Leung, W. C. Y., Lawrie, A., Demaries, S., Massaeli, H., Burry, A., Yablonsky, S., Sarjeant, J. M., Fera, E., Rassart, E., Pickering, J. G. & Rabinovitch, M., 23 Jul 2004, In : Circulation Research. 95, 2, p. 179-186 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2003

Apolipoprotein D Inhibits Platelet-Derived Growth Factor-BB-Induced Vascular Smooth Muscle Cell Proliferated by Preventing Translocation of Phosphorylated Extracellular Signal Regulated Kinase 1/2 to the Nucleus

Sarjeant, J. M., Lawrie, A., Kinnear, C., Yablonsky, S., Leung, W., Massaeli, H., Prichett, W., Veinot, J. P., Rassart, E. & Rabinovitch, M., 1 Dec 2003, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 23, 12, p. 2172-2177 6 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Low matrix metalloproteinase levels precede vascular lesion formation in the JCR:LA-cp rat

Wilson, D., Massaeli, H., Russell, J. C., Pierce, G. N. & Zahradka, P., 1 Jul 2003, In : Molecular and Cellular Biochemistry. 249, 1-2, p. 151-155 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Native and minimally oxidized low density lipoprotein depress smooth muscle matrix metalloproteinase levels

Wilson, D., Massaeli, H., Pierce, G. N. & Zahradka, P., 1 Jul 2003, In : Molecular and Cellular Biochemistry. 249, 1-2, p. 141-149 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

OxLDL stimulates cell proliferation through a general induction of cell cycle proteins

Zettler, M. E., Prociuk, M. A., Austria, J. A., Massaeli, H., Zhong, G. & Pierce, G. N., 1 Feb 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 284, 2 53-2, p. H644-H653

Research output: Contribution to journalArticle

55 Citations (Scopus)
2002

Thromboxane A2 receptors mediate pulmonary hypertension in 60% oxygen-exposed newborn rats by a cyclooxygenase-independent mechanism

Jankov, R. P., Belcastro, R., Ovcina, E., Lee, J., Massaeli, H., Lye, S. J. & Keith Tanswell, A., 15 Jul 2002, In : American Journal of Respiratory and Critical Care Medicine. 166, 2, p. 208-214 7 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
2001

A novel vascular smooth muscle chymase is upregulated in hypertensive rats

Guo, C., Ju, H., Leung, D., Massaeli, H., Shi, M. & Rabinovitch, M., 1 Jan 2001, In : Journal of Clinical Investigation. 107, 6, p. 703-715 13 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Increase in nuclear calcium in smooth muscle cells exposed to oxidized low density lipoprotein

Massaeli, H., Hurtado, C., Austria, A. & Pierce, G. N., 1 Jan 2001, In : Free Radical Research. 34, 1, p. 9-16 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2000

Lesions in ryanodine channels in smooth muscle cells exposed to oxidized low density lipoprotein

Massaeli, H., Austria, J. A. & Pierce, G. N., Feb 2000, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 20, 2, p. 328-334 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Overexpression of SERCA2 ATPase in vascular smooth muscle cells treated with oxidized low density lipoprotein

Massaeli, H., Austria, J. A. & Pierce, G. N., 4 Jul 2000, In : Molecular and Cellular Biochemistry. 207, 1-2, p. 137-141 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
1999

Chronic exposure of smooth muscle cells to minimally oxidized LDL results in depressed inositol 1,4,5-trisphosphate receptor density and Ca2+ transients

Massaeli, H., Austria, J. A. & Pierce, G. N., 17 Sep 1999, In : Circulation Research. 85, 6, p. 515-523 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Oxidized low-density lipoprotein induces cytoskeletal disorganization in smooth muscle cells

Massaeli, H., Hurtado, C., Austria, J. A. & Pierce, G. N., 1 Nov 1999, In : American Journal of Physiology - Heart and Circulatory Physiology. 277, 5 46-5, p. H2017-H2025

Research output: Contribution to journalArticle

18 Citations (Scopus)

The importance of lipid solubility in antioxidants and free radical generating systems for determining lipoprotein peroxidation

Massaeli, H., Sobrattee, S. & Pierce, G. N., 1 Jun 1999, In : Free Radical Biology and Medicine. 26, 11-12, p. 1524-1530 7 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
1998

Susceptibility of LDL to Oxidative Stress in Obstructive Sleep Apnea

Wali, S. O., Bahammam, A. S., Massaeli, H., Pierce, G. N., Iliskovic, N., Singal, P. K. & Kryger, M. H., 1 May 1998, In : Sleep. 21, 3, p. 290-296 7 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)
1997

Oxidation of nuclear membrane cholesterol inhibits nucleoside triphosphatase activity

Ramjiawan, B., Czubryt, M. P., Massaeli, H., Gilchrist, J. S. C. & Pierce, G. N., 22 Jul 1997, In : Free Radical Biology and Medicine. 23, 4, p. 556-562 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
1996

The presence and partitioning of calcium binding proteins in hepatic and cardiac nuclei

Czubryt, M. P., Ramjiawan, B., Gilchrist, J. S. C., Massaeli, H. & Pierce, G. N., Mar 1996, In : Journal of Molecular and Cellular Cardiology. 28, 3, p. 455-465 11 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
1995

Adult cardiomyocytes express functional high-affinity receptors for basic fibroblast growth factor

Liu, L., Pasumarthi, K. B. S., Padua, R. R., Massaeli, H., Fandrich, R. R., Pierce, G. N., Cattini, P. A. & Kardami, E., 1 Jan 1995, In : American Journal of Physiology - Heart and Circulatory Physiology. 268, 5 37-5, p. H1927-H1938

Research output: Contribution to journalArticle

51 Citations (Scopus)
1994

Involvement of lipoproteins, free radicals, and calcium in cardiovascular disease processes

Massaeli, H. & Pierce, G. N., 1 Sep 1994, In : Cardiovascular Research. 28, 9, p. 597-603 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
1993

Modulation of cardiac performance by amiloride and several selected derivatives of amiloride

Pierce, G. N., Cole, W. C., Liu, K., Massaeli, H., Maddaford, T. G., Yi Jing Chen, J. C., McPherson, C. D., Jain, S. & Sontag, D., 1 Jan 1993, In : Journal of Pharmacology and Experimental Therapeutics. 265, 3, p. 1280-1291 12 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

The action of oxidized low density lipoprotein on calcium transients in isolated rabbit cardiomyocytes

Liu, K., Massaeli, H. & Pierce, G. N., 9 Mar 1993, In : Journal of Biological Chemistry. 268, 6, p. 4145-4151 7 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)