Research Output 2009 2019

  • 389 Citations
  • 10 h-Index
  • 26 Article
  • 1 Chapter
  • 1 Review article
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Article
2019

High-resolution protein–protein interaction mapping using all-versus-all sequencing (AVA-Seq)

Andrews, S. S., Ramadan, S., Al-Thani, N. M., Ahmed, I., Ali Mohamoud, Y. & Malek, J., 1 Jan 2019, In : Journal of Biological Chemistry. 294, 30, p. 11549-11558 10 p.

Research output: Contribution to journalArticle

Open Access
Hybrid systems
Proteins
Protein Interaction Mapping
Bacterial Transformation
Fusion reactions

miRNA-dependent regulation of STIM1 expression in breast cancer

Kulkarni, R. P., Elmi, A., Alcantara-Adap, E., Hubrack, S. Z., Nader, N., Yu, F., Dib, M., Ramachandran, V., Najafi Shoushtari, H. & Machaca, K., 10 Sep 2019, In : Scientific reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
MicroRNAs
Breast Neoplasms
Cell Line
Ion Channels
Heterografts
1 Citation (Scopus)

Remodeling of ER-plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca2+ influx in mitosis

Yu, F., Hubrack, S. Z., Chakraborty, S., Sun, L., Alcantara-Adap, E., Kulkarni, R., Billing, A., Graumann, J., Taylor, C. W. & Machaca, K., 1 Jan 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 21, p. 10392-10401 10 p.

Research output: Contribution to journalArticle

Open Access
Mitosis
Endoplasmic Reticulum
Phosphorylation
Cell Membrane
Stromal Interaction Molecule 1

Synthesis of TPEN variants to improve cancer cells selective killing capacity

Ramadan, S., Barlog, M., Roach, J., Al-Hashimi, M., Bazzi, H. S. & Machaca, K., 1 Jun 2019, In : Bioorganic Chemistry. 87, p. 366-372 7 p.

Research output: Contribution to journalArticle

Copper
Chelating Agents
Cells
Toxicity
Metals
2018
1 Citation (Scopus)
Calcium
HeLa Cells
Inositol 1,4,5-Trisphosphate Receptors
Acinar Cells
Mitochondria
2 Citations (Scopus)

The CCT chaperonin is a novel regulator of Ca2+ signaling through modulation of Orai1 trafficking

Hodeify, R., Nandakumar, M., Own, M., Courjaret, R. J., Graumann, J., Hubrack, S. Z. & Machaca, K., 26 Sep 2018, In : Science advances. 4, 9, aau1935.

Research output: Contribution to journalArticle

Chaperonin Containing TCP-1
Recycling
Cell Membrane
Chaperonins
NFATC Transcription Factors
1 Citation (Scopus)

The VLDL receptor regulates membrane progesterone receptor trafficking and non-genomic signaling

Nader, N., Dib, M., Courjaret, R. J., Hodeify, R., Machaca, R., Graumann, J. & Machaca, K., 15 May 2018, In : Journal of Cell Science. 131, 10, jcs212522.

Research output: Contribution to journalArticle

Progesterone Receptors
Progesterone
Membranes
Cytoplasmic and Nuclear Receptors
Endoplasmic Reticulum
1 Citation (Scopus)
Signal transduction
Meiosis
Oocytes
Transition metals
Signal Transduction
2017
4 Citations (Scopus)

AKT1 has dual actions on the glucocorticoid receptor by cooperating with 14-3-3

Habib, T., Sadoun, A., Nader, N., Suzuki, S., Liu, W., Jithesh, P. V. & Kino, T., 5 Jan 2017, In : Molecular and Cellular Endocrinology. 439, p. 431-443 13 p.

Research output: Contribution to journalArticle

Glucocorticoid Receptors
Glucocorticoids
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Proto-Oncogene Proteins c-akt
Phosphorylation
2 Citations (Scopus)

Effects of Hyperglycemia on Vascular Smooth Muscle Ca2+ Signaling

El-Najjar, N., Kulkarni, R. P., Nader, N., Hodeify, R. & Machaca, K., 21 Jun 2017, In : BioMed Research International. 2017, 3691349.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Hyperglycemia
Muscle
Pathology
Medical problems
2016
2 Citations (Scopus)

A novel approach to the expression and purification of recombinant Xenopus Cdc25C

Ramadan, S., Bendriss, G., Hubrack, S. Z., Al-Abdulmalek, A. & Machaca, K., 1 Apr 2016, In : Protein Expression and Purification. 120, p. 148-152 5 p.

Research output: Contribution to journalArticle

Xenopus
Trp-Ser- His-Pro-Gln-Phe-Glu-Lys
Meiosis
Oocytes
Dual-Specificity Phosphatases
9 Citations (Scopus)

Release from Xenopus oocyte prophase I meiotic arrest is independent of a decrease in cAMP levels or PKA activity

Nader, N., Courjaret, R. J., Dib, M., Kulkarni, R. P. & Machaca, K., 1 Jun 2016, In : Development (Cambridge). 143, 11, p. 1926-1936 11 p.

Research output: Contribution to journalArticle

Meiotic Prophase I
Xenopus
Cyclic AMP-Dependent Protein Kinases
Cyclic AMP
Oocytes
8 Citations (Scopus)
Microvilli
Oocytes
Membranes
Epithelium
Oogenesis
2 Citations (Scopus)
Open Access
Xenopus
Oocytes
Cell Membrane
Physiological Phenomena
Muscle Development
2015
13 Citations (Scopus)
Cell Membrane
Endoplasmic Reticulum
Recycling
Proteins
2014
5 Citations (Scopus)

Role for endocytosis of a constitutively active GPCR (GPR185) in releasing vertebrate oocyte meiotic arrest

Nader, N., Dib, M., Daalis, A., Kulkarni, R. P. & Machaca, K., 15 Nov 2014, In : Developmental Biology. 395, 2, p. 355-366 12 p.

Research output: Contribution to journalArticle

Endocytosis
Oocytes
Vertebrates
Meiosis
Progesterone
2013
19 Citations (Scopus)

How to make a good egg!. The need for remodeling of oocyte Ca2+ signaling to mediate the egg-to-embryo transition

Nader, N., Kulkarni, R. P., Dib, M. & Machaca, K., 2013, In : Cell Calcium. 53, 1, p. 41-54 14 p.

Research output: Contribution to journalArticle

Oocytes
Ovum
Embryonic Structures
Fertilization
Imagination
27 Citations (Scopus)

Inositol 1,4,5-trisphosphate (IP3) receptor up-regulation in hypertension is associated with sensitization of Ca2+ release and vascular smooth muscle contractility

Abou-Saleh, H., Pathan, A. R., Daalis, A., Hubrack, S. Z., Abou-Jassoum, H., Al-Naeimi, H., Rusch, N. J. & Machaca, K., 15 Nov 2013, In : Journal of Biological Chemistry. 288, 46, p. 32941-32951 11 p.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate Receptors
Inositol 1,4,5-Trisphosphate
Vascular Smooth Muscle
Muscle
Up-Regulation
35 Citations (Scopus)

Intramolecular shielding maintains the ER Ca2+ sensor stim1 in an inactive conformation

Yu, F., Sun, L., Hubrack, S. Z., Selvaraj, S. & Machaca, K., 1 Jun 2013, In : Journal of Cell Science. 126, 11, p. 2401-2410 10 p.

Research output: Contribution to journalArticle

Calcium
Physiological Phenomena
Cell Degranulation
Membranes
Stromal Interaction Molecule 1
11 Citations (Scopus)
Xenopus
Oocytes
Cations
Genes
Chemical activation
2012
5 Citations (Scopus)

Phosphorylation of the rat Ins(1,4,5)P3 receptor at T930 within the coupling domain decreases its affinity to Ins(1,4,5)P3

Haun, S., Sun, L., Hubrack, S. Z., Yule, D. & Machaca, K., 2012, In : Channels. 6, 5, p. 379-384 6 p.

Research output: Contribution to journalArticle

Phosphorylation
Rats
Meiosis
Allosteric Regulation
Physiology
2011
21 Citations (Scopus)

Endoplasmic reticulum remodeling tunes IP3-dependent Ca2+ release sensitivity

Sun, L., Yu, F., Ullah, A., Hubrack, S. Z., Daalis, A., Jung, P. & Machaca, K., 30 Nov 2011, In : PLoS One. 6, 11, e27928.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate Receptors
Endoplasmic Reticulum
endoplasmic reticulum
calcium
receptors
22 Citations (Scopus)

Role of the STIM1 C-terminal domain in STIM1 clustering

Yu, F., Sun, L., Courjaret, R. J. & Machaca, K., 11 Mar 2011, In : Journal of Biological Chemistry. 286, 10, p. 8375-8384 10 p.

Research output: Contribution to journalArticle

Meiosis
Cluster Analysis
Chemical activation
Xenopus
Endoplasmic Reticulum
2010
80 Citations (Scopus)

Constitutive recycling of the store-operated Ca2+ channel Orai1 and its internalization during meiosis

Yu, F., Sun, L. & Machaca, K., 1 Nov 2010, In : Journal of Cell Biology. 191, 3, p. 523-535 13 p.

Research output: Contribution to journalArticle

Caveolins
Meiosis
Recycling
Fertilization
Oocytes
20 Citations (Scopus)

Regulation of store-operated Ca2+ entry during the cell cycle

Arredouani, A., Yu, F., Sun, L. & Machaca, K., 1 Jul 2010, In : Journal of Cell Science. 123, 13, p. 2155-2162 8 p.

Research output: Contribution to journalArticle

Cell Division
Cell Cycle
Cell Physiological Phenomena
Interphase
Meiosis
2009
92 Citations (Scopus)
Meiosis
Cluster Analysis
Cell Membrane
Alanine
Cell Division